Beta-blockers may help broader group of patients with heart problems

Doctors can see how well the left ventricle works by measuring the ejection fraction, which is the percentage of blood squeezed out of the ventricle with each heartbeat. An ejection fraction of 50 percent means the ventricle spurts out half its volume each time it contracts.

Healthy ejection fractions are 50 percent or higher; lower ejection fractions can mean heart disease. But patients may have normal ejection fractions and still have serious heart problems such as severe mitral regurgitation.

In the study, 32 percent of 869 participating mitral regurgitation patients were on a beta-blocker. Beta-blockers reduce the heart rate and the force of muscle contraction, thereby reducing oxygen demand on heart muscle.

The researchers found that beta-blockers increased patients' survival, independent of patients' age, gender, or whether they had coronary artery disease, diabetes, high blood pressure or valve surgery.

In a related poster, researchers showed the drugs' benefits to patients with diastolic heart failure-those with congestive heart failure, or CHF, who have normal ejection fraction.

Researchers studied 2,246 patients with CHF; 1,079 of them had normal ejection fractions. The patients were on a variety of CHF therapy regimens, which might include aspirin, diuretics, digoxin, ACE inhibitors and beta-blockers.

Beta-blockers were once thought risky for heart-failure patients. But the investigators found that after five years, 65 percent of patients treated with beta-blockers were alive, compared to 50 percent of those who received no beta-blockers. Beta-blocker therapy still showed a strong survival benefit after researchers adjusted for patients' age, gender, hypertension, diabetes and coronary artery disease.

Ramdas G. Pai, M.D., professor of clinical cardiovascular medicine at the Keck School and the study's senior author, explained that catecholamines-the hormones released in the body in stress s

Contact: Sarah Huoh
University of Southern California

Page: 1 2 3

Related medicine news :

1. Beta-blockers protect brain during bypass surgery
2. Beta-blockers after heart surgery show double benefits
3. Beta-blockers improve outcomes of bypass surgery
4. Existing therapies applied to new use in broader spectrum of cancer care
5. Sexual lifestyles vary among ethnic groups in Britain
6. Vaccinating school children and high risk groups is best strategy for slowing flu transmission
7. Added sugar displaces food groups lowering quality of preschooler diets
8. USC researchers highlight disparities in cancer rates among racial and ethnic groups in California
9. American ethnic groups less likely to have cholesterol controlled
10. Breast cancer in Asian Americans is rising faster than in any other ethnic group
11. Different subgroups of alcoholics respond differently to serotonin-acting medication

Post Your Comments:

(Date:11/27/2015)... ... November 27, 2015 , ... The print component of “Supporting ... Atlanta, Dallas, New York, Minneapolis, South Florida, with a circulation of approximately 250,000 ... through a vast social media strategy and across a network of top news ...
(Date:11/27/2015)... ... ... MPWH, the No.1 Herpes-only dating community in the world, revealed that over 50% of its ... 3.7 billion people under the age of 50 – or 67% of the population - ... estimates of HSV-1 infection . , "The data shocks us highly!" said Michelle Li, ...
(Date:11/27/2015)... Wilmington, DE (PRWEB) , ... November 27, 2015 ... ... a member of the well-respected Microsoft Dynamics SL User Group (MSDSLUG). Recognized as ... is an independent group of Microsoft Dynamics SL software users, partners, industry experts ...
(Date:11/27/2015)... MINNEAPOLIS, Minn. (PRWEB) , ... November 27, 2015 ... ... you start failing. Secura Consultants has prided itself for not only fulfilling the ... best income protection solutions at an affordable price and providing top-tier customer service. ...
(Date:11/27/2015)... Los Angeles, CA (PRWEB) , ... November 27, 2015 , ... ... the Commission on Accreditation of Allied Health Education Programs (CAAHEP) awarded accreditation to its ... exclusive list of CAAHEP accredited colleges, as only one of twelve colleges and universities ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... Research and Markets ( http://www.researchandmarkets.com/research/lttqph/asia_pacific ) has announced ... Outlook to 2019 - Rise in Cardiac Disorders and Growing ... to their offering. Boston ... scientific and others. --> The market ... Boston scientific and others. ...
(Date:11/26/2015)... Nov. 26, 2015 Research and Markets ... the "2016 Future Horizons and Growth Strategies ... Supplier Shares, Country Segment Forecasts, Competitive Intelligence, Emerging ... --> --> This ... the Japanese therapeutic drug monitoring market, including emerging ...
(Date:11/26/2015)... 2015 http://www.researchandmarkets.com/research/4gmqdf/2016_future ... the  "2016 Future Horizons and Growth ... Testing Market: Supplier Shares, Competitive Intelligence, ... --> http://www.researchandmarkets.com/research/4gmqdf/2016_future ) has ... Future Horizons and Growth Strategies in ...
Breaking Medicine Technology:
Cached News: