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Annals of Internal Medicine, tip sheet, November 18, 2003

Among patients who adhered to treatment, survival was similar regardless of the CD4 cell counts at initiation of therapy. Patients with CD4 cell counts of 200 and above who did not refill their drug prescriptions regularly and who presumably did not comply with complicated HAART regimens had higher death rates. The authors conclude that delaying HAART until the CD4 cell count falls to 200 does not increase the mortality rate if the patients comply with the drug regimens. Adherence to the medication regimens is the critical determinant of survival, not the CD4 cell count when HAART is begun, they say.


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Contact: Penny Fuller
pfuller@acponline.org
215-351-2656
American College of Physicians
17-Nov-2003


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