HOME >> MEDICINE >> NEWS
Antibiotics help heart patients

DALLAS, Aug. 20 In the largest study of its kind published to date, researchers report that hospitalized heart patients who took antibiotics had a significantly lower risk of returning to the hospital with severe chest pain within one year compared with those on a placebo.

The study suggests that antiobiotics might have an anti-inflammatory benefit. The study appears in today's rapid access issue of Circulation: Journal of the American Heart Association.

Researchers were surprised to find that the reduced risk was not related to the presence of two bacteria suspected of playing a role in heart disease Helicobacter pylori and Chlamydia pneumoniae.

"The beneficial effect of the antibiotics was independent of whether a person was infected with H. pylori or C. pneumonia," says author Michael A. Mendall, M.D., a consultant gastroenterologist at the Mayday Hospital in Croydon, England. "This implies these antibiotics are not working against these organisms. The antibiotics may be acting against other organisms to reduce the overall infectious burden of the body or may have their own anti-inflammatory properties."

The study is the first to compare two different classes of antibiotics in treating acute coronary syndromes. Researchers enrolled 325 patients (225 men and 100 women, ages 39 to 80) hospitalized with a heart attack or unstable angina (severe, unexpected chest pain that occurs at rest). Within 48 hours after being admitted, the patients were randomized to receive amoxycillin, azithromycin, or a placebo for one week. Those in the antibiotic groups also received omeprazole and metronidazole, drugs used in combination with the antibiotics to eradicate H. pylori.

At the start of the study, tests revealed that 157 of 310 patients (51 percent) had antibodies to H. pylori and 132 of 325 patients (41 percent) had antibodies to C. pneumoniae. Blood tests for antibodies detect the dormant bacteria. C. pneumoniae causes
'"/>

Contact: Carole Bullock
carole.bullock@heart.org
214-706-1279
American Heart Association
19-Aug-2002


Page: 1 2 3

Related medicine news :

1. Antibiotics protect nerves in mice by turning on genes
2. Antibiotics within 4 hours of arrival at hospital better for pneumonia patients
3. Antibiotics not always beneficial for childhood ear infections
4. Antibiotics Reduce Inflammation In Heart Disease But Effect On Heart Attacks Remains Unproven
5. Understanding Why Antibiotics May Be Over-prescribed For Patients With Sore Throats
6. Researchers Synthesize Compounds For New Class Of Antibiotics
7. New study in Nature demonstrates protection against cell death during heart attack
8. Uric acid and heart disease
9. Researchers search for first sign of congestive heart failure
10. Hopkins begins human trials with donor adult stem cells to repair muscle damaged from heart attack
11. Extreme exertion, emotion can spark repeat heart attacks

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/23/2017)... (PRWEB) , ... April 23, 2017 , ... ... and managed services announced the achievement of Cisco Select certification and SMB specialization. ... the United States. , In earning the Select Certification, Altura fulfilled ...
(Date:4/22/2017)... , ... April 22, 2017 , ... ... that U.S. consumers can save an average of 70% when buying medication online ... to 97%) are available when purchasing from other countries. The report (chart below) ...
(Date:4/21/2017)... ... April 21, 2017 , ... An April 10 article ... ancient teeth, which reveal a great deal about prehistoric ice-age dental practitioners and their ... have been used to remove decayed dental matter, and that teeth were then filled ...
(Date:4/21/2017)... (PRWEB) , ... April 21, 2017 , ... ... professor Christopher Salas-Wright finds that youth violence is declining—and at noteworthy rates. Between ... relative proportion of young people involved in violence in the United States. The ...
(Date:4/21/2017)... ... April 21, 2017 , ... Brady (NYSE:BRC), a global ... B-595 and B-7569 vinyl label materials received certification for the BS5609 ... tested to remain intact and legible, for use on chemical drums shipped by sea. ...
Breaking Medicine News(10 mins):
(Date:4/20/2017)... 2017 Research and Markets has ... and Market Prospects: Addressing Production Complexities Through Risk Management ... ... Biosimilar Pipeline and Market Prospects: Overcoming Production Complexities Through ... assessment of the current trends in the global biosimilars ...
(Date:4/20/2017)... --  ZappRx, Inc ., a digital health company focused on ... it closed $25 million in Series B funding led by ... Seattle that is part of a ... B round included participation from SR One , who ... (formerly Google Ventures). As part of the financing, ...
(Date:4/20/2017)... 20, 2017 NeuroVive Pharmaceutical AB (Nasdaq ... positive preclinical results demonstrating anti-fibrotic effects with ... steatohepatitis (NASH), in an additional well-validated experimental ... has previously shown similar anti-fibrotic effects in ... scientists present novel data demonstrating anti-fibrotic effects ...
Breaking Medicine Technology:
Cached News: