Behavioral sensitization: A new perspective on alcoholism

ts of alcohol. In other words, MK-801 may lend itself to treatment possibilities by helping make alcohol less appealing to someone who has lost control of their drinking.

"All basic, biomedical research that addresses drug abuse," said Clyde W. Hodge, assistant professor of neurology at the University of California San Francisco, "whether that abuse is about alcohol, cocaine, or any drug, is directed toward understanding the neurobiological mechanisms that lead to addiction. Once we understand the neurobiology, hopefully we can design medications to alter some aspect of addiction.

"This study provides evidence," he continued, "that MK-801 blocks one of the addictive properties of alcohol, its sensitizing effects. From a perspective of therapeutics, it means that NMDA receptors could be a valid target for treatment."

To those familiar with the concept of tolerance, the phenomenon known as behavioral sensitization is intuitively confusing. Yet many aspects of the processes that underlie the transition from initial drinking to uncontrolled drinking remain unknown and under research. For example, studies of amphetamine and cocaine have shown that, with repeated and intermittent administration, both behavioral and neurochemical responses are progressively enhanced. This phenomenon, behavioral sensitization, contrasts with the well-known observation that repeated, frequent or continuous drug administration can lead to many diminished responses (tolerance). Indeed, behavioral sensitization is also called "reverse tolerance." Despite the potential confusion, behavioral sensitization may help explain how substances of abuse can become addicting.

"We believe that people may drink more and more because of the pleasurable and euphoric effects of alcohol," said Camarini, "and these effects increase with time. In fact, there are theories that, after time, once this phenomenon is

Contact: Rosana Camarini, Ph.D.
Alcoholism: Clinical & Experimental Research

Page: 1 2 3 4

Related medicine news :

1. 2005 Behavioral Sciences & Health Services Research Award
2. Behavioral symptoms may indicate increased smoking risk among adolescents
3. 2004 Behavioral Sciences/Health Services Award to Helen Gift
4. NHGRI launches Social and Behavioral Research Branch
5. Behavioral therapies plus pharmacotherapies can add up to success
6. Behavioral program boosts antibody that fights breast cancer
7. Parenting CD-ROM Helps Reduce Childrens Behavioral Problems
8. Landmark Study Shows Behavioral Interventions Reduce HIV-Related Sexual Risk Behavior
9. Most Comprehensive Study Of Its Kind Shows Common Asthma Medications Dont Cause Behavioral Problems In Children, According To The Journal Pediatrics
10. Rhesus monkeys reason about perspectives of others in obtaining food
11. CT with multiplanar reconstruction gives new perspective on complex ankle fractures

Post Your Comments:

(Date:1/23/2020)... LOS ANGELES (PRWEB) , ... January 23, 2020 , ... ... with Inspired Organics Brand Director, Michelle Berger and Vice President of Dairy ... options. , Inspired Organics is a company that creates organic food and snack options ...
(Date:1/23/2020)... ... January 23, 2020 , ... Merger and acquisition activity in the ... of 2019, according to data from HealthCareMandA.com. The total is the lowest reported in ... when 65 deals were announced. , One deal disclosed a price in the fourth ...
(Date:1/23/2020)... Del. (PRWEB) , ... January 23, 2020 , ... ... coaching and risk services for organizations that operate vehicle fleets in North America ... new subscriber-based e-newsletter, will be published monthly with content accessible on the company’s ...
(Date:1/23/2020)... ... , ... The Incentive Research Foundation is pleased to announce ... segments of the incentives, rewards, and recognition industry, the IRF Board of Trustees ... highlighting the power of incentive and motivational programs. The Board recently met to ...
(Date:1/22/2020)... ... January 22, 2020 , ... In Partnership with the ... dental services for low-income, underinsured individuals at its Largo, FL office on March 7th. ... x-rays , fillings , cleanings and extractions . For more ...
Breaking Medicine News(10 mins):
(Date:1/23/2020)... ... 23, 2020 , ... In the largest genetic sequencing study ... with risk for autism. The study also shows significant progress towards teasing apart ... delay, conditions which often overlap. The study results are published online January 23 ...
(Date:1/23/2020)... (PRWEB) , ... January 23, 2020 , ... ... pain have trusted Australian Dream® for effective relief. Now, the company ... relief. , Australian Dream sought to develop a new design that better communicates ...
(Date:1/23/2020)... Mass. (PRWEB) , ... January 23, 2020 , ... ... of evidence-based clinical resource tools, has announced the availability of a new decision ... Treatment Options presents several pharmacotherapeutic options to manage opioid addiction. , Opioid addiction ...
Breaking Medicine Technology:
Cached News: