HOME >> MEDICINE >> NEWS
Antipsychotic drugs linked to insulin resistance in children

Researchers from the Johns Hopkins Children's Center say a group of drugs known as "atypical antipsychotics" that are commonly used to treat children with aggression, bipolar disorder, and schizophrenia may trigger insulin resistance, a condition that increases the risk of developing Type 2 diabetes and heart disease later in life.

Results of the study linking insulin resistance to the use of these antipsychotics are scheduled for presentation October 20th during the annual meeting of the American Academy of Child and Adolescent Psychiatry in Washington, D.C. (October 19-24)

For the study, the Johns Hopkins team evaluated 11 children, some overweight and others obese, who gained significant amounts of weight (a 10 percent weight increase) while taking the new-generation, or atypical, antipsychotic drugs olanzpine, quetiapine, and risperidone. Considerable weight gain is a common side effect of atypical antipsychotic medications, and is also one of the many factors that can contribute to insulin resistance.

All six children on moderate or high doses of one of these drugs, and three of five children on low doses, had evidence of insulin resistance, a condition in which the body cannot properly use the insulin it produces. This evidence included hypertension, high levels of triglycerides, low levels of high density lipoprotein cholesterol ("good" cholesterol) and increased levels of protein in the urine.

"The insulin resistance seen in these children was greater than what would be expected from weight gain alone, suggesting there is a factor distinct from excess weight that directly induces insulin resistance," says the study's lead author, Mark A. Riddle, M.D., director of the division of child and adolescent psychiatry at the Children's Center.

In general, this group of new-generation antipsychotics creates fewer side effects than older drugs used to treat debilitating psychiatric conditions such as schizophrenia, Riddle sa
'"/>

Contact: Jessica Collins
jcolli31@jhmi.edu
410-516-4570
Johns Hopkins Medical Institutions
20-Oct-2004


Page: 1 2

Related medicine news :

1. Antipsychotic drug prescriptions nearly double for kids with ADHD
2. Antipsychotic drug has few side effects in Alzheimers patients
3. UW research shows risk factors for relapse among health care professionals who abuse drugs
4. New studies show mixed results on epilepsy drugs and birth defects
5. Newly discovered pathway might help in design of cancer drugs
6. Study examines consequences of Thailands war on drugs
7. Computational tool predicts how drugs work in cells, advancing efforts to design better medicines
8. Three anti-platelet drugs used in combination are safe
9. HIV patients may be at risk of heart problems when taking protease inhibitor drugs
10. Clot-busting drugs may help detect potentially deadly leg clots
11. Herb used to treat diabetes works like modern-day prescription drugs, study suggests

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/31/2020)... , ... August 31, 2020 , ... Want to get ... Cerebral Palsy Alliance Research Foundation (CPARF) is thrilled to launch its fourth annual STEPtember ... A fully virtual challenge, STEPtember meets everyone wherever they are at this moment — ...
(Date:8/31/2020)... AURORA, Colo. (PRWEB) , ... August 31, 2020 ... ... premier provider of innovative higher-learning opportunities through high-quality, career-relevant, and affordable online education ... Emergency Responder Psychology . , Among the first of its kind in ...
(Date:8/31/2020)... ... 2020 , ... The pandemic and topsy-turvy economic outlook continues to put financial strain on many ... to trim the fat from our monthly expenses and put more into savings, if possible. ... you have a financial safety net in place in case something were to happen to ...
(Date:8/31/2020)... ... August 31, 2020 , ... In an effort to give ... is donating 10 percent of each hotel room booked with a special new rate ... & Northwest Indiana (RMHC-CNI) , effective immediately. Donations will be applied to any ...
(Date:8/31/2020)... Conn. (PRWEB) , ... August 31, 2020 , ... ... device intended to improve outcomes for patients with advanced heart failure, today announced ... (SBIR) grant in the amount of $555,358 from the National Heart, Lung, and ...
Breaking Medicine News(10 mins):
(Date:9/1/2020)... ... September 01, 2020 , ... ... to serve as Secretary to the Board of Trustees and committee chair of ... United Way is a Denver-based nonprofit organization that fights for the education, health, ...
(Date:8/31/2020)... ... August 31, 2020 , ... ... today announced that they have invested $400,000 in PopBase, one of two start-ups ... with the Global Wellness Institute (GWI). , The competition was part of ...
(Date:8/28/2020)... ... August 28, 2020 , ... Cano Health, ... centers in Florida and San Antonio is happy to announce that it has ... , In this capacity he will serve as community advisor, advertising talent, and ...
Breaking Medicine Technology:
Cached News: