HOME >> MEDICINE >> NEWS
Black Teen-Agers With Severe Asthma Are Three Times More Likely Than White Teens To Be Steroid Resistant

DENVER- Black teen-agers are three times more likely than white teen-agers to have steroid resistant asthma, research at National Jewish Medical and Research Center has found.

"Our results suggest that children with steroid-resistant asthma are more likely to be African-American, to have required treatment with oral steroids at an earlier age and to require larger amounts of oral steroids for only marginal control of their asthma," said Joseph Spahn, M.D., a pediatric allergist and director of the Immunopharmacology Lab at National Jewish.

Other recent epidemiological studies have shown that blacks with asthma are sicker and have a higher mortality rate than whites with asthma. Doctors at National Jewish now are trying to determine whether blacks have a more vigorous immune response to airway inflammation--which means that higher doses of steroids must be used to control inflammation--or a poor response to steroids secondary to a genetic resistance to the drugs.

"The theory is that with ongoing airway inflammation you get worsening asthma and diminished steroid sensitivity," Dr. Spahn said.

This study of 164 teen-agers treated at National Jewish also showed that 25 percent of the group was steroid resistant. Children with less than a 15 percent improvement in lung function following a "burst" of inhaled steroids--high doses over seven days--were considered steroid resistant.

"Twenty-five percent of the kids admitted to National Jewish have steroid-resistant asthma, which is much greater than anyone thought," Dr. Spahn said.

It has been estimated that only one-tenth of a percent of the 15 million people in the United States with asthma are steroid resistant. About 5 million children in the United States have asthma.

The study, published in the Journal of Allergy and Clinical Immunology, is the first to examine steroid-resistant asthma in children.

A person with steroid-resistant asthma receives limited reduction in airway inflammation
'"/>

Contact: Jordan Gruener
gruenerj@njc.org
303-398-1002
National Jewish Medical and Research Center
23-Jul-1998


Page: 1 2

Related medicine news :

1. Blacks less likely to get expensive, newer heart treatments
2. Blacks in the South have greater risk of dying from stroke
3. The American Academy of Nurse Practitioners and Blackwell Publishing announce partnership
4. Blacks and poor more likely to donate than receive many types of transplant organs
5. Blacks less likely to start smoking, less likely to quit
6. Blacks report better sexual, urinary function after prostate surgery than whites
7. Black and Hispanic patients wait longer for heart attack treatment
8. Black women with high blood pressure during pregnancy have higher homocysteine levels
9. ISSIR launches The Journal of Sexual Medicine with Blackwell
10. Blackwell Publishing acquires BMJ Books
11. Black men less likely to be treated for aggressive prostate cancer, UMHS study finds

Post Your Comments:
(Date:10/30/2014)... Steven Reinberg HealthDay Reporter ... therapy to men with prostate cancer who also have certain ... heart-related cause, a new study suggests. , , The therapy in ... prostate cancer to reduce levels of male hormones to prevent ... in the current research, this hormone therapy was linked to ...
(Date:10/30/2014)... October 30, 2014 Dr. Joseph Furlin MD, ... website for his practices; OB GYN in Melrose Park, ... This website contains important information about each of the ... as downloadable patient forms in English and Spanish. The ... service pages on the website provide Dr. Furlin’s patients with ...
(Date:10/30/2014)... Beach, California (PRWEB) October 30, 2014 ... nutrtion bars are now available through a unique service ... online site designed to empower the everyday athlete. The ... worlds best athletes and created a system to pass ... excited to see REV’D® is now available on The ...
(Date:10/30/2014)... 30, 2014 Sound Telecom, a leader in ... will assist people any time they wonder, “Should I use ... answer by leading them through a series of yes or ... initial query. , There are many considerations and scenarios that ... an answering service . This decision infographic serves as ...
(Date:10/30/2014)... Dennis Thompson HealthDay Reporter ... lots of milk could be bad for your health, a ... calcium in milk can help strengthen bones and prevent osteoporosis. ... to recommend milk as part of a healthy diet. ... milk did not protect men or women from bone fractures, ...
Breaking Medicine News(10 mins):Health News:Hormone Therapy May Up Heart-Related Deaths in Some Prostate Cancer Patients 2Health News:Hormone Therapy May Up Heart-Related Deaths in Some Prostate Cancer Patients 3Health News:Dr. Joseph Furlin Launches New Website with Information about Care Services 2Health News:Nutrition Experts at TheFeed.com Get REV'D 2Health News:Nutrition Experts at TheFeed.com Get REV'D 3Health News:Sound Telecom Produces Decision Infographic to Aid Businesses 2Health News:Is Milk Your Friend or Foe? 2Health News:Is Milk Your Friend or Foe? 3
(Date:10/30/2014)... 30, 2014  Zimmer Holdings, Inc. (NYSE: ... executive leadership team and organizational structure of the combined ... also announced that the combined organization will leverage the ... Zimmer Biomet, with the new brand to be rolled ... the merger.  The future leadership team is committed to ...
(Date:10/30/2014)... -- CVS Health (NYSE: CVS ) announced today ... regional health systems to enhance access to high-quality, affordable health ... Health System in Alabama ; Community Health ... Pennsylvania , Northwest Medical Center, including Oro Valley ... in Tennessee ; and Premier Health in ...
(Date:10/30/2014)... 2014  CytRx Corporation (NASDAQ: CYTR ... in oncology, today announced an upcoming presentation highlighting ... aldoxorubicin.  The presentation, titled, "Drug Conjugates Bind Covalently ... by Sant P. Chawla , M.D., F.R.A.C.P., ... investigator of the Company,s ongoing global, pivotal Phase ...
Breaking Medicine Technology:Zimmer Announces Executive Leadership Team and New Name of Combined Company Following Closing 2Zimmer Announces Executive Leadership Team and New Name of Combined Company Following Closing 3Zimmer Announces Executive Leadership Team and New Name of Combined Company Following Closing 4Zimmer Announces Executive Leadership Team and New Name of Combined Company Following Closing 5Zimmer Announces Executive Leadership Team and New Name of Combined Company Following Closing 6Zimmer Announces Executive Leadership Team and New Name of Combined Company Following Closing 7Zimmer Announces Executive Leadership Team and New Name of Combined Company Following Closing 8Zimmer Announces Executive Leadership Team and New Name of Combined Company Following Closing 9CVS Health Announces New Clinical Affiliations with Leading Regional Health Systems 2CVS Health Announces New Clinical Affiliations with Leading Regional Health Systems 3CVS Health Announces New Clinical Affiliations with Leading Regional Health Systems 4CytRx Announces Oral Presentation at 2014 Chemotherapy Foundation Symposium 2CytRx Announces Oral Presentation at 2014 Chemotherapy Foundation Symposium 3CytRx Announces Oral Presentation at 2014 Chemotherapy Foundation Symposium 4
Cached News: