HOME >> MEDICINE >> NEWS
Anti-depressant bupropion may alleviate negative mood associated with quitting smoking

A NIDA-funded study at the University of Pennsylvania Transdisciplinary Tobacco Use Research Center has found that the anti-depressant bupropion may help people stop smoking by alleviating negative moods, such as depression and despair, often experienced during nicotine withdrawal. This is the first study to find that such psychological changes may contribute to bupropion's effects on smoking cessation outcomes in a clinical setting.

Dr. Caryn Lerman of the Abramson Cancer Center of the University of Pennsylvania led the research team that examined 251 male and female smokers ages 18 and older. Participants were randomly assigned to receive 10 weeks of treatment with bupropion or a placebo, plus behavioral counseling. Bupropion was initiated on the day of the first counseling session, two weeks before the target quit date. Counseling included nicotine fading (slowly decreasing nicotine intake), coping with cues that trigger smoking, stress management, and relapse prevention. During treatment, participants regularly completed questionnaires about their withdrawal symptoms and positive and negative feelings.

At the end of treatment, 48 percent of bupropion participants were abstinent from smoking, versus 29 percent of those receiving the placebo. The bupropion group exhibited a decrease in negative mood, while those receiving placebo showed an increase in negative mood. Although bupropion reduced the severity of the symptoms of withdrawal, negative mood was more strongly related to smoking relapse.

WHAT IT MEANS: Bupropion may be beneficial for smokers who experience negative moods and who smoke, in part, to manage these symptoms.

#
'"/>

Contact: Blair Gately
Bgately@nida.nih.gov
301-443-6245
NIH/National Institute on Drug Abuse
4-Nov-2002


Page: 1

Related medicine news :

1. Anti-depressants used during pregnancy linked to neonatal withdrawal syndrome
2. Study finds bupropion may be effective smoking cessation aid for women
3. Immersion in virtual world alleviates pain from injury
4. Kadian alleviated chronic pain in patients unsuccessfully treated with well-known therapies
5. Climara Pro (TM) helps alleviate menopausal hot flashes and night sweats
6. Mayo Clinic study shows melatonin helps alleviate violent sleep disorder symptoms
7. Yale researchers create topical estrogen that alleviates sexual dysfunction in menopausal women and eliminates side effects of conventional estrogen
8. Antidepressant drug alleviates hot flashes in men undergoing prostate cancer treatment
9. Anger, negative emotions may trigger stroke
10. Re-analysis of large trials shows greatest benefit of chemotherapy in ER-negative tumors
11. Acute decrease in testosterone level has few negative effects on healthy men

Post Your Comments:
(Date:8/31/2015)... , ... August 31, 2015 , ... The Sundance Film ... on Tuesday, September 1. , “Alive Inside” shadows a social worker who advocates for ... , “It’s a documentary about bringing music to residents in health care centers who ...
(Date:8/31/2015)... ... September 01, 2015 , ... Neuropsychiatric ... injury with emphasis on transcranial near-infrared laser phototherapy ”. , As corresponding author ... has been largely untreatable - with mostly palliative treatments only - and now ...
(Date:8/31/2015)... ... August 31, 2015 , ... David L. Chalnick, ... one of the first doctors in the area to perform minimally invasive hip ... been impressive: faster recovery, decreased immediate and long-term pain, and an accelerated return ...
(Date:8/31/2015)... ... ... NJ Top Docs Presents, Dr. Michael Betsy! Dr. Betsy has been reviewed and approved ... Betsy graduated from Don Bosco Prep in 1990 and was Class Salutatorian. He earned ... in his senior year. He was inducted into the National Honor Society as a ...
(Date:8/31/2015)... Viejo, CA (PRWEB) , ... August 31, 2015 , ... With the FCPX LUT Soft ... footage. A LUT is a Lookup Table that contains a mathematical formula for modifying an ... This pack comes with 60 soft CUBE LUT files. , FCPX LUT Soft requires ...
Breaking Medicine News(10 mins):Health News:Public Invited to Dementia Documentary Screening at North Carolina Retirement Community 2Health News:Near-Infrared Laser Phototherapy for Brain Injury published by Dove Medical Press 2Health News:Near-Infrared Laser Phototherapy for Brain Injury published by Dove Medical Press 3Health News:NJ Top Docs Presents, Dr. David L. Chalnick! 2Health News:NJ Top Docs Presents, Dr. David L. Chalnick! 3Health News:NJ Top Docs Presents, Dr. David L. Chalnick! 4Health News:NJ Top Docs Presents, Dr. Michael Betsy! 2Health News:NJ Top Docs Presents, Dr. Michael Betsy! 3Health News:Pixel Film Studios, FCPX Plugin Developer, Releases FCPX LUT Soft 2
(Date:8/31/2015)... Bionomics Limited (ASX:BNO, ADR:BMICY), a biopharmaceutical company ... for the treatment of diseases of the central nervous ... IND submission has passed review by the US Food ... Phase 1 clinical trial in patients with metastatic colon ... to 31 December 2015. Bionomics, CEO & ...
(Date:8/31/2015)... DUBLIN , Aug. 31, 2015 ... the addition of the "Prescription Pain Drugs ... Medical Marijuana - Global Markets, Competitors and Opportunities: ... to their offering. Pain is ... associated with actual or potential tissue damage. At ...
(Date:8/30/2015)... y LONDRES, August 30, 2015 ... visión holística de l cuidado al ... trayecto   Royal Philips  ... debut europeo de IntelliSpace Cardiovascular , un sistema ... sofisticadas herramientas para acceder, analizar y compartir imágenes cardiovasculares ...
Breaking Medicine Technology:Successful BNC101 IND Submission Paves Way for Development of Promising Cancer Stem Cell Drug Candidate 2Successful BNC101 IND Submission Paves Way for Development of Promising Cancer Stem Cell Drug Candidate 3Successful BNC101 IND Submission Paves Way for Development of Promising Cancer Stem Cell Drug Candidate 4Prescription Pain Drugs Including Opioid, Anticonvulsant, Injectable/ Inhaled, Topical/ Transdermal, Medical Marijuana - 2015-2020 Analysis and Forecasts 2Prescription Pain Drugs Including Opioid, Anticonvulsant, Injectable/ Inhaled, Topical/ Transdermal, Medical Marijuana - 2015-2020 Analysis and Forecasts 3Philips presenta IntelliSpace Cardiovascular en el Congreso ESC 2015 2Philips presenta IntelliSpace Cardiovascular en el Congreso ESC 2015 3
Cached News: