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Anti-coagulation drugs found to have different effects in diabetics after heart attack

is no definitive empiric data that supports this theory, Alexander said.

"This analysis shows that enoxaparin appears preferable to abciximab in diabetics because of its overall impact on mortality," Alexander said. "It is also easier to administer and less expensive than abciximab."

Both Pieper and Alexander agree that future studies of enoxaparin and its impact on mortality rates in diabetics are needed.

The ASSENT-3 (Assessment of the Safety and Efficacy of a New Thrombolytic Regimen) trial was conducted at 575 centers between May 2000 and April 2001. The study was funded by Boehringer Ingleheim, Germany; Genentech, South San Francisco, Calif.; and Aventis, Bridgewater, N.J. Pieper and Alexander have no financial in the companies.


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Contact: Richard Merritt
merri006@mc.duke.edu
919-684-4148
Duke University Medical Center
20-Nov-2002


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