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American Thoracic Society journal news tips for October 2003 (first issue)

TINY AIR POLLUTION PARTICLES TRIGGER CHRONIC BRONCHITIS IN CHILDREN WITH ASTHMA
In a study of the effect of exposure to air pollution on children with asthma in 12 Southern California communities, researchers concluded that organic carbon and nitrogen dioxide deserve greater attention as potential causes of chronic bronchitis in children with asthma. They also assert that previous cross-sectional studies may have underestimated the risks associated with air pollution. The researchers examined 475 children with asthma. Under investigation were different size fractions of particulate matter, particulate organic compound, elemental carbon, nitrogen dioxide, and other-traffic related pollutants. Among the 475 children with asthma in the Children's Health Study, 184 (38.7 percent) had symptoms of bronchitis during the first year they were involved in the analysis. Children with a history of wheeze during the first year before study entry or allergies in the past were significantly more likely to report symptoms. The researchers noted that team sports modified the yearly variability of nitrogen dioxide, which affected only children playing team sports. As assessed by the researchers from 1996 through 1999, the children's symptoms were associated with the yearly variability in the amount of particulate matter. The authors said that organic carbon accounts for almost half of the "fine" particulate matter mass in the Los Angeles air basis. They point out that organic carbon is largely due to emissions from gasoline and diesel vehicle exhaust in Southern California. The study appears in the first issue for October 2003 of the American Thoracic Society's peer-reviewed American Journal of Respiratory and Critical Care Medicine.

AIRWAY INFLAMMATION IN CHILDREN WITH ASTHMA SHOWS PATHOLOGIC FEATURES OF ADULT DISEASE
Italian researchers have shown that pathologic features characteristic of adult asthma are already present in ch
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Contact: Cathy Carlomagno
ccarlomagno@thoracic.org
212-315-6442
American Thoracic Society
3-Oct-2003


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