HOME >> MEDICINE >> NEWS
Artificial organs

THE man who grew a human ear on the back of a mouse has made a breakthrough that brings the prospect of an artificial liver much closer. He believes he has solved the problem of growing the complex networks of blood vessels that artificial organs would need to sustain themselves within the body.

Until now, researchers trying to build replacement body parts have been limited to making relatively simple tissue, such as thin sections of cartilage and skin. That's because it has not been possible to grow the deep networks of blood vessels that organs need to stay alive. But now Jay Vacanti at Massachusetts General Hospital in Boston and Jeffrey Borenstein at the nearby Draper Lab have shown that it can be done.

Artificial organs would be a boon because organ donations cannot keep pace with demand. In the US, some 80,000 people are waiting for kidney, liver or heart transplants. And of the 23,000 Americans who need a liver, only 5000 got their wish last year. Artificial organs would slash these waiting lists and solve the big problem of organ rejection by growing them from the patient'scells.

Tissue engineers can already grow simple body tissues such as knee cartilage. They start with a shaped, porous scaffold made from a biodegradable plastic like polylactic glycolic acid (PLGA). The scaffold is "seeded" by plunging it into a solution of the patient's cells and then immersing it in a nutrient solution. As the cells multiply and clump together, the scaffold dissolves, leaving a piece of cartilage ready for transplant.

The new cartilage can survive because oxygen and nutrients from surrounding body fluids diffuse into the cells. But this doesn't work for the thicker tissues typical of livers and kidneys because nutrients can only diffuse across a few cell layers. Instead, they need an internal blood supply to deliver nutrients to cells deep inside the organ. "Without a blood supply, the tissue dies," says Borenstein, a micro-engineering exper
'"/>

Contact: Claire Bowles
claire.bowles@rbi.co.uk
44-207-331-2751
New Scientist
24-Apr-2002


Page: 1 2 3

Related medicine news :

1. Artificial liver trials show progress, as transplant candidates wait
2. Artificial liver moves toward commercialization
3. New Type Of Artificial Surfactant Shows Promise In Treating Lung Disease
4. Trial Begins For First Artificial Liver Device Using Human Cells
5. Infectious agent linked to mad cow disease found in organs other than the brain
6. Blacks and poor more likely to donate than receive many types of transplant organs
7. Study finds HER2-positive breast cancer invades organs due to fatal chemical attraction
8. Targeting cell fusion as possible way to repair organs, deliver cancer vaccines
9. Improved procurement could more than double availability of life-saving transplant organs
10. Imaging study reveals effect of smoking on peripheral organs
11. PET scans show cigarette smoke affects peripheral organs

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/10/2016)... (PRWEB) , ... February 10, 2016 , ... ... and Video Remote Interpreting (VRI) within Healthcare, recently partnered with Heart City ... interpreting (VRI). , For nearly 23 years, Heart City Health Center has provided ...
(Date:2/10/2016)... ... 2016 , ... Emergency rooms provide emergency care to stabilize critical health issues, ... with dental emergencies at risk of losing a tooth or their smiles. Dr. Marine ... Common dental emergencies include:, , Avulsed or knocked-out teeth , ...
(Date:2/10/2016)... ... February 10, 2016 , ... Ongoing news of the ... Care Association™ (ALCA) to conduct a survey that takes a closer look at cases ... illustrates the prevalence and causes of TBI among the aging population, and identifies the ...
(Date:2/10/2016)... Alachua, FL (PRWEB) , ... February 10, 2016 , ... ... repair market, will report results for the fourth quarter and full year ended December ... will host a conference call and webcast for the investment community following the release ...
(Date:2/10/2016)... ... 2016 , ... For additional information contact Phyllis Strupp 480-488-5858 , Brain improves ... The Ultimate Guide to Brain Training" by award-winning author Phyllis Strupp explains ... is March 16, 2016. A free review copy is available to the media ...
Breaking Medicine News(10 mins):
(Date:2/10/2016)... HERTFORDSHIRE, England and PITTSBURGH, Feb. 10, 2016 Mylan ... for the quarter and year ended December 31, 2015. ... , Full year adjusted total revenues of $9.45 ... the prior year; GAAP total revenues of $9.43 billion. ... non-U.S. developed markets specialty and branded generics business (the ...
(Date:2/10/2016)... February 10, 2016 --> ... (Liquid & Gas), and Spectroscopy Market by Industry (Oil & ... Pulp & Paper, Metal & Mining, and Others), And ... the global market is expected to grow to USD ... 8.6% between 2015 and 2020. Browse 82 ...
(Date:2/10/2016)... -- CSI Specialty Group (CSI) expanded its specialty pharmacy ... Pharmacy Podcast. A free, weekly show, the Specialty Pharmacy ... discussion and context amongst specialty pharmacy peers and professionals. ... The Specialty Pharmacy Podcast, hosted by industry leader ... DiMascio, CHE, CMCE, CPC, is available for streaming and/or ...
Breaking Medicine Technology:
Cached News: