HOME >> MEDICINE >> NEWS
Artificial organs

THE man who grew a human ear on the back of a mouse has made a breakthrough that brings the prospect of an artificial liver much closer. He believes he has solved the problem of growing the complex networks of blood vessels that artificial organs would need to sustain themselves within the body.

Until now, researchers trying to build replacement body parts have been limited to making relatively simple tissue, such as thin sections of cartilage and skin. That's because it has not been possible to grow the deep networks of blood vessels that organs need to stay alive. But now Jay Vacanti at Massachusetts General Hospital in Boston and Jeffrey Borenstein at the nearby Draper Lab have shown that it can be done.

Artificial organs would be a boon because organ donations cannot keep pace with demand. In the US, some 80,000 people are waiting for kidney, liver or heart transplants. And of the 23,000 Americans who need a liver, only 5000 got their wish last year. Artificial organs would slash these waiting lists and solve the big problem of organ rejection by growing them from the patient'scells.

Tissue engineers can already grow simple body tissues such as knee cartilage. They start with a shaped, porous scaffold made from a biodegradable plastic like polylactic glycolic acid (PLGA). The scaffold is "seeded" by plunging it into a solution of the patient's cells and then immersing it in a nutrient solution. As the cells multiply and clump together, the scaffold dissolves, leaving a piece of cartilage ready for transplant.

The new cartilage can survive because oxygen and nutrients from surrounding body fluids diffuse into the cells. But this doesn't work for the thicker tissues typical of livers and kidneys because nutrients can only diffuse across a few cell layers. Instead, they need an internal blood supply to deliver nutrients to cells deep inside the organ. "Without a blood supply, the tissue dies," says Borenstein, a micro-engineering exper
'"/>

Contact: Claire Bowles
claire.bowles@rbi.co.uk
44-207-331-2751
New Scientist
24-Apr-2002


Page: 1 2 3

Related medicine news :

1. Artificial liver trials show progress, as transplant candidates wait
2. Artificial liver moves toward commercialization
3. New Type Of Artificial Surfactant Shows Promise In Treating Lung Disease
4. Trial Begins For First Artificial Liver Device Using Human Cells
5. Infectious agent linked to mad cow disease found in organs other than the brain
6. Blacks and poor more likely to donate than receive many types of transplant organs
7. Study finds HER2-positive breast cancer invades organs due to fatal chemical attraction
8. Targeting cell fusion as possible way to repair organs, deliver cancer vaccines
9. Improved procurement could more than double availability of life-saving transplant organs
10. Imaging study reveals effect of smoking on peripheral organs
11. PET scans show cigarette smoke affects peripheral organs

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Artificial organs

(Date:8/29/2015)... ... August 29, 2015 , ... ... freely market and sell Arterosil and Arterosil HP, and that all claims and ... sued Vascular Health Sciences, LLC (VHS) in the United States District Court for ...
(Date:8/28/2015)... ... August 28, 2015 , ... Joining a ... Memorial Hospital recently transitioned management companies to partner with Wound Care Advantage (WCA) ... outpatient wound center. , Transitioning wound care management providers can be a ...
(Date:8/28/2015)... ... August 28, 2015 , ... Approximately ... the Zoo to celebrate children helping children, a thank you to the many ... Ohio have contributed to the United Methodist initiative to end malaria deaths. , ...
(Date:8/28/2015)... CA (PRWEB) , ... August 28, 2015 , ... An ... journey that local pizza maker Paul LaRocco has gone through to open a pizzeria ... approval and permitting process tends to take several months, but the current process, having ...
(Date:8/28/2015)... ... August 28, 2015 , ... For Dallas, the time is nearing for ... subsidiary USPI Tenet Health. , The American Heart Association hosts their well-known Heart Walk ... believe that together, a difference can be made. Walkers can participate in the cause ...
Breaking Medicine News(10 mins):Health News:Decatur County Memorial Hospital Transitions Wound Center Management To Wound Care Advantage and the Luvo Operating System 2Health News:Decatur County Memorial Hospital Transitions Wound Center Management To Wound Care Advantage and the Luvo Operating System 3Health News:Decatur County Memorial Hospital Transitions Wound Center Management To Wound Care Advantage and the Luvo Operating System 4Health News:Saturday’s United Methodist Event at Columbus Zoo Celebrates Imagine No Malaria 2Health News:Saturday’s United Methodist Event at Columbus Zoo Celebrates Imagine No Malaria 3Health News:Article on Building Approval Process for LA Business Highlights the Need for a Bridge Between Businesses and City Officials, says Fire Protection Group Inc. 2Health News:North Central Surgical Center’s Subsidiary Participates in Walk 2
(Date:8/28/2015)... N.C. , Aug. 28, 2015  Delays ... research projects can slow down the decision-making process, ... is, therefore, absolutely critical for biopharmaceutical companies to ... research approval process for quicker and more meaningful ... by Best Practices, LLC, nearly three-quarters of benchmarked ...
(Date:8/28/2015)... Research and Markets ... the "12th Annual Report and Survey of ... their offering. The 2015 12th Annual ... Production is the most recent study of biotherapeutic ... future capacity and production. The report contains the ...
(Date:8/28/2015)... -- Research and Markets ( http://www.researchandmarkets.com/research/rktnl9/investigation ... "Investigation Report on China,s Insulin Aspart Market, 2010-2019" ... by Novo Nordisk, insulin aspart (under the trade ... the treatment of diabetes. Compared with human insulin, ... starts working fast and reports higher peak of ...
Breaking Medicine Technology:Expediting the Pharmaceutical Market Research Process for Faster Insights 212th Annual Report and Survey of Biopharmaceutical Manufacturing Capacity and Production 2China Insulin Aspart Market Report 2010-2019 - Developed by Novo Nordisk 2
Cached News: