Antibiotics Reduce Inflammation In Heart Disease But Effect On Heart Attacks Remains Unproven

DALLAS, March 30 -- Antibiotic treatment can reduce the "markers" of inflammation in the circulation of individuals who have coronary heart disease, but it has not yet been shown to prevent heart attacks, according to early results of a study reported today in Circulation: Journal of the American Heart Association.

These findings have led the study's author and principal investigator, Jeffrey L. Anderson, M.D., chief of the division of cardiology at the University of Utah Medical Center in Salt Lake City, and the study's co-principal investigator, J. Brent Muhlestein, M.D., to call for additional research before conclusions are drawn about the relationship between infection and heart disease. Several small earlier investigations indicated a much more dramatic cause-and-effect scenario, but those results may have been "overstated," Anderson says.

"There is a strong reason to believe that inflammation in the blood vessels plays a much larger role in coronary heart disease than was once thought," he adds.

"We now know that such factors as high cholesterol, cigarette smoking, high blood pressure and diabetes can cause inflammation in the blood vessels, which contributes to atherosclerosis, the cause of heart attacks," says Anderson. "If common infectious agents such as Chlamydia pneuomoniae 'rev up' the atherosclerotic inflammatory process, antibiotic therapy could become a major breakthrough treatment against a disease that kills more Americans each year than any other disease.

"We once thought peptic ulcers were unrelated to bacterial infection, but we know today that they can be effectively treated with antibiotics. We need to find out if the same could prove true of heart disease," he continues.

The ongoing two-year trial reported in Circulation includes 302 individuals with established heart disease and evidence of prior infection by a pneumonia-causing organism called Chlamydia pneumoniae. After six months, indi

Contact: Carole Bullock
American Heart Association

Page: 1 2 3 4

Related medicine news :

1. Antibiotics protect nerves in mice by turning on genes
2. Antibiotics within 4 hours of arrival at hospital better for pneumonia patients
3. Antibiotics not always beneficial for childhood ear infections
4. Antibiotics help heart patients
5. Understanding Why Antibiotics May Be Over-prescribed For Patients With Sore Throats
6. Researchers Synthesize Compounds For New Class Of Antibiotics
7. Reduced progression of atherosclerosis tied to statin drugs lowering fats, protein
8. Reduced risk of institutionalisation in patients with dementia
9. Reduced exposure tobacco products lessen carcinogen exposure, but medicinal nicotine better
10. Reduced scarring helps nerves grow through spinal injuries
11. Reduced risk for developing type 2 diabetes recommended for inclusion in Xenicals European label

Post Your Comments:

(Date:10/8/2019)... (PRWEB) , ... October 08, 2019 , ... ... and support services for the Department of Veterans Affairs Community Care Referrals and ... its implementation of the VA’s Health Share Referral Manager (HSRM), an enterprise-wide system ...
(Date:10/8/2019)... ... October 08, 2019 , ... ... administrators and pathologists, 4medica® President Gregg Church will inform conference attendees ... solution reinventing labs orders management-by starting with the right, clean patient data. The ...
(Date:10/8/2019)... ... October 08, 2019 , ... Dr. Marc Lazare, ... attended an advanced Level III training in Cagliari, Italy, this past September to ... place September 16-19, 2019 at the Sardinia Dental Teaching Center and covered several ...
(Date:10/8/2019)... ... October 08, 2019 , ... MV Transportation, Inc., a ... contract to provide paratransit and senior transportation services to the Regional Transportation Commission ... five-year contract, MV will provide safe and reliable ADA-compliant paratransit and senior citizen ...
(Date:10/8/2019)... ... October 08, 2019 , ... BestRx ... newest electronic prescribing standards. The newest “SCRIPT” standard is mandatory for doctors, pharmacies ... pressure for technology companies to get all providers ready for this format by ...
Breaking Medicine News(10 mins):
(Date:10/11/2019)... ... ... Based on data for the first eight months of the year, 2019 ... 2018. Through August 31, 7,786 deceased donors have provided 23,797 organs for transplant according ... pace, the Association of Organ Procurement Organizations (AOPO) projects 2019 could see an additional ...
(Date:10/10/2019)... ... October 10, 2019 , ... Hospice of Westchester (HOW) recently ... at the Westchester Country Club in Rye. The event honored Grassy Sprain Pharmacy, ... its mission. , “In Celebration” featured live entertainment, culinary delights and a fabulous ...
(Date:10/8/2019)... ... October 09, 2019 , ... “When Seconds Count: Reports From an ... realities of the HEMS world through telling the real stories of the EMS flight ... of published author Jay A. Humphrey, an EMS helicopter pilot. He has been a ...
Breaking Medicine Technology:
Cached News: