HOME >> MEDICINE >> NEWS
Blood dilution during bypass surgery associated with kidney damage



Receiptents of nanotechnology funding from the National Nanotechnology Initiative.

DURHAM, N.C. -- When physicians routinely "thin" the blood of patients undergoing coronary artery bypass surgery in order to place them on the heart-lung machine, they may be causing more damage to the kidneys and other organs than previously appreciated, according to a new study by Duke University Medical Center researchers.

For years moderate dilution of the blood has been thought to protect the kidneys from damage, but the Duke researchers found in their study of more than 1,400 bypass patients that dilution to the lower levels of accepted ranges is associated with measurable kidney damage. The Duke team published the results of its study in the September 2003 issue of the Annals of Thoracic Surgery.

In order to safely operate on a non-beating heart, physicians attach the body to a heart-lung machine, which takes over for the stopped heart in circulating oxygen-rich blood throughout the body. To prime the pump, physicians add fluid -- usually a balanced saline solution -- to the circuit to fill the tubing and pumping chambers of the machine.

This additional fluid lowers the percentage of oxygen-carrying red blood cells in the blood, a measurement known as hematocrit. Normal hematocrit ranges from 36 to 40 percent. During bypass surgeries, the hematocrit can range from 22 to 26 percent, with even lower percentages being commonly attained at different points during the operation.

"Using hematocrit as a tool to assess a patient's anemia, we found that the lowest hematocrit achieved during the bypass procedure was significantly associated with acute kidney damage," said Duke anesthesiologist and study leader Mark Stafford-Smith, M.D. "Furthermore, we f
'"/>

Contact: Richard Merritt
merri006@mc.duke.edu
919-684-4148
Duke University Medical Center
3-Sep-2003


Page: 1 2 3 4

Related medicine news :

1. Blood pressure treatment could cut risk of strokes and heart attacks
2. Blood protein predicts risk of heart attack
3. Blood transplants may be more harmful than bone marrow transplants in pediatric leukemia patients
4. Blood pressure drugs may slow deterioration of Alzheimers
5. Blood pressure control poor in elderly, says Northwestern researcher
6. Blood pressure for children and adolescents on the rise
7. Blood pressure drug helps delay ischemic brain damage in stroke patients
8. Blood screen may help cancer patients thwart radiation side effects, say Stanford researchers
9. Blood test for liver cancer risk
10. Blood-forming stem cells fail to repair heart muscle in Stanford study
11. Blood test heralds speedy stroke diagnoses

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/25/2016)... ... June 25, 2016 , ... Austin residents seeking Mohs surgery services, can now ... and to Dr. Russell Peckham for medical and surgical dermatology. , Dr. Dorsey brings ... The selective fellowship in Mohs Micrographic Surgery completed by Dr. Dorsey was under the ...
(Date:6/25/2016)... ... , ... As a lifelong Southern Californian, Dr. Omkar Marathe earned his Bachelors ... Geffen School of Medicine at UCLA. He trained in Internal Medicine at Scripps Green ... hematology/oncology at the UCLA-Olive View-Cedars Sinai program where he had the opportunity to train ...
(Date:6/24/2016)... CA (PRWEB) , ... June 24, 2016 , ... A ... procedures that most people are unfamiliar with. The article goes on to state that ... but also many of these less common operations such as calf and cheek reduction. ...
(Date:6/24/2016)... ... 24, 2016 , ... The Pulmonary Hypertension Association (PHA) learned ... receive two significant new grants to support its work to advance research and ... by recognizing patients, medical professionals and scientists for their work in fighting pulmonary ...
(Date:6/24/2016)... NY (PRWEB) , ... June 24, 2016 , ... Topical BioMedics, Inc, makers of Topricin ... companies that call for a minimum wage raise to $12 an hour by 2020 and ... This will restore the lost value of the minimum wage, assure the wage floor does ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... Calif. , June 24, 2016  American Respiratory Labs (ARL), ... is now able to perform sophisticated lung assessments in patients, homes, ... , Inc. Patients are no longer limited to ... EasyOne PRO ® , ARL patients like Jeanne R. of ... in the comfort of her own home. ...
(Date:6/24/2016)... , June 24, 2016  Arkis BioSciences, ... less invasive and more durable cerebrospinal fluid treatments, ... funding.  The Series-A funding is led by Innova ... Fund, and other private investors.  Arkis, new financing ... instrumentation and the market release of its in-licensed ...
(Date:6/23/2016)... 23, 2016  In a startling report released today, National ... by lacking a comprehensive, proven plan to eliminate prescription opioid overdoses. ... of how states are tackling the worst drug crisis in recorded ... – Kentucky , New Mexico ... . Of the 28 failing states, three – Michigan ...
Breaking Medicine Technology:
Cached News: