HOME >> MEDICINE >> NEWS
Blood transplants may be more harmful than bone marrow transplants in pediatric leukemia patients

Alexandria, VA-A new study has shown for the first time that transplantation of peripheral blood stem cells (PBSC) from sibling donors may be more harmful than bone marrow in pediatric leukemia patients.

Researchers from the International Bone Marrow Transplant Registry (IBMTR) found that patients undergoing PBSC transplants were more likely to die of transplant-related causes than those who underwent bone marrow transplants. It is estimated that nearly 30% of transplants from sibling donors in pediatric patients now use peripheral blood stem cells. The study and an accompanying editorial will be published November 1 in the Journal of Clinical Oncology (JCO).

"Our data support the use of bone marrow for transplantation in these patients when a matched sibling donor is available," said Mary Eapen, MBBS, MS, Assistant Professor at the Medical College of Wisconsin and lead author of the study. "The higher rates of mortality observed after PBSC transplantation compared to bone marrow transplantation should serve as a cautionary note, and underscore the urgent need for a properly designed clinical trial to define the role, if any, of donor peripheral blood stem cell transplantation in children."

Background

Leukemia is cancer of the bone marrow. Bone marrow transplants involve the collection from the donor of "hematopoietic" stem cells - immature cells found in the bone marrow that mature into red blood cells, white blood cells, and platelets. Doctors have traditionally treated children with leukemia using bone marrow donated from a sibling when available, or from an unrelated volunteer donor. Another approach is peripheral blood stem cell (PBSC) transplantation, in which these stem cells are collected from the donor's blood, rather than directly from their bone marrow.

In both types of transplantation, the patient's cancerous bone marrow is destroyed with high doses of chemotherapy or radiation. Then bone marrow or pe
'"/>

Contact: Danielle Potuto
potutod@asco.org
703-519-1422
American Society of Clinical Oncology
1-Nov-2004


Page: 1 2 3

Related medicine news :

1. Blood pressure treatment could cut risk of strokes and heart attacks
2. Blood protein predicts risk of heart attack
3. Blood pressure drugs may slow deterioration of Alzheimers
4. Blood pressure control poor in elderly, says Northwestern researcher
5. Blood pressure for children and adolescents on the rise
6. Blood pressure drug helps delay ischemic brain damage in stroke patients
7. Blood screen may help cancer patients thwart radiation side effects, say Stanford researchers
8. Blood test for liver cancer risk
9. Blood-forming stem cells fail to repair heart muscle in Stanford study
10. Blood test heralds speedy stroke diagnoses
11. Blood pressure may predict recurrent cardiovascular events in women

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/23/2020)... LOS ANGELES (PRWEB) , ... January 23, 2020 , ... ... with Inspired Organics Brand Director, Michelle Berger and Vice President of Dairy ... options. , Inspired Organics is a company that creates organic food and snack options ...
(Date:1/23/2020)... ... January 23, 2020 , ... Merger and acquisition activity in the ... of 2019, according to data from HealthCareMandA.com. The total is the lowest reported in ... when 65 deals were announced. , One deal disclosed a price in the fourth ...
(Date:1/23/2020)... Del. (PRWEB) , ... January 23, 2020 , ... ... coaching and risk services for organizations that operate vehicle fleets in North America ... new subscriber-based e-newsletter, will be published monthly with content accessible on the company’s ...
(Date:1/23/2020)... ... , ... The Incentive Research Foundation is pleased to announce ... segments of the incentives, rewards, and recognition industry, the IRF Board of Trustees ... highlighting the power of incentive and motivational programs. The Board recently met to ...
(Date:1/22/2020)... ... January 22, 2020 , ... In Partnership with the ... dental services for low-income, underinsured individuals at its Largo, FL office on March 7th. ... x-rays , fillings , cleanings and extractions . For more ...
Breaking Medicine News(10 mins):
(Date:1/23/2020)... ... 23, 2020 , ... In the largest genetic sequencing study ... with risk for autism. The study also shows significant progress towards teasing apart ... delay, conditions which often overlap. The study results are published online January 23 ...
(Date:1/23/2020)... (PRWEB) , ... January 23, 2020 , ... ... pain have trusted Australian Dream® for effective relief. Now, the company ... relief. , Australian Dream sought to develop a new design that better communicates ...
(Date:1/23/2020)... Mass. (PRWEB) , ... January 23, 2020 , ... ... of evidence-based clinical resource tools, has announced the availability of a new decision ... Treatment Options presents several pharmacotherapeutic options to manage opioid addiction. , Opioid addiction ...
Breaking Medicine Technology:
Cached News: