Annals of Internal Medicine tip sheet Nov...( consider the increased risk for breast...)

Annals of Internal Medicine tip sheet Nov. 19, 2002

consider the increased risk for breast cancer when deciding about drinking alcohol, taking postmenopausal hormones and, especially, both together. The limitations of the study are that the large, ongoing Nurses' Health Study relies on self-reported information and the study questions did not differentiate among the kind of PMH taken, e.g., estrogen alone or estrogen with progesterone.

4. Review of Randomized, Controlled Trials of Complementary and Alternative Medicine (CAM) for Menopausal Systems Finds Little Hard Data
Seeking to evaluate complementary and alternative products used for menopausal symptoms, researchers identified 29 randomized, controlled trials (Academia and Clinic, p. 805). They found that black cohosh and foods that contain phytoestrogens, such as soy, show some promise at relieving hot flashes, but they say that clinical trials do not support the use of other herbs or CAM therapies. Well-designed but small trials found that vitamin E, red clover, evening primrose oil, and dong quai were ineffective for hot flashes. Common problems with even these existing studies on CAM use for menopause are that they are small; they often test for only short periods of time, while the herbs or therapies are presumably taken for long periods of time; safety data on long-term use of herbs are inadequate; and herbs and other CAM therapies in the United States lack adequate product quality control.

5. Task Force's Recommendations for Postmenopausal Therapy Appear in Annals
The U.S. Preventive Services Task Force recommends against the use of combined estrogen and progestin therapy for preventing cardiovascular disease and other chronic conditions in postmenopausal women (Clinical Guidelines, p. 834). These recommendations were originally posted on the Annals of Internal Medicine web site (http://www.acponline.org/journals/annals/hrt.htm) on Oct
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Contact: Susan Anderson
sanderson@mail.acponline.org
215-351-2653
American College of Physicians
18-Nov-2002

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Annals of Internal Medicine tip sheet Nov...( consider the increased risk for breast...),Health