HOME >> MEDICINE >> NEWS
Behavioral sensitization: A new perspective on alcoholism

  • Alcoholics may drink because they get a "bigger bang" each time they drink.
  • This phenomenon is known as "behavioral sensitization."
  • Behavioral sensitization is the opposite of tolerance; it is even known as "reverse tolerance."
  • A neurochemical called MK-801 may block alcohol's sensitizing effects.
One of the ways by which people are believed to develop alcoholism is called "behavioral sensitization" to the effects of alcohol. This is another way of saying that each time someone drinks, they may find the alcohol more rewarding. In a recent study published in the March issue of Alcoholism: Clinical & Experimental Research, researchers explained how they may have found a way to "block" the increasingly rewarding effects of alcohol.

"What we've tried to show in this study," said Rosana Camarini, the study's lead author who is conducting post-doctoral research in neurology at the University of California San Francisco, "is that it may be possible to block behavioral sensitization to alcohol by using NMDA receptor antagonists. The specific one we studied is called MK-801."

Alcohol affects virtually every organ system in the body and alters the activity of most major neurochemicals. Alcohol's effects on the glutamate system are of particular interest to researchers. Glutamate acts as one of the brain's endogenous (made within the body) excitatory systems. A subtype of glutamate receptors, the n-methyl-d-aspartate (NMDA) receptor, is highly sensitive to low doses of alcohol. Evidence indicates that alcohol may interact directly with the NMDA receptor complex. Indeed, NMDA receptors may be involved in sensitization to, tolerance of, and physical dependence on a variety of drugs, including opiates, nicotine, antidepressants and alcohol. NMDA receptor antagonists - in this case, MK-801 - appear to be able to "block" some of the pleasing effec
'"/>

Contact: Rosana Camarini, Ph.D.
rosanac@itsa.ucsf.edu
510-985-3924
Alcoholism: Clinical & Experimental Research
13-Mar-2000


Page: 1 2 3 4

Related medicine news :

1. 2005 Behavioral Sciences & Health Services Research Award
2. Behavioral symptoms may indicate increased smoking risk among adolescents
3. 2004 Behavioral Sciences/Health Services Award to Helen Gift
4. NHGRI launches Social and Behavioral Research Branch
5. Behavioral therapies plus pharmacotherapies can add up to success
6. Behavioral program boosts antibody that fights breast cancer
7. Parenting CD-ROM Helps Reduce Childrens Behavioral Problems
8. Landmark Study Shows Behavioral Interventions Reduce HIV-Related Sexual Risk Behavior
9. Most Comprehensive Study Of Its Kind Shows Common Asthma Medications Dont Cause Behavioral Problems In Children, According To The Journal Pediatrics
10. Rhesus monkeys reason about perspectives of others in obtaining food
11. CT with multiplanar reconstruction gives new perspective on complex ankle fractures

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/9/2019)... ... 2019 , ... John V. Prunskis, MD., co-founder and co-Medical ... Human Services' (HHS) Pain Management Best Practices Inter-Agency Task Force (Pain Task Force) ... in Washington DC. , Hosted by the Alliance for Balanced Pain Management, the ...
(Date:12/9/2019)... ... December 09, 2019 , ... ... innovative solutions that help food and manufacturing companies engage with their workforces ... This turnkey solution helps manufacturers build a cohesive culture that is designed ...
(Date:12/8/2019)... HOUSTON (PRWEB) , ... December 07, 2019 , ... More ... according to a recent report from the American Academy of Dermatology, indicating this problem ... on an upward trend during the years to come. These dermatological conditions vary in ...
(Date:12/8/2019)... ... December 08, 2019 , ... Intelligent.com, a trusted resource ... Best Homeland Security Degree Programs for 2020. The comprehensive research guide is based ... program is evaluated based on curriculum quality, graduation rate, reputation, and post-graduate employment. ...
(Date:12/6/2019)... ... December 06, 2019 , ... ... for its innovations and excellence in patient care. On December 12th, Hartford Business ... excellence at the Health Care Heroes Awards at the Hartford Marriott. , “We ...
Breaking Medicine News(10 mins):
(Date:12/6/2019)... ... December 06, 2019 , ... ... announce an expansion in services. While Kindred Nutrition and Wellness will continue ... they are now happy to offer Individual and Family Therapy and Yoga. , ...
(Date:12/5/2019)... ... December 05, 2019 , ... ... Amazon Web Services (AWS) Public Sector Partner Program; a designation that will ... program recognizes and collaborates with partners that offer solutions and proven experience ...
(Date:12/4/2019)... ... December 04, 2019 , ... The Harm Reduction Institute (HRI) as a ... drug and alcohol rehab center and non-profit Intensive outpatient after care (IOP) ... outreach, trained, and distributed Naloxone amongst members of the own community in Orange County, ...
Breaking Medicine Technology:
Cached News: