HOME >> MEDICINE >> NEWS
'Artery clearing' system does not provide benefit for patients undergoing PCI

Use of a device and system to clear dislodged "debris" during percutaneous interventions to open a blocked artery following a heart attack does not appear to be clinically beneficial, according to a study in the March 2 issue of JAMA.

Dislodgement of atheromatous (an abnormal fatty deposit in an artery) and thrombotic (blood clot) material ("debris") during percutaneous coronary intervention (PCI) following a heart attack is common. This debris may travel to more distal smaller vessels (beyond the site of arterial blockage) and may result in microcirculatory dysfunction. Prevention of this "distal embolization" may improve reperfusion success, reduce the damage caused by a blocked artery, and enhance event-free survival.

A procedure commonly used with PCI involves use of a specialized guidewire and catheter device to collect liberated embolic debris in the artery. Pilot studies and small randomized trials have demonstrated that distal (situated beyond the point in the obstructed artery) protection of the microcirculation during primary PCI retrieves embolic debris in most patients and may result in greater rates of normal blood flow, improved left ventricular function, and enhanced event-free survival compared with controls.

Gregg W. Stone, M.D., of Columbia University Medical Center and Cardiovascular Research Foundation, New York, and colleagues performed a clinical trial to evaluate the usefulness of distal microcirculatory protection during mechanical reperfusion therapy in acute myocardial infarction (AMI). The randomized controlled trial was conducted at 38 academic and community-based institutions in 7 countries, enrolling 501 patients aged 18 years or older with ST-segment elevation myocardial infarction (STEMI) presenting within 6 hours of symptom onset and undergoing primary PCI or rescue intervention after failed thrombolysis.

The patients were randomized between May 20, 2002, and November 21, 2003 to receive PCI with a
'"/>

Contact: Craig LeMoult
212-305-0820
JAMA and Archives Journals
1-Mar-2005


Page: 1 2 3 4

Related medicine news :

1. First mouse model for multiple system atrophy points to new treatment targets for brain diseases
2. Strengths and failings of U.S. health care system are driven by embedded vested interests
3. Physicists find patterns within seemingly random events of physiological systems
4. Chemists identify immune system mechanism for methamphetamine binges
5. Most hospital executives have substantial concerns about mandatory error reporting systems
6. New hand-held information system for emergency responders
7. Tumor-targeted immune cells cure prostate cancer in mice without causing systemic immune suppression
8. New NHS payment system is no panacea
9. Computerized order entry systems can increase risk of medication errors
10. New system for the analysis of facial movement in three dimensions
11. Study: Two brain systems regulate how we call for help

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/30/2021)... , ... March 29, 2021 , ... ... the 21st Century , A Virtual Workshop Presented by WCG FDAnews and Cerulean ... 4:30 pm EDT, https://wcg.swoogo.com/modern-sop-and-quality-systems , Are one’s SOPs written for the ...
(Date:3/30/2021)... ... March 29, 2021 , ... According to data released ... reproductive age (13-44) in need of publicly funded contraception live in counties impacted by ... Colorado’s 64 counties have lost some of their Title X resources. , The ...
(Date:3/30/2021)... ... March 29, 2021 , ... Health Literacy Innovations (HLI), a ... confusion due to low health literacy today announces a new partnership with the ... work with ACAP’s member Safety Net Health Plans, those that provide comprehensive health ...
(Date:3/30/2021)... ... ... Dr. Colin Campbell is proud to announce the 1 year anniversary in their new state ... internal medicine and is a primary care specialist who has been practicing for 23 years. ... keep South Jersey healthy one patient at a time. , “Over the past year, Dr. ...
(Date:3/30/2021)... ... March 30, 2021 , ... The COVID-19 ... and survivors; their families; and their caregivers. Crossroads4Hope is addressing the needs of ... emotional support system, MyGo2Support, which meets needs of people impacted by cancer, no ...
Breaking Medicine News(10 mins):
(Date:3/30/2021)... ... March 29, 2021 , ... The University of Texas Health Science Center ... San Antonio Multispecialty and Research Hospital, a destination center for research and treatment of ... In a nod to the COVID-19 pandemic, the ceremony was held virtually. , William ...
(Date:3/30/2021)... ... March 29, 2021 , ... Iora Health ... primary care, has partnered with Devoted Health , one of the fastest-growing ... across Maricopa County and provides seniors with the highest-quality care and experience possible, ...
(Date:3/30/2021)... CITY (PRWEB) , ... March 29, 2021 , ... ... has joined the Vaccine Credential Initiative (VCI), a group bringing together leading health ... record of vaccination status, based on open, interoperable standards. By joining the VCI ...
Breaking Medicine Technology:
Cached News: