American Thoracic Society Journal news tips for March 2005 (second issue)

ed as body mass index (BMI) at the 95th percentile or higher for age and sex, was significantly associated with asthma and wheezing in a large group of 8- to 11-year-old children. The investigators studied the relationship between obesity, wheeze, and asthma in a community-based cohort of 788 children. Also, the biomedical scientists indicated their data pointed up that unrecognized sleep disordered breathing might explain a portion of the association between obesity and childhood wheezing. Of the 788 youthful participants, 188 either wheezed and/or had asthma. The majority, 600, had no active wheeze or asthma. A significant majority of the children with wheeze were: male, African American, born prematurely, had a primary caregiver with a high school education or less, had a maternal history of asthma, were atopic, and had greater airflow restriction during their lung function test. Also, according to the authors, compared with those who had neither wheeze nor asthma, children with active wheeze had a significantly higher BMI and a much greater prevalence of obesity. The researchers said that although it was unclear how obesity might mediate its effects on both the upper and lower airways, they felt it possible that children with upper and lower airway disease could be less physically active, and, therefore, predisposed to obesity. The research is published in the second issue for March 2005 of the American Thoracic Society's peer-reviewed American Journal of Respiratory and Critical Care Medicine.


As compared with conventional lung function procedures, researchers have developed a new test to measure lung hyperinflation that offers a better single independent gauge for mortality risk in patients with chronic obstructive pulmonary disease (COPD). Investigators in Spain and the United States measured inspiratory capacity-to-total lung capacity in 689 COPD patients from 2 U.S. cl

Contact: Cathy Carlomagno
American Thoracic Society

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