HOME >> MEDICINE >> NEWS
Artificial organs

t.

In a bid to beat the problem, Borenstein teamed up with transplant surgeon Vacanti, who in 1997 famously grew a human ear from cartilage cells on the back of a mouse. The idea the pair hatched involves copying the blood vessel network of a real liver and using 3D computer modelling and machining to mimic its construction.

First, they injected a liquid plastic into the blood vessels of a liver. Once the plastic had solidified, they dissolved the liver tissue, leaving a solid cast of the organ's blood vessels. From this model they were able to take measurements of vessel diameters, branching angles and the distances between vessels. They fed the numbers into software that built a 3D fractal-like computer model of a liver's blood supply. When they simulated blood flowing through the "liver", it had the same blood flow properties as the living system, says Borenstein.

The 3D blood vessel model is then "sliced up" inside the computer, dividing the model into a series of horizontal layers, each of which is used to make a silicon mould. PLGA is then poured into each mould to make the many slices that when sandwiched together, under pressure and heat, create a scaffold for the artificial liver. It's shot through with channels as small as the finest capillaries and as large as the organ's main veins and arteries.

The scaffold then has to be seeded with the cells that make up the solid part of the liver. As well as hepatocytes, which perform key liver functions such as breaking down toxins and metabolising proteins and carbohydrates, there are at least six other types of cells. Borenstein says there are two possible ways of seeding this complex network of different cell types. You could seed each layer separately with different cell types, or inject them from the outside. But the pair won't yet say how this is done.

To get the blood supply working, a solution of endothelial cells, the cells that normally line blood vessels, is pumped into t
'"/>

Contact: Claire Bowles
claire.bowles@rbi.co.uk
44-207-331-2751
New Scientist
24-Apr-2002


Page: 1 2 3

Related medicine news :

1. Artificial liver trials show progress, as transplant candidates wait
2. Artificial liver moves toward commercialization
3. New Type Of Artificial Surfactant Shows Promise In Treating Lung Disease
4. Trial Begins For First Artificial Liver Device Using Human Cells
5. Infectious agent linked to mad cow disease found in organs other than the brain
6. Blacks and poor more likely to donate than receive many types of transplant organs
7. Study finds HER2-positive breast cancer invades organs due to fatal chemical attraction
8. Targeting cell fusion as possible way to repair organs, deliver cancer vaccines
9. Improved procurement could more than double availability of life-saving transplant organs
10. Imaging study reveals effect of smoking on peripheral organs
11. PET scans show cigarette smoke affects peripheral organs

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Artificial organs

(Date:4/26/2015)... FL (PRWEB) April 26, 2015 India ... pioneered in delivering valuable community services to the Asian ... developmental projects in India for more than two decades. ... hundreds and thousands of subscribers around the world with ... source at that time. The Immigration Law Forum Digest, ...
(Date:4/26/2015)... (PRWEB) April 26, 2015 In an article ... State University evaluated the head-neck biomechanics occurring during the use ... study were able to determine that use of a tablet ... 3 to 5 times - more than when the neck ... for such a study, but pointing out the potential hazards ...
(Date:4/26/2015)... April 26, 2015 The grand celebration got ... by Deb Dettor, CCAR’s Managing Director. Deb then introduced Sandy ... was not in attendance because of his Walk for ... Phil was able to express his gratitude to the volunteers ... for their dedication to carrying out CCAR’s mission. Volunteer ...
(Date:4/25/2015)... DC (PRWEB) April 26, 2015 The ... Seniors (ACE.S) , a national endeavor to prepare nurses ... adults, is a great success, according to a new ... the program's original funding partners. , The project ... of Philadelphia (CCP), under the direction of Elaine Tagliareni, ...
(Date:4/25/2015)... 26, 2015 Avid Collector Andrew Hawley ... Rolling Stones Greensboro Coliseum concert posters. The concert was ... the Stone's Second American Tour. , According to ... out of Baltimore, Maryland. This poster blank was used ... southern cites. Globe uses garish lettering and colors on ...
Breaking Medicine News(10 mins):Health News:North American Telugu Society Bestows Community Service Award to India Network Foundation for Its Generosity and Sponsor of Visitor Health Insurance to Indian Visitors 2Health News:North American Telugu Society Bestows Community Service Award to India Network Foundation for Its Generosity and Sponsor of Visitor Health Insurance to Indian Visitors 3Health News:Avoiding the Pain in the Neck Caused by Overuse of Technology 2Health News:Avoiding the Pain in the Neck Caused by Overuse of Technology 3Health News:Avoiding the Pain in the Neck Caused by Overuse of Technology 4Health News:The Connecticut Community for Addiction Recovery (CCAR) honors its volunteers during National Volunteer Recognition Week. 2Health News:Hartford Foundation Report Details Success of NLN's Advancing Care Excellence for Seniors (ACE.S) Program 2Health News:Hartford Foundation Report Details Success of NLN's Advancing Care Excellence for Seniors (ACE.S) Program 3
(Date:4/24/2015)... , und BARCELONA , ... Nr. 4410) iCAD, Inc. (Nasdaq: ICAD ... Bildanalyse, Lösungen für Behandlungsabläufe und Strahlentherapie für ... heute die sofortige Verfügbarkeit des ersten Xoft ... (eBx ® ) System ® in ...
(Date:4/24/2015)... -- Bayer Corporation hosted its annual "Take Your Child to Work ... headquarters.  This is Bayer,s second "Take Your Child To Work ... campus, and Thursday,s event welcomed 230 children ready to see ... Fortunately, for the kids, this was not just another ... "Science For A Better Life," Bayer made sure that "Take ...
(Date:4/24/2015)... , April 24, 2015   Vestagen Technical Textiles, ... VESTEX ® , has recently received two notable innovation ... global competition that recognizes innovations with potential to create ... last night in New York City ... Material Science "Protection & Safety" category. The awards honor ...
Breaking Medicine Technology:Erste Klinik in Spanien setzt das Xoft Electronic Brachytherapy System für die Behandlung von Brustkrebs im Frühstadium, nicht-melanozytärem Hautkrebs und gynäkologischen Krebserkrankungen ein 2Erste Klinik in Spanien setzt das Xoft Electronic Brachytherapy System für die Behandlung von Brustkrebs im Frühstadium, nicht-melanozytärem Hautkrebs und gynäkologischen Krebserkrankungen ein 3Erste Klinik in Spanien setzt das Xoft Electronic Brachytherapy System für die Behandlung von Brustkrebs im Frühstadium, nicht-melanozytärem Hautkrebs und gynäkologischen Krebserkrankungen ein 4Erste Klinik in Spanien setzt das Xoft Electronic Brachytherapy System für die Behandlung von Brustkrebs im Frühstadium, nicht-melanozytärem Hautkrebs und gynäkologischen Krebserkrankungen ein 5Erste Klinik in Spanien setzt das Xoft Electronic Brachytherapy System für die Behandlung von Brustkrebs im Frühstadium, nicht-melanozytärem Hautkrebs und gynäkologischen Krebserkrankungen ein 6Bayer Hosts "Take Your Child to Work Day" 2Bayer Hosts "Take Your Child to Work Day" 3Bayer Hosts "Take Your Child to Work Day" 4VESTEX Wins Innovation Honors from Edison Awards & Apparel Magazine 2VESTEX Wins Innovation Honors from Edison Awards & Apparel Magazine 3
Cached News: