HOME >> MEDICINE >> NEWS
Artificial organs

THE man who grew a human ear on the back of a mouse has made a breakthrough that brings the prospect of an artificial liver much closer. He believes he has solved the problem of growing the complex networks of blood vessels that artificial organs would need to sustain themselves within the body.

Until now, researchers trying to build replacement body parts have been limited to making relatively simple tissue, such as thin sections of cartilage and skin. That's because it has not been possible to grow the deep networks of blood vessels that organs need to stay alive. But now Jay Vacanti at Massachusetts General Hospital in Boston and Jeffrey Borenstein at the nearby Draper Lab have shown that it can be done.

Artificial organs would be a boon because organ donations cannot keep pace with demand. In the US, some 80,000 people are waiting for kidney, liver or heart transplants. And of the 23,000 Americans who need a liver, only 5000 got their wish last year. Artificial organs would slash these waiting lists and solve the big problem of organ rejection by growing them from the patient'scells.

Tissue engineers can already grow simple body tissues such as knee cartilage. They start with a shaped, porous scaffold made from a biodegradable plastic like polylactic glycolic acid (PLGA). The scaffold is "seeded" by plunging it into a solution of the patient's cells and then immersing it in a nutrient solution. As the cells multiply and clump together, the scaffold dissolves, leaving a piece of cartilage ready for transplant.

The new cartilage can survive because oxygen and nutrients from surrounding body fluids diffuse into the cells. But this doesn't work for the thicker tissues typical of livers and kidneys because nutrients can only diffuse across a few cell layers. Instead, they need an internal blood supply to deliver nutrients to cells deep inside the organ. "Without a blood supply, the tissue dies," says Borenstein, a micro-engineering exper
'"/>

Contact: Claire Bowles
claire.bowles@rbi.co.uk
44-207-331-2751
New Scientist
24-Apr-2002


Page: 1 2 3

Related medicine news :

1. Artificial liver trials show progress, as transplant candidates wait
2. Artificial liver moves toward commercialization
3. New Type Of Artificial Surfactant Shows Promise In Treating Lung Disease
4. Trial Begins For First Artificial Liver Device Using Human Cells
5. Infectious agent linked to mad cow disease found in organs other than the brain
6. Blacks and poor more likely to donate than receive many types of transplant organs
7. Study finds HER2-positive breast cancer invades organs due to fatal chemical attraction
8. Targeting cell fusion as possible way to repair organs, deliver cancer vaccines
9. Improved procurement could more than double availability of life-saving transplant organs
10. Imaging study reveals effect of smoking on peripheral organs
11. PET scans show cigarette smoke affects peripheral organs

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/28/2017)... Clara, CA (PRWEB) , ... April 28, 2017 ... ... is pleased to announce the integration of Microsoft(R) Word(TM) Online(TM), which enables sleep ... user experience, since it streamlines the reporting process and provides a familiar interface ...
(Date:4/28/2017)... (PRWEB) , ... April 28, 2017 , ... Getting enough sleep affects much more than ... (NSF), going just 19 hours without sleep can compromise motor reaction time, which can increase ... and Amica Insurance is sharing the following tips from the NSF to help you sleep ...
(Date:4/28/2017)... ... 2017 , ... Ushio America proudly introduces the new ... solution for F32T8 fluorescent lamps on most instant-start and programmed-start electronic ballasts so ... lamps utilize the existing electronic ballast, saving labor and maintenance costs. It’s easy ...
(Date:4/28/2017)... ... April 28, 2017 , ... ... exposed to more adverse experiences than children in the general population. That’s because ... abuse, neglect or other family challenges. While no fault of their own, youth ...
(Date:4/28/2017)... ... April 28, 2017 , ... ... could substantially improve drug safety and minimize the cost of development. In this ... channel inhibition using cell lines and for cardiac toxicity using induced pluripotent stem ...
Breaking Medicine News(10 mins):
(Date:4/20/2017)... Research and Markets has announced the addition of ... Regional Outlook, Growth Trends, Key Players, Competitive Strategies and Forecasts, ... ... at US$ 7,167.6 Mn in 2015, and is expected to ... of 5.6% from 2016 to 2024. The ...
(Date:4/20/2017)... , April 20, 2017 Research and ... Pharmaceutical Contract Manufacturing Services Market Analysis By Service (Manufacturing, Research), ... Forecasts, 2014 - 2025" report to their offering. ... The Latin American pharmaceutical ... billion by 2025 Low drug registration cost in ...
(Date:4/19/2017)... The Mobile X-Ray product segment is the most attractive market ... period Mobile X-Ray segment is the largest segment ... market, which is estimated to be valued at more than ... 7% over the forecast period. Mobile X-Ray segment is expected ... Mn in 2017 over 2016. The segment,s revenue in the ...
Breaking Medicine Technology:
Cached News: