HOME >> MEDICINE >> NEWS
Black Teen-Agers With Severe Asthma Are Three Times More Likely Than White Teens To Be Steroid Resistant

DENVER- Black teen-agers are three times more likely than white teen-agers to have steroid resistant asthma, research at National Jewish Medical and Research Center has found.

"Our results suggest that children with steroid-resistant asthma are more likely to be African-American, to have required treatment with oral steroids at an earlier age and to require larger amounts of oral steroids for only marginal control of their asthma," said Joseph Spahn, M.D., a pediatric allergist and director of the Immunopharmacology Lab at National Jewish.

Other recent epidemiological studies have shown that blacks with asthma are sicker and have a higher mortality rate than whites with asthma. Doctors at National Jewish now are trying to determine whether blacks have a more vigorous immune response to airway inflammation--which means that higher doses of steroids must be used to control inflammation--or a poor response to steroids secondary to a genetic resistance to the drugs.

"The theory is that with ongoing airway inflammation you get worsening asthma and diminished steroid sensitivity," Dr. Spahn said.

This study of 164 teen-agers treated at National Jewish also showed that 25 percent of the group was steroid resistant. Children with less than a 15 percent improvement in lung function following a "burst" of inhaled steroids--high doses over seven days--were considered steroid resistant.

"Twenty-five percent of the kids admitted to National Jewish have steroid-resistant asthma, which is much greater than anyone thought," Dr. Spahn said.

It has been estimated that only one-tenth of a percent of the 15 million people in the United States with asthma are steroid resistant. About 5 million children in the United States have asthma.

The study, published in the Journal of Allergy and Clinical Immunology, is the first to examine steroid-resistant asthma in children.

A person with steroid-resistant asthma receives limited reduction in airway inflammation
'"/>

Contact: Jordan Gruener
gruenerj@njc.org
303-398-1002
National Jewish Medical and Research Center
23-Jul-1998


Page: 1 2

Related medicine news :

1. Blacks less likely to get expensive, newer heart treatments
2. Blacks in the South have greater risk of dying from stroke
3. The American Academy of Nurse Practitioners and Blackwell Publishing announce partnership
4. Blacks and poor more likely to donate than receive many types of transplant organs
5. Blacks less likely to start smoking, less likely to quit
6. Blacks report better sexual, urinary function after prostate surgery than whites
7. Black and Hispanic patients wait longer for heart attack treatment
8. Black women with high blood pressure during pregnancy have higher homocysteine levels
9. ISSIR launches The Journal of Sexual Medicine with Blackwell
10. Blackwell Publishing acquires BMJ Books
11. Black men less likely to be treated for aggressive prostate cancer, UMHS study finds

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... 2017 , ... While it’s often important to take certain medications during the ... Texas, has identified a solution. , She developed a prototype for MOTION LIGHT-UP PILL ... it eliminates the need to turn on a light when taking medication during the ...
(Date:10/13/2017)... ... 13, 2017 , ... Lori R. Somekh, founder of the Law Office ... of elder law and special needs planning attorneys. “Membership in ElderCounsel helps our office ... forum to network with elder law attorneys nationwide,” said Somekh. , ElderCounsel ...
(Date:10/13/2017)... ... October 13, 2017 , ... Global Healthcare Management’s 4th Annual ... in Milford, NJ. This free event, sponsored by Global Healthcare Management’s CEO, Jon ... fun run is geared towards children of all ages; it is a non-competitive, non-timed ...
(Date:10/13/2017)... ... ... “America On The Brink”: the Christian history of the United States and the ... published author, William Nowers. Captain Nowers and his wife, Millie, have six children, ... in the Navy. Following his career as a naval aviator and carrier pilot, ...
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... IsoComforter, Inc. ... products, announced today the introduction of an innovative new design of the shoulder pad. ... so you get maximum comfort while controlling your pain while using cold therapy. By ...
Breaking Medicine News(10 mins):
(Date:9/28/2017)... Hill-Rom Holdings, Inc. (NYSE: HRC), will host its fiscal ... Friday, November 3, 2017, beginning at 7:00 a.m. (CDT) ... a.m. (CDT) / 9:30 a.m. (EDT). In ... guidance for 2018, Hill-Rom executives will also highlight the ... long-range financial outlook through 2020. ...
(Date:9/25/2017)... , Sept. 25, 2017   Montrium ... Master File solutions, today—from the IQPC Trial Master ... , NL)—announced that EastHORN Clinical Services has ... clinical programs and TMF management. EastHORN, a leading ... eTMF platform to increase transparency to enable greater ...
(Date:9/22/2017)... , Sept. 22, 2017 AVACEN Medical ... device is now successfully helping those with the widespread ... Fibromyalgia diagnosed Amanda in Essex, England ... and washing my hair, experiencing no sleep at all, ... painful spasm… I cannot recommend [the AVACEN 100] enough, ...
Breaking Medicine Technology:
Cached News: