Beta Blocker Significantly Improves Heart Failure Survival

An international study of almost 4,000 people with heart failure finds that adding the beta-blocker metoprolol to standard treatment increases survival by about 35 percent. The results are so positive that the study was stopped three years earlier than planned so that all participants could be offered the beta-blocker drug. Results of the study will be presented at the 71st Annual Scientific Sessions of the American Heart Association in Dallas on November 10.

"With this large study, we now know that by adding beta-blocker therapy to our standard treatments for heart failure, we can save many more lives," says Stephen Gottlieb, M.D., a cardiologist who directs the heart failure service at the University of Maryland Medical Center in Baltimore. Dr. Gottlieb, who also is an associate professor of medicine at the University of Maryland School of Medicine, was the U.S. National Co-Director of the study.

Doctors have been reluctant to give beta blockers to people with congestive heart failure, because they initially reduce the heart's pumping ability, according to Dr. Gottlieb. "However, when given carefully, starting with a very low dose and gradually increasing the dose, the long term effect is to increase cardiac function and improve survival," he adds.

Beta-blockers are routinely prescribed for several medical conditions, including hypertension. They also are recommended for patients following a heart attack.

The study, called Metoprolol CR/XL Randomized Intervention Trial in Heart Failure (Merit-HF), was conducted in the United States and 13 other countries. It was sponsored by Astra AB of Sweden, the company that manufactures metoprolol. Of the 3,991 heart failure patients in the study, 1,071 were from the United States.

The study began in February 1997 when participants were randomly assigned to receive either the beta-blocker or a placebo. The study was stopped on October 31, 1998, when

Contact: Ellen Beth Levitt
University of Maryland Medical Center

Page: 1 2

Related medicine news :

1. Two Beta-Blocker Drugs Equal In Treating Heart Failure
2. Beta-Blockers Underused In Older Patients After Heart Attacks, Major Study Of 45,000 Patients 65 Years Or Older Reveals
3. American Heart Association Comment: Tirofiban -- The Platelet Receptor Blocker For Heart Attack
4. Diuretics And Beta-Blockers Are Best Drugs To Combat High Blood Pressure, Study Finds
5. Significantly lower physical activity levels in obese adolescents contribute to continued obesity
6. Interferon Significantly Affects Metabolism Of Other Drugs Given To Cancer Patients, Finds University Of Pittsburgh Cancer Institute
7. Relaxation And Music Significantly Reduce Patients Postoperative Pain
8. Novel Therapy Significantly Reduces Spinal Fractures In Postmenopausal WomenWith Two Years Of Therapy
9. Combination Therapy Improves Chances Of Surviving Esophageal Cancer
10. Lewin Study Confirms Diabetes Treatment Centers of Americas Diabetes NetCareSM Program Improves Health Status, Reduces Medical Costs
11. New Report Demonstrates That Following Guidelines Improves Clinical Practices, Reduces Liability Costs

Post Your Comments:

(Date:7/31/2020)... ... July 31, 2020 , ... Today Hinge Health, ... expansion of clinical & technical capabilities to cover the full continuum of care ... joint health solution. , Currently, employers interested in truly solving their MSK ...
(Date:7/22/2020)... ... , ... Ocean Tomo Transactions, LLC will auction a patent ... Brock University for jurisdictions throughout North America, Europe and Asia. Ocean Tomo ... manufacturing processes of novel opioid related compositions for pain management as well as ...
(Date:7/18/2020)... (PRWEB) , ... July 17, 2020 , ... “Frozen.” It’s ... to a shoulder joint – oftentimes for unknown reasons – resulting in stiffness, persistent ... MD , an expert in treating problems of the upper limbs and joints and ...
(Date:7/18/2020)... ... July 18, 2020 , ... When the federal government extended ... opportunity for small and some bigger businesses to obtain a PPP loan. But the ... the “GIG Economy” do not realize they are eligible. , While 4.9 million ...
(Date:7/10/2020)... ... July 09, 2020 , ... CellTrak, ... behavioral health announces that Ohio Department of Medicaid has awarded CellTrak Phase 2 ... agencies in Ohio already rely on CellTrak for EVV – both as a ...
Breaking Medicine News(10 mins):
(Date:7/10/2020)... ... July 10, 2020 , ... The Dolphin Company, the ... more than 12 million guests, unveiled its new comprehensive plan of protocols and ... in all facets of the operation, safety, and health addressing COVID-19. , Experts ...
(Date:7/10/2020)... FRANCISCO, Calif. (PRWEB) , ... ... ... Pharmaceutical Review , the leading review of business and technology for the ... cover the development and manufacturing of the highest quality pharmaceutical products. ...
(Date:7/7/2020)... ... July 07, 2020 , ... To support those on the ... Change (WGC), will be providing meals to the employees of Southern Nevada Health District. ... throughout Las Vegas on Wednesday, July 8th. , When asked why the Women of ...
Breaking Medicine Technology:
Cached News: