HOME >> MEDICINE >> NEWS
Antibiotic could offer promise for treatment of cystic fibrosis

The antibiotic azithromycin could offer some benefit to people with cystic fibrosis if they do not respond to conventional treatment, suggest authors of a study in this week's issue of The Lancet.

Cystic fibrosis is a severe genetic disorder-the most commonly recessively inherited disorder in white populations. Treatment is limited, and aimed at counteracting chronic respiratory infection. The antibiotic azithromycin has anti-inflammatory properties potentially beneficial in cystic fibrosis. Mark Rosenthal from the Royal Brompton Hospital, London, UK, and colleagues investigated the effect of azithromycin on cystic fibrosis after encouraging results from previous pilot studies.

41 children with cystic fibrosis, aged 8-18 years took part in the study. They were randomly allocated azithromycin or placebo for six months, and then switched to either treatment or placebo for a further six months after a two-month 'washout' period. Differences in forced expiratory volume in one second's exhalation (FEV1), measurement of immune response, and quality-of-life assessments were compared between azithromycin and placebo.

Children given azithromycin had a modest improvement in FEV1 of around 5%; however there was wide variation, with 13 children improving and 5 deteriorating by 13%. There was no difference in quality-of-life assessment between azithromycin and placebo; the drug was well tolerated with few reported side effects.

Mark Rosenthal Comments: "A 4-6 month trial of azithromycin is safe, comparatively inexpensive, and could greatly benefit the lung function of patients who do not respond adequately to conventional treatment for cystic fibrosis. The mechanism of benefit remains unknown."


'"/>

Contact: Richard Lane
richard.lane@lancet.com
44-207-424-4949
Lancet
26-Sep-2002


Page: 1

Related medicine news :

1. Antibiotics protect nerves in mice by turning on genes
2. Antibiotic rifampicin shows promise for fighting Parkinsons disease in lab tests
3. Antibiotics within 4 hours of arrival at hospital better for pneumonia patients
4. Antibiotic provides promise in treatment of spinal cord injuries
5. Antibiotic resistant bacteria frequently transmitted between intensive care patients
6. Antibiotic use on swine farms increases efficiency, profits
7. Antibiotic slows atherosclerosis in people with Chlamydia pneumonia antibodies
8. Antibiotics not always beneficial for childhood ear infections
9. Antibiotics help heart patients
10. Antibiotic prescription patterns violate guidelines, increase costs
11. Antibiotic prescribing in local communities is linked to localised resistance

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/18/2018)... ... 2018 , ... Fellow Health Partners, Inc. , a New York based ... have agreed to join its Advisory Board. , CEO Michael N. Brown said, “This ... to guide Fellow Health Partners. They will provide strategic as well as tactical, ‘front ...
(Date:10/17/2018)... ... October 17, 2018 , ... The Jacobs & Cushman San Diego Food ... Banks at a meeting of its Board of Directors. , California Association of ... of California. CAFB provides its member food banks with a range of support services, ...
(Date:10/16/2018)... ... October 16, 2018 , ... CCC ( Compressor ... and downstream operators today announces Total Train Comprehensive Release version 14.1 (TTCR 14.1), ... system components focused on improving cybersecurity defense around turbomachinery. The upgrade process ...
(Date:10/16/2018)... ... October 16, 2018 , ... ... of the Academy of Integrative Health and Medicine’s (AIHM) Visionary Award for his ... , Dr. Pizzorno was selected as AIHM’s recipient of the Visionary Award ...
(Date:10/16/2018)... ... October 16, 2018 , ... 13th Annual FDA ... http://www.fdanews.com/fdainspectionssummit , The 13th Annual FDA Inspections Summit starts in one week. ... feels difficult to keep up. The FDA is focused on any number of ...
Breaking Medicine News(10 mins):
(Date:10/17/2018)... (PRWEB) , ... October 17, 2018 , ... ... Centers, has recently published a new technique documenting the use of placental based ... dental implants. According to Dr. Holtzclaw, “At our DIA Dental Implant Center ...
(Date:10/17/2018)... RESTON, Va. (PRWEB) , ... ... ... Inc., an innovative provider of care management technology solutions, today announced that ... Management (PHM) in Health Plan Accreditation. The review process included a rigorous ...
(Date:10/16/2018)... ... October 16, 2018 , ... Ophthalmic Instruments, ... the American Academy of Ophthalmology’s (AAO) annual session. This four day event will ... McCormick Place in Chicago. AAO 2018 is a leading event for the ophthalmology ...
Breaking Medicine Technology:
Cached News: