HOME >> MEDICINE >> NEWS
Bone Marrow With Organ Transplants Reduces Rejection Of Transplanted Organs, Reports University Of Pittsburgh

Results of clinical study presented at Experimental Biology '99 meeting

WASHINGTON, D.C., April 21 -- Organ rejection occurs less often and is less severe in patients who receive infusions of bone marrow from the same donor, researchers from the University of Pittsburgh's Thomas E. Starzl Transplantation Institute report today at Experimental Biology '99. Their findings, which represent six years of study of patients who received the extra boost of donor immune system cells, indicate the procedure is safe and augments the cellular environment that the research team believes is necessary for long-term acceptance of a transplanted organ.

Results of the study--the largest of its kind--are particularly encouraging for the recipients of hearts, lungs and combined kidney and pancreas, reports Abdul Rao, M.D., D.Phil., assistant professor of surgery and pathology and director, section of cellular transplantation. In addition, the outcomes for liver transplant patients suggest that some patients can be weaned from the drugs that control organ rejection. The researchers are selecting these patients for a step-wise weaning protocol, which has not yet been initiated.

Controlling rejection is the key to successful organ transplantation. For the most part, surgeons rely on drugs that suppress the patient's immune response as their main line of defense against an immune system attack. But despite newer and better drugs, organ rejection can still occur, even years after transplantation. Even if the drugs effectively control rejection, they can produce serious medical complications and make the patient more susceptible to cancers and infections, some which can be deadly.

"While the ultimate goal in some of the bone marrow patients is to take them off immunosuppressive drugs, we do not want to interfere with the natural peace-keeping process between the recipient and donor immune systems. In other words, the drugs are necessary, at le
'"/>

Contact: Lisa Rossi
rossiL@msx.upmc.edu
412-624-2607
University of Pittsburgh Medical Center
21-Apr-1999


Page: 1 2 3 4

Related medicine news :

1. Marrow injection gets damaged hearts moving
2. Less Toxic Bone Marrow Transplant Technique May Have More Powerful Anti-Cancer Effect
3. Organ Transplants Helped By Donor Bone Marrow, University Of Pittsburgh Researchers Report At National Transplant Meetings
4. Bone Marrow With Heart And Lung Transplants Reduces Rejection Of Transplanted Organs, Reports University Of Pittsburgh
5. Duke Researchers Identify New Pulmonary Syndrome Associated With Bone Marrow Transplantation For Breast Cancer
6. Organizational traits associated with quality patient care are essential to home care nursing
7. Roche pledges continued support for Organ Transplantation Research Foundation
8. Organ-transplant patients at particluar risk from low MMR vaccine uptake
9. Organ transplant recipients face serious kidney-failure risk, study finds
10. Organically grown foods higher in cancer-fighting chemicals than conventionally grown foods
11. National Conference on Organ Donation and Transplantation

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... ... Talented host, actor Rob Lowe, is introducing a segment ... of "Success Files," which is an award-winning educational program broadcasted on PBS Member ... with passion and integrity. , Sciatica occurs when the sciatic nerve in the ...
(Date:10/12/2017)... ... October 12, 2017 , ... First Healthcare Compliance (FHC), ... will showcase a range of technology and learning solutions at the 68th Annual ... Expo to be held October 14–18, 2017 at the Mandalay Bay Resort in ...
(Date:10/12/2017)... PALM CITY, Fla. (PRWEB) , ... October 12, 2017 , ... ... of cold therapy products, announced today the introduction of an innovative new design of ... the multipurpose pad so you get maximum comfort while controlling your pain while using ...
(Date:10/12/2017)... LOS ANGELES (PRWEB) , ... October 12, 2017 ... ... of Parsa Mohebi Hair Restoration, has recently contributed a medical article to the ... doctors, on cosmetictown.com. Dr. Mohebi’s article spotlights the hair transplant procedure known as ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... one of Michigan’s 2017 Best and Brightest in Wellness® by Best and Brightest. ... awards program on Friday, Oct. 20 from 7:30 a.m. to 2 p.m. at ...
Breaking Medicine News(10 mins):
(Date:9/22/2017)... AVACEN Medical (AVACEN) announced that its CE-Marked ... those with the widespread pain associated with fibromyalgia in ... Essex, England commented, "I had ... no sleep at all, tremendous pain, with every movement ... [the AVACEN 100] enough, how this has and is ...
(Date:9/18/2017)... , Sept. 18, 2017 ... fields of bioinformatics and immune engineering, today ... protective avian influenza A (H7N9) vaccine. ... related to seasonal influenza and presents a ... on prior exposure to be effective. Using ...
(Date:9/12/2017)... 2017  ValGenesis Inc., the global leader in ... to announce the appointment of Dr. Ajaz ... of Directors and Chairman of Advisory Board beginning ... companies to manage their entire validation lifecycle process ... this process. Furthermore, ValGenesis VLMS enables rigorous compliance, ...
Breaking Medicine Technology:
Cached News: