Receiptents of nanotechnology funding from the National Nanotechnology Initiative.
DURHAM, N.C. -- When physicians routinely "thin" the blood of patients undergoing coronary artery bypass surgery in order to place them on the heart-lung machine, they may be causing more damage to the kidneys and other organs than previously appreciated, according to a new study by Duke University Medical Center researchers.
For years moderate dilution of the blood has been thought to protect the kidneys from damage, but the Duke researchers found in their study of more than 1,400 bypass patients that dilution to the lower levels of accepted ranges is associated with measurable kidney damage. The Duke team published the results of its study in the September 2003 issue of the Annals of Thoracic Surgery.
In order to safely operate on a non-beating heart, physicians attach the body to a heart-lung machine, which takes over for the stopped heart in circulating oxygen-rich blood throughout the body. To prime the pump, physicians add fluid -- usually a balanced saline solution -- to the circuit to fill the tubing and pumping chambers of the machine.
This additional fluid lowers the percentage of oxygen-carrying red blood cells in the blood, a measurement known as hematocrit. Normal hematocrit ranges from 36 to 40 percent. During bypass surgeries, the hematocrit can range from 22 to 26 percent, with even lower percentages being commonly attained at different points during the operation.
"Using hematocrit as a tool to assess a patient's anemia, we found that the lowest hematocrit achieved during the bypass procedure was significantly associated with acute kidney damage," said Duke anesthesiologist and study leader Mark Stafford-Smith, M.D. "Furthermore, we fPage: 1 2 3 4
Contact: Richard Merritt
Duke University Medical Center
Related medicine news :
1. Blood pressure treatment could cut risk of strokes and heart attacks
2. Blood protein predicts risk of heart attack
3. Blood transplants may be more harmful than bone marrow transplants in pediatric leukemia patients
4. Blood pressure drugs may slow deterioration of Alzheimers
5. Blood pressure control poor in elderly, says Northwestern researcher
6. Blood pressure for children and adolescents on the rise
7. Blood pressure drug helps delay ischemic brain damage in stroke patients
8. Blood screen may help cancer patients thwart radiation side effects, say Stanford researchers
9. Blood test for liver cancer risk
10. Blood-forming stem cells fail to repair heart muscle in Stanford study
11. Blood test heralds speedy stroke diagnoses
(Date:11/26/2014)... 25, 2014 (HealthDay News) -- Parents need to take ... concussions, an expert warns. Parents must make sure ... standard, Dr. David Dodick, chair of the American Migraine ... Clinic College of Medicine in Scottsdale, Ariz. in an ... release. Any coach involved with teens sports needs ...
(Date:11/24/2014)... 24, 2014 Global electrophysiology devices ... by 2020, according to a new study by ... cardiac arrhythmias clubbed with growing global geriatric population ... Though still in the budding stage, the electrophysiology ... usage rates in the recent times, with physicians ...
(Date:11/24/2014)... Residents of retirement communities in Ohio and ... GOT TALENT, an annual online talent competition and showcase ... classic crooners, to seniors partying on a “night on ... living young. , “SENIORS GOT TALENT, while still having ... has always been about highlighting the vibrancy of being ...
(Date:11/24/2014)... Westbury, New York (PRWEB) November 24, 2014 ... recently contacted by the Family and Children's Association ... products such as soap, shampoo, mouthwash and other such ... senior citizens who are home bound, living in nursing ... are intended to greatly enhance the well being of ...
(Date:11/24/2014)... 2014 SafeHandles™ announced that they will ... Ed Begley Jr, airing via Discovery Channel. Dates and ... a passive, non-invasive, replaceable, and affordable germ protective device. ... shrinkable sleeves and adhesives to promote hand hygiene in ... core of SafeHandles is the desire to make a ... Breaking Medicine News(10 mins):Health News:Parents Need to Take Lead on Teen Concussion Prevention 2Health News:Electrophysiology Devices Market Worth Forecasted To Reach $6.19 Billion By 2020: Grand View Research, Inc. 2Health News:Electrophysiology Devices Market Worth Forecasted To Reach $6.19 Billion By 2020: Grand View Research, Inc. 3Health News:Electrophysiology Devices Market Worth Forecasted To Reach $6.19 Billion By 2020: Grand View Research, Inc. 4Health News:Nursing Homes & Assisted Living Retirement Communities Enter Seniors Guide's Seniors Got Talent 2Health News:Nursing Homes & Assisted Living Retirement Communities Enter Seniors Guide's Seniors Got Talent 3Health News:The Holiday Inn Westbury - Long Island gives back to the local Long Island community, and also goes beyond borders to assist those in need during the 2014 Holiday Season 2Health News:The Holiday Inn Westbury - Long Island gives back to the local Long Island community, and also goes beyond borders to assist those in need during the 2014 Holiday Season 3Health News:New Episode of Innovations TV Series to Feature SafeHandles™ 2
(Date:11/26/2014)... , Nov. 25, 2014 Halozyme Therapeutics, Inc. (NASDAQ: ... Jaffray Healthcare Conference in New York ... PDT . Dr. Helen Torley , President and ... The presentation will be webcast through the "Investors" section of ... will be made available for 90 days following the event. ...
(Date:11/24/2014)... (NYSE: CRY ), a leading medical device and ... today that it will participate in the upcoming 26 th ... 2014 at The New York Palace Hotel in ... of the Company,s presentation is scheduled to begin at 1:30 ... by Pat Mackin , President and Chief Executive Officer.The ...
(Date:11/24/2014)... Nov. 24, 2014 /PRNewswire/ - Milestone Pharmaceuticals, Inc. today ... in Melbourne, Australia of ... potential treatment of paroxysmal supraventricular tachycardia (PSVT). The ... was well tolerated at single doses up to ... profile, desirable PK properties including rapid onset, and ... Breaking Medicine Technology:Halozyme Therapeutics To Present At The Piper Jaffray Healthcare Conference 2CryoLife to Present at 26th Annual Piper Jaffray Healthcare Conference 2CryoLife to Present at 26th Annual Piper Jaffray Healthcare Conference 3Milestone Announces Positive Phase 1 Data for MSP-2017; Supports Advancement into Phase 2 in PSVT Patients 2Milestone Announces Positive Phase 1 Data for MSP-2017; Supports Advancement into Phase 2 in PSVT Patients 3