HOME >> MEDICINE >> NEWS
Anti-depressant bupropion may alleviate negative mood associated with quitting smoking

A NIDA-funded study at the University of Pennsylvania Transdisciplinary Tobacco Use Research Center has found that the anti-depressant bupropion may help people stop smoking by alleviating negative moods, such as depression and despair, often experienced during nicotine withdrawal. This is the first study to find that such psychological changes may contribute to bupropion's effects on smoking cessation outcomes in a clinical setting.

Dr. Caryn Lerman of the Abramson Cancer Center of the University of Pennsylvania led the research team that examined 251 male and female smokers ages 18 and older. Participants were randomly assigned to receive 10 weeks of treatment with bupropion or a placebo, plus behavioral counseling. Bupropion was initiated on the day of the first counseling session, two weeks before the target quit date. Counseling included nicotine fading (slowly decreasing nicotine intake), coping with cues that trigger smoking, stress management, and relapse prevention. During treatment, participants regularly completed questionnaires about their withdrawal symptoms and positive and negative feelings.

At the end of treatment, 48 percent of bupropion participants were abstinent from smoking, versus 29 percent of those receiving the placebo. The bupropion group exhibited a decrease in negative mood, while those receiving placebo showed an increase in negative mood. Although bupropion reduced the severity of the symptoms of withdrawal, negative mood was more strongly related to smoking relapse.

WHAT IT MEANS: Bupropion may be beneficial for smokers who experience negative moods and who smoke, in part, to manage these symptoms.

#
'"/>

Contact: Blair Gately
Bgately@nida.nih.gov
301-443-6245
NIH/National Institute on Drug Abuse
4-Nov-2002


Page: 1

Related medicine news :

1. Anti-depressants used during pregnancy linked to neonatal withdrawal syndrome
2. Study finds bupropion may be effective smoking cessation aid for women
3. Immersion in virtual world alleviates pain from injury
4. Kadian alleviated chronic pain in patients unsuccessfully treated with well-known therapies
5. Climara Pro (TM) helps alleviate menopausal hot flashes and night sweats
6. Mayo Clinic study shows melatonin helps alleviate violent sleep disorder symptoms
7. Yale researchers create topical estrogen that alleviates sexual dysfunction in menopausal women and eliminates side effects of conventional estrogen
8. Antidepressant drug alleviates hot flashes in men undergoing prostate cancer treatment
9. Anger, negative emotions may trigger stroke
10. Re-analysis of large trials shows greatest benefit of chemotherapy in ER-negative tumors
11. Acute decrease in testosterone level has few negative effects on healthy men

Post Your Comments:
(Date:5/26/2015)... Viejo, CA (PRWEB) May 26, 2015 ... styles for Final Cut Pro X . ... suspenseful to simple and elegantly styled text. , ... in seconds. , ProTrailer Network can easily complement any ... style desired and within seconds can make professional looking ...
(Date:5/26/2015)... PA (PRWEB) May 26, 2015 ... XML Editor with the Vasont® CCMS to make ... Vasont Systems, a top component content management system ... Integrator (VUI) extension supports oXygen XML Editor Version ... The Vasont Universal Integrator extension merges key editorial ...
(Date:5/26/2015)... Many sexy cocktail dresses inspired ... dress collections recently. Now, TheCelebrityDresses.com is offering great ... to 70% off. The company aims to help ... hundreds of dollars on valuable, trendy formal outfits. ... carpet fashion special occasion dresses. Their dresses are ...
(Date:5/26/2015)... May 26, 2015 Pacifica ... during the Memorial Day weekend, celebrating the outstanding ... on Pacifica’s picturesque Ladera Lane campus, located in ... and alumni traveled to Santa Barbara from all ... , The 2015 commencement ceremonies featured ...
(Date:5/26/2015)... The professionals from Marietta Vet Clinic ... helping local rescue pets with a parking lot cookout ... Kimmerling DDS, Suzanna Aguilera DMD and Garrick McGrath DMD ... 100% of proceeds from the extravaganza. , Tents, grills ... to help save unwanted, local animals. Doctors and ...
Breaking Medicine News(10 mins):Health News:Developers at Pixel Film Studios Release ProTrailer Network for Final Cut Pro X 2Health News:Vasont Systems Certifies the Integration between the Vasont® Component Content Management System and oXygen® XML Editor 17.0 2Health News:Cocktail Dresses Inspired by Celebrities on Sale at TheCelebrityDresses.com 2Health News:Pacifica Graduate Institute Hosted its 2015 Commencement Ceremonies over Memorial Day Weekend 2Health News:Pacifica Graduate Institute Hosted its 2015 Commencement Ceremonies over Memorial Day Weekend 3Health News:"Rescue Animal Cookout" Announced at Verde Pointe Professional Park on June 25, 2015 2
(Date:5/26/2015)... 2015  SI-BONE, Inc., a medical device company that ... minimally invasive surgical (MIS) device indicated for fusion for ... that Laura Francis has joined the company ... the executive management team bringing a wealth of experience ... positions.  Prior to joining SI-BONE, Ms. ...
(Date:5/26/2015)... , May 26, 2015 Connected ... for diverse devices and workflows, aiding diagnosis, monitoring ... an infrastructure to be efficient, stakeholders must first ... place. Logo - http://photos.prnewswire.com/prnh/20150526/218313LOGO ... Sullivan, Healthcare and Medical Device Connectivity and Interoperability, ...
(Date:5/25/2015)... SHENZHEN, China, May 26, 2015  China Nepstar Chain ... a leading retail drugstore chain in China based on ... unaudited financial results for the first quarter ended March 31, ... sales increased by 13.6% compared to the first quarter ... RMB759.1 million (US$122.5 million) compared to RMB678.3 million in the ...
Breaking Medicine Technology:SI-BONE, Inc. Appoints Laura Francis Chief Financial Officer and Closes Additional Round of Growth Capital 2SI-BONE, Inc. Appoints Laura Francis Chief Financial Officer and Closes Additional Round of Growth Capital 3SI-BONE, Inc. Appoints Laura Francis Chief Financial Officer and Closes Additional Round of Growth Capital 4Interoperability among Connected Medical Devices Can Potentially Transform Healthcare 2Interoperability among Connected Medical Devices Can Potentially Transform Healthcare 3China Nepstar Chain Drugstore Ltd. Reports First Quarter 2015 Financial Results 2China Nepstar Chain Drugstore Ltd. Reports First Quarter 2015 Financial Results 3China Nepstar Chain Drugstore Ltd. Reports First Quarter 2015 Financial Results 4China Nepstar Chain Drugstore Ltd. Reports First Quarter 2015 Financial Results 5China Nepstar Chain Drugstore Ltd. Reports First Quarter 2015 Financial Results 6China Nepstar Chain Drugstore Ltd. Reports First Quarter 2015 Financial Results 7China Nepstar Chain Drugstore Ltd. Reports First Quarter 2015 Financial Results 8China Nepstar Chain Drugstore Ltd. Reports First Quarter 2015 Financial Results 9China Nepstar Chain Drugstore Ltd. Reports First Quarter 2015 Financial Results 10China Nepstar Chain Drugstore Ltd. Reports First Quarter 2015 Financial Results 11
Cached News: