HOME >> MEDICINE >> NEWS
Blood dilution during bypass surgery associated with kidney damage



Receiptents of nanotechnology funding from the National Nanotechnology Initiative.

DURHAM, N.C. -- When physicians routinely "thin" the blood of patients undergoing coronary artery bypass surgery in order to place them on the heart-lung machine, they may be causing more damage to the kidneys and other organs than previously appreciated, according to a new study by Duke University Medical Center researchers.

For years moderate dilution of the blood has been thought to protect the kidneys from damage, but the Duke researchers found in their study of more than 1,400 bypass patients that dilution to the lower levels of accepted ranges is associated with measurable kidney damage. The Duke team published the results of its study in the September 2003 issue of the Annals of Thoracic Surgery.

In order to safely operate on a non-beating heart, physicians attach the body to a heart-lung machine, which takes over for the stopped heart in circulating oxygen-rich blood throughout the body. To prime the pump, physicians add fluid -- usually a balanced saline solution -- to the circuit to fill the tubing and pumping chambers of the machine.

This additional fluid lowers the percentage of oxygen-carrying red blood cells in the blood, a measurement known as hematocrit. Normal hematocrit ranges from 36 to 40 percent. During bypass surgeries, the hematocrit can range from 22 to 26 percent, with even lower percentages being commonly attained at different points during the operation.

"Using hematocrit as a tool to assess a patient's anemia, we found that the lowest hematocrit achieved during the bypass procedure was significantly associated with acute kidney damage," said Duke anesthesiologist and study leader Mark Stafford-Smith, M.D. "Furthermore, we f
'"/>

Contact: Richard Merritt
merri006@mc.duke.edu
919-684-4148
Duke University Medical Center
3-Sep-2003


Page: 1 2 3 4

Related medicine news :

1. Blood pressure treatment could cut risk of strokes and heart attacks
2. Blood protein predicts risk of heart attack
3. Blood transplants may be more harmful than bone marrow transplants in pediatric leukemia patients
4. Blood pressure drugs may slow deterioration of Alzheimers
5. Blood pressure control poor in elderly, says Northwestern researcher
6. Blood pressure for children and adolescents on the rise
7. Blood pressure drug helps delay ischemic brain damage in stroke patients
8. Blood screen may help cancer patients thwart radiation side effects, say Stanford researchers
9. Blood test for liver cancer risk
10. Blood-forming stem cells fail to repair heart muscle in Stanford study
11. Blood test heralds speedy stroke diagnoses

Post Your Comments:
(Date:7/2/2015)... ... July 02, 2015 , ... Six months ahead of ... cross-country walk to raise awareness and money for the Pulmonary Hypertension Association (PHA). ... at PHA’s headquarters near Washington, D.C. by mid-September. He left Glasgow, Mont. yesterday morning ...
(Date:7/2/2015)... (PRWEB) , ... July 02, ... ... wound therapy (NPWT) - pipeline review 2015” provides comprehensive information on the ... development. Complete report on negative pressure wound therapy (NPWT) with 22 market ...
(Date:7/2/2015)... ... ... Time Pain Relief (RTPR), makers of the popular rub-on pain relief lotion and products, ... The Fifth Annual Big Sky Professional Bull Riders Event being held this month at Big ... relief lotion and products at the family friendly event that features two days of bull ...
(Date:7/2/2015)... ... July 02, 2015 , ... Five individuals from ... in Anniston for specialized disaster training. The team – composed of four clinicians ... California Hospital Association who attended the training, which is dedicated to preparing first ...
(Date:7/2/2015)... ... July 02, 2015 , ... B. ... has been retained to lead a national chief operating officer recruitment ... firms in the healthcare industry, B. E. Smith has recently placed more than ...
Breaking Medicine News(10 mins):Health News:79-Year-old ‘Pacing Parson’ Passes 1,000-Mile Mark in Cross-Country Walk for Pulmonary Hypertension Association 2Health News:79-Year-old ‘Pacing Parson’ Passes 1,000-Mile Mark in Cross-Country Walk for Pulmonary Hypertension Association 3Health News:Negative Pressure Wound Therapy (System, Wound Care, Tissue Cooling NPWT) Pipeline Review 2015 Market Research Report Available at RnRMarketResearch.com 2Health News:Negative Pressure Wound Therapy (System, Wound Care, Tissue Cooling NPWT) Pipeline Review 2015 Market Research Report Available at RnRMarketResearch.com 3Health News:Negative Pressure Wound Therapy (System, Wound Care, Tissue Cooling NPWT) Pipeline Review 2015 Market Research Report Available at RnRMarketResearch.com 4Health News:Real Time Pain Relief Sponsors The Fifth Annual Big Sky Professional Bull Riders Event at Big Sky Town Center in July 2Health News:Real Time Pain Relief Sponsors The Fifth Annual Big Sky Professional Bull Riders Event at Big Sky Town Center in July 3Health News:Team from Loma Linda University Health Receives Specialized Disaster Training at FEMA’s Center for Domestic Preparedness 2Health News:Team from Loma Linda University Health Receives Specialized Disaster Training at FEMA’s Center for Domestic Preparedness 3Health News:Nicklaus Children’s Hospital Retains B. E. Smith to Recruit New Chief Operating Officer 2Health News:Nicklaus Children’s Hospital Retains B. E. Smith to Recruit New Chief Operating Officer 3
(Date:7/2/2015)... June 25, 2015 ... announced the addition of the "2015 ... Global Challenges, Emerging Technologies, Competitive Landscape" ... New Frontiers in Clinical Chemistry and Immunodiagnostics: ... a new seven-country strategic analysis of major ...
(Date:7/2/2015)... China , 2 de julio de 2015 /PRNewswire/ ... de ADN de alto rendimiento en ... el American College of Pathologists (CAP). La instalación de BGI ... primer laboratorio de secuenciación de próxima generación que recibe ... cubriendo el más alto estándar en prácticas de laboratorio ...
(Date:7/2/2015)... South Korea, July 2, 2015 ALPINION MEDICAL SYSTEMS ... E-CUBE Series ultrasound system. Developed to enhance user experience ... the E-CUBE 15 EX produces superb image quality. With ... in women,s health, general imaging, and shared service applications. ... latest in the renowned E-CUBE Series, the E-CUBE 15 ...
Breaking Medicine Technology:New Frontiers in 2015 Global Clinical Chemistry and Immunodiagnostics Market: Challenges, Emerging Technologies, Competitive Landscape 2BGI recibe la acreditación del College of American Pathologists (CAP) 2E-CUBE 15 EX from ALPINION Enhances User Experience and Patient Care 2E-CUBE 15 EX from ALPINION Enhances User Experience and Patient Care 3
Cached News: