HOME >> MEDICINE >> NEWS
Brain activity, including memory-processing, changes in Tourette syndrome

St. Louis, April 5, 2004 -- Scientists have known for years that abnormal activity involving a brain chemical called dopamine is somehow connected to the movements and vocalizations, or tics, associated with Tourette syndrome. Now neuroscience researchers at Washington University School of Medicine in St. Louis have found brain activity in these patients is abnormal during memory tasks, as well.

The researchers also found that giving Tourette syndrome patients the drug levodopa, which is used to treat abnormal dopamine activity in conditions such as Parkinson's disease, normalized brain activity during the memory tasks.

"We've observed in the living brain a dopamine-sensitive abnormality in people with tics. That's been hypothesized for 40 years, but this is the first time it's been demonstrated," says principal investigator Kevin J. Black, M.D., assistant professor of psychiatry, neurology and radiology and staff physician at Barnes-Jewish Hospital. "We actually have a direct demonstration of abnormal brain activation in people with Tourette syndrome that is corrected when they are given a dopamine-type medicine."

The study is published online and will appear in the May issue of the journal Biological Psychiatry.

Using functional magnetic resonance imaging (fMRI), the researchers compared eight adults with Tourette syndrome to 10 age- and gender-matched individuals without tics. Brain scans were taken while participants performed a memory task that involved remembering and identifying letters on a computer screen. The task measures working memory, a type of short-term memory that involves concentration on several things at once.

"We chose to look at the brain's response to a working memory task because past research has shown that working memory could be affected by dopamine levels in the brain," says first author Tamara Hershey, Ph.D., assistant professor of psychiatry and neurology at the School of Medicine. "We a
'"/>

Contact: Jim Dryden
jdryden@wustl.edu
314-286-0110
Washington University School of Medicine
5-Apr-2004


Page: 1 2 3

Related medicine news :

1. Brain activity prior to treatment flags vulnerability to antidepressant side effects
2. Brain imaging study may hold clues to onset of schizophrenia in people at high risk
3. Brain imaging reveals secrets of love, fear and betrayal
4. Brain imaging studies investigate pain reduction by hypnosis
5. Brain tumor with dismal prognosis in infants can be cured in older children
6. Brain-scanning technologies need standards, according to Stanford researcher
7. Brain activity of men and women during hostile or impulsive acts differs less on nicotine
8. Brain synapse formation linked to proteins, Stanford study finds
9. Brain tumor treatment can vary greatly, according to new JAMA study
10. Brain region identified that controls collecting behavior
11. Brain imaging reveals new language circuits

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/22/2017)... CA (PRWEB) , ... August 22, 2017 , ... ... accessible luxurious collection of unique masks and serums that perfectly fuse the beauty ... care advancements, at the 2017 Indie Beauty Expo on August 23rd & 24th ...
(Date:8/22/2017)... Davis, California (PRWEB) , ... August 22, 2017 ... ... implies that the key to good health is as simple as eating healthy ... to food—whether it be storing fat, making insulin, or breaking apart carbohydrates—depends not ...
(Date:8/22/2017)... , ... August 22, 2017 , ... ... pleased to announce the addition of Zack Tisch as the firm’s new Consulting ... KLAS-ranked healthcare IT consulting firm’s national accounts, from assisting clients with initial vendor ...
(Date:8/22/2017)... ... August 22, 2017 , ... GeBBS Healthcare ... the availability of a new professional fee E/M leveling calculator tool. The new ... the healthcare industry. E/M coding is complex which supports the need for a ...
(Date:8/22/2017)... ... ... Star Glass is new to the Texas market, but is proudly managed by widely recognized ... and models, in Grand Prairie, TX, located in the center of the DFW Metroplex, the ... business for the past 40 years with 32 convenient locations in Texas, Nevada and California ...
Breaking Medicine News(10 mins):
(Date:8/18/2017)... 18, 2017  Nortis today announced the awarding of a $688K National Institutes ... third year of a Small Business Innovation Research (SBIR)?Fast-track grant ... Neurological Disorders and Stroke (NINDS).?  ... Nortis ParVivo Chip used for ... ...
(Date:8/17/2017)... EWING, N.J. , Aug. 17, 2017 Bio-Ess Laboratories, LLC ... to increase antibody titer and present new data on Cell-Ess® ... in Boston, MA August 21-25.  The Bioprocessing ... for today,s bioprocess challenges. ... Boost and Optimizer ...
(Date:8/15/2017)... 15, 2017  Axium Pharmaceuticals Inc., the creator of the drug ... the beginning stages of an IPO. The United ... the average cost of a prescription epilepsy drug being $450.00-$1200.00 for a ... AXIUM PHARMACEUTICALS, INC ... Another staggering figure is the fact that Americans spent $42 ...
Breaking Medicine Technology:
Cached News: