HOME >> MEDICINE >> NEWS
Antidepressant may help people stop smoking when used with nicotine patch

CHICAGO When used with a transdermal nicotine patch, nortriptyline--an antidepressant medication--may aid in smoking cessation, according to an article in the November 8 issue of The Archives of Internal Medicine, one of the JAMA/Archives journals.

According to background information in the article, smoking is an important preventable cause of death. However, current cessation methods are only partially successful. Several different types of antidepressant medications have been effective in helping people quit smoking.

Allan V. Prochazka, M.D., M.Sc., from the University of Colorado Health Sciences Center, Denver, and colleagues tested the efficacy of nortriptyline in helping people quit smoking cigarettes. Study participants, aged 18 to 65 years, were randomly assigned to one of two groups: one group received nortriptyline (n = 79) and one group received placebo (n = 79). Researchers started both groups with 25 milligrams per day of either nortriptyline or placebo 14 days before the set quit date, and then increased dosage to 75 milligrams per day, as tolerated. A transdermal nicotine patch was administered to all study participants on the determined quit day and was worn for eight weeks.

The researchers found that at six months, cessation rates were 23 percent for those taking nortriptyline and 10 percent for those taking placebo. Neither group experienced a reduction in withdrawal symptoms. However, the nortriptyline group had a significantly higher rate of adverse effects than the placebo group, with 38 percent of participants experiencing dry mouth and 20 percent experiencing drowsiness. Nortriptyline was discontinued in 13 percent of participants due to adverse effects.

The authors write, "there are several possible mechanisms of action for nortriptyline's effect in enhancing smoking cessation. Nortriptyline may reduce depressive symptoms and the need for 'negative affect reduction smoking.' Other antidepressant agents are al
'"/>

Contact: Dana Berry
303-315-5571
JAMA and Archives Journals
8-Nov-2004


Page: 1 2

Related medicine news :

1. Antidepressants may increase risk of abnormal bleeding
2. Antidepressants are not safe for children
3. Antidepressants decrease chronic pain by inhibiting TNF production in brain, UB researchers find
4. Antidepressant drugs may protect brain from damage due to depression
5. Antidepressant provides a cool choice for hot flashes
6. Antidepressants impair cognitive function in the elderly
7. Antidepressant drug alleviates hot flashes in men undergoing prostate cancer treatment
8. Antidepressants Can Lead To Mouth Infections
9. UF Psychiatrists Use Antidepressants To Treat Smoking Addiction
10. Rape Victims Find Relief From Posttraumatic Stress Using The Antidepressant Zoloft.
11. Brain imaging study may hold clues to onset of schizophrenia in people at high risk

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/30/2021)... , ... March 29, 2021 , ... ... the 21st Century , A Virtual Workshop Presented by WCG FDAnews and Cerulean ... 4:30 pm EDT, https://wcg.swoogo.com/modern-sop-and-quality-systems , Are one’s SOPs written for the ...
(Date:3/30/2021)... ... March 29, 2021 , ... According to data released ... reproductive age (13-44) in need of publicly funded contraception live in counties impacted by ... Colorado’s 64 counties have lost some of their Title X resources. , The ...
(Date:3/30/2021)... ... March 29, 2021 , ... Health Literacy Innovations (HLI), a ... confusion due to low health literacy today announces a new partnership with the ... work with ACAP’s member Safety Net Health Plans, those that provide comprehensive health ...
(Date:3/30/2021)... ... ... Dr. Colin Campbell is proud to announce the 1 year anniversary in their new state ... internal medicine and is a primary care specialist who has been practicing for 23 years. ... keep South Jersey healthy one patient at a time. , “Over the past year, Dr. ...
(Date:3/30/2021)... ... March 30, 2021 , ... The COVID-19 ... and survivors; their families; and their caregivers. Crossroads4Hope is addressing the needs of ... emotional support system, MyGo2Support, which meets needs of people impacted by cancer, no ...
Breaking Medicine News(10 mins):
(Date:3/30/2021)... ... March 29, 2021 , ... The University of Texas Health Science Center ... San Antonio Multispecialty and Research Hospital, a destination center for research and treatment of ... In a nod to the COVID-19 pandemic, the ceremony was held virtually. , William ...
(Date:3/30/2021)... ... March 29, 2021 , ... Iora Health ... primary care, has partnered with Devoted Health , one of the fastest-growing ... across Maricopa County and provides seniors with the highest-quality care and experience possible, ...
(Date:3/30/2021)... CITY (PRWEB) , ... March 29, 2021 , ... ... has joined the Vaccine Credential Initiative (VCI), a group bringing together leading health ... record of vaccination status, based on open, interoperable standards. By joining the VCI ...
Breaking Medicine Technology:
Cached News: