Blood protein may be important predictor of future cardiovascular attack

PITTSBURGH, Feb. 16 A blood protein called serum amyloid alpha (SAA) may be an important predictor of future cardiovascular attack, according to research from the multi-center Women's Ischemia Syndrome Evaluation (WISE) Study. The study the first to find a strong relationship between SAA, which is made in response to inflammation, and coronary artery disease in women is being published in the Feb. 17 edition of Circulation, the journal of the American Heart Association.

"Some doctors are now adding C-reactive protein (CRP) to patient lipid profiles because of past study findings that high levels of CRP are predictive of heart attack and other cardiovascular events such as stroke," said B. Delia Johnson, Ph.D., epidemiology faculty research associate at the University of Pittsburgh's Graduate School of Public Health and the study's first author. "Elevated levels of SAA also appear to be highly associated with a risk of future heart attack or stroke, but key differences in the ways CRP and SAA behave may mean that SAA also has an important predictive value for adverse cardiac events, especially in the short term."

The study included 705 women who had been referred to specialists for angiography for suspected coronary artery blockage. Participants had blood tests for SAA and CRP levels as well as a thorough angiographic assessment and were followed for three years.

"Both SAA and CRP levels were associated with a broad range of risk factors for heart disease," said Dr. Johnson. "After adjusting for other risk factors, we found that SAA levels were independently associated with active disease and also highly predictive of short-term future adverse cardiovascular events."

SAA and CRP are in a family of blood proteins that are manufactured in response to inflammation or infection. They seek out and repair tissue damage and help to protect against permanent injury.

Study results are consistent with current scientific thinkin

Contact: Michele Baum
University of Pittsburgh Medical Center

Page: 1 2

Related medicine news :

1. Blood pressure treatment could cut risk of strokes and heart attacks
2. Blood protein predicts risk of heart attack
3. Blood transplants may be more harmful than bone marrow transplants in pediatric leukemia patients
4. Blood pressure drugs may slow deterioration of Alzheimers
5. Blood pressure control poor in elderly, says Northwestern researcher
6. Blood pressure for children and adolescents on the rise
7. Blood pressure drug helps delay ischemic brain damage in stroke patients
8. Blood screen may help cancer patients thwart radiation side effects, say Stanford researchers
9. Blood test for liver cancer risk
10. Blood-forming stem cells fail to repair heart muscle in Stanford study
11. Blood test heralds speedy stroke diagnoses

Post Your Comments:

(Date:8/31/2020)... ... , ... Just found out your dear friend has cancer? , It’s hard to hear your ... shares their diagnosis. Once the shock wears off, the questions and fears can be overwhelming. ... best ways to help? Words are failing me. I’m scared. I want to DO something. ...
(Date:8/31/2020)... ... August 31, 2020 , ... Colorado State University Global (CSU ... affordable online education – is proud to announce its new master’s degree in ... its kind in the nation, the 60-credit hour program is designed to provide ...
(Date:8/31/2020)... ... August 31, 2020 , ... In an effort to give back to ... 10 percent of each hotel room booked with a special new rate code to ... Indiana (RMHC-CNI) , effective immediately. Donations will be applied to any room type, ...
(Date:8/28/2020)... ... 28, 2020 , ... Ernst & Young LLP (EY US) ... Of The Year® 2020 Florida Award finalist. Now in its 34th year, the ... growth and prosperity as they build and sustain successful businesses that transform our ...
(Date:8/28/2020)... (PRWEB) , ... August 28, 2020 , ... Integrated ... Miami is the first Florida school to deploy its breakthrough Mobile Biodefense Indoor Air ... airborne COVID-19. True North Classical Academy plans to fully reopen equipped with the filtration ...
Breaking Medicine News(10 mins):
(Date:9/1/2020)... ... September 01, 2020 , ... While coronavirus cases continue to increase across ... and community organizations remain closed. Because about 80% of blood donations are made at ... blood donors and blood drive hosts to ensure blood products are readily available for ...
(Date:8/31/2020)... (PRWEB) , ... August 31, 2020 , ... If you live in New York City ... real estate part makes sense, it’s the law of supply and demand, but are plastic ... has a significant percentage of their patients that make the four-hour trip to have ...
(Date:8/28/2020)... (PRWEB) , ... August 28, 2020 , ... Dr. ... reproductive and endoscopic surgeon and serves as a clinical professor in the Department of ... of the American Laparoscopy Society & Pacific Coast Reproductive Society and is a Clinical ...
Breaking Medicine Technology:
Cached News: