HOME >> MEDICINE >> NEWS
Antibiotic could offer promise for treatment of cystic fibrosis

The antibiotic azithromycin could offer some benefit to people with cystic fibrosis if they do not respond to conventional treatment, suggest authors of a study in this week's issue of The Lancet.

Cystic fibrosis is a severe genetic disorder-the most commonly recessively inherited disorder in white populations. Treatment is limited, and aimed at counteracting chronic respiratory infection. The antibiotic azithromycin has anti-inflammatory properties potentially beneficial in cystic fibrosis. Mark Rosenthal from the Royal Brompton Hospital, London, UK, and colleagues investigated the effect of azithromycin on cystic fibrosis after encouraging results from previous pilot studies.

41 children with cystic fibrosis, aged 8-18 years took part in the study. They were randomly allocated azithromycin or placebo for six months, and then switched to either treatment or placebo for a further six months after a two-month 'washout' period. Differences in forced expiratory volume in one second's exhalation (FEV1), measurement of immune response, and quality-of-life assessments were compared between azithromycin and placebo.

Children given azithromycin had a modest improvement in FEV1 of around 5%; however there was wide variation, with 13 children improving and 5 deteriorating by 13%. There was no difference in quality-of-life assessment between azithromycin and placebo; the drug was well tolerated with few reported side effects.

Mark Rosenthal Comments: "A 4-6 month trial of azithromycin is safe, comparatively inexpensive, and could greatly benefit the lung function of patients who do not respond adequately to conventional treatment for cystic fibrosis. The mechanism of benefit remains unknown."


'"/>

Contact: Richard Lane
richard.lane@lancet.com
44-207-424-4949
Lancet
26-Sep-2002


Page: 1

Related medicine news :

1. Antibiotics protect nerves in mice by turning on genes
2. Antibiotic rifampicin shows promise for fighting Parkinsons disease in lab tests
3. Antibiotics within 4 hours of arrival at hospital better for pneumonia patients
4. Antibiotic provides promise in treatment of spinal cord injuries
5. Antibiotic resistant bacteria frequently transmitted between intensive care patients
6. Antibiotic use on swine farms increases efficiency, profits
7. Antibiotic slows atherosclerosis in people with Chlamydia pneumonia antibodies
8. Antibiotics not always beneficial for childhood ear infections
9. Antibiotics help heart patients
10. Antibiotic prescription patterns violate guidelines, increase costs
11. Antibiotic prescribing in local communities is linked to localised resistance

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/5/2019)... ... December 05, 2019 , ... Abide, the #1 Christian meditation ... times this year using Bible-based bedtime stories. Listeners have recovered from bad dreams and ... the Center for Disease Control, one third of Americans suffer from poor sleep, which ...
(Date:12/5/2019)... (PRWEB) , ... December 05, 2019 , ... ... with milestones ranging from launching exceptional products that help people embrace, achieve, and ... world. , “We’ve never been more committed to our mission of impacting world ...
(Date:12/4/2019)... CARDIFF BY THE SEA, Calif. (PRWEB) , ... ... ... Prickly Pear fruit, trademarked as Tex-OE, Opuntia Mesocarp Extract®, provides protection from disruptions ... amazing extract, effective at countering the menace of Jet Lag, is available in ...
(Date:12/4/2019)... STATION, Texas (PRWEB) , ... December 04, 2019 , ... ... a time of physical and mental stress, said Texas A&M AgriLife Extension Service specialists. ... during the holidays to lower stress and benefit your overall wellness,” said Joyce Cavanagh, ...
(Date:12/2/2019)... , ... December 02, 2019 , ... More than $400 ... midnight on December 31. While many people spend their tax-free funds throughout the year, ... on New Year’s Eve. In an effort to help account holders use -- not ...
Breaking Medicine News(10 mins):
(Date:12/6/2019)... ... December 06, 2019 , ... Plant Life Company announced ... LLC (a division of Horticultural Holdings LLC) to recommend Plant Life Company’s line ... FFGS is a team of disciplined and energetic plant lovers formally educated in ...
(Date:12/4/2019)... , ... December 04, 2019 , ... The Harm Reduction ... an Orange County drug and alcohol rehab center and non-profit Intensive ... their team conducted street outreach, trained, and distributed Naloxone amongst members of the own ...
(Date:12/2/2019)... ... December 02, 2019 , ... A Better ... Michael, an intensive mental health facility, announced it has named Tim Ryan and ... development and national advocacy efforts. , "We are proud to announce that Jennifer ...
Breaking Medicine Technology:
Cached News: