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Asymptomatic cardiovascular changes are powerful predictor of future heart disease

dence of subclinical disease early on faced a substantially higher risk of cardiac events later on, the study found.

Black women with subclinical disease had more than a two-and-a-half-fold higher risk of a subsequent cardiac event than those who did not have early evidence of cardiovascular changes the highest risk noted. Black and white men were found to be nearly two times as likely to have clinical disease after 10 years if evidence of disease was present earlier. White women with subclinical disease had a 60 percent higher risk of a subsequent cardiac event, the study found.

"In contrast to traditional measures that prove a snapshot picture of risk factor levels at one point in time, the index of measures reflects cumulative vascular burden that can more accurately point to later risk for coronary artery disease," Dr. Kuller continued. "Earlier interventions, perhaps with drugs to treat cholesterol and hypertension, as well as controlling diabetes and making modifications in exercise and diet could perhaps help to reverse the process."


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9-Nov-2004


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