HOME >> MEDICINE >> NEWS
Brain activity prior to treatment flags vulnerability to antidepressant side effects

In a finding that opens new doors to determining susceptibility to antidepressant side effects, researchers at the UCLA Neuropsychiatric Institute report that changes in brain activity prior to treatment with antidepressants can flag patient vulnerability.

Published in the April 2005 edition of the peer-reviewed journal Neuropsychopharmacology, the study is the first to link brain function and medication side effects, and to show a relationship between brain function changes during brief placebo treatment and later side effects during treatment with medication.

The study's unique design compares brain function changes in healthy research subjects with no history of depression while taking an antidepressant vs. placebo, a pill with inactive ingredients. In addition, all participants took only placebo for one week prior to randomization to medication or placebo.

Using "cordance," a quantitative electroencephalography (QEEG) imaging technique developed at UCLA, the research team found changes in brain function in the prefrontal region during the one-week placebo lead-in were related to side effects in subjects who received an antidepressant.

"This finding shows the promise of new ways for assessing susceptibility to antidepressant side effects," said Aimee M. Hunter, lead author and research fellow at the UCLA Neuropsychiatric Institute.

"The ability to identify individuals who are at greatest risk of side effects would greatly improve the success rate of antidepressant treatment," Hunter said. "For example, physicians might select a medication with a lower side-effect profile, start medication at a lower dose or opt for psychotherapy alone when treating patients susceptible to antidepressant side effects."

Antidepressant side effects can be related to medication or to factors such as patient expectations derived from educational materials or consultations with a physician, but determining vulnerability or cause in a clin
'"/>

Contact: Dan Page
dpage@mednet.ucla.edu
310-794-2265
University of California - Los Angeles
30-Mar-2005


Page: 1 2

Related medicine news :

1. Brain imaging study may hold clues to onset of schizophrenia in people at high risk
2. Brain imaging reveals secrets of love, fear and betrayal
3. Brain imaging studies investigate pain reduction by hypnosis
4. Brain tumor with dismal prognosis in infants can be cured in older children
5. Brain-scanning technologies need standards, according to Stanford researcher
6. Brain activity of men and women during hostile or impulsive acts differs less on nicotine
7. Brain synapse formation linked to proteins, Stanford study finds
8. Brain tumor treatment can vary greatly, according to new JAMA study
9. Brain region identified that controls collecting behavior
10. Brain imaging reveals new language circuits
11. Brain can be trained to process sound in alternate way, study shows

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... October 13, 2017 , ... Many families have long-term insurance that covers care ... have a waiver for care if the client has a cognitive impairment diagnosis. ... for care, is often waived, so the benefits from their insurance start immediately,” said ...
(Date:10/13/2017)... ... 2017 , ... Global Healthcare Management’s 4th Annual Kids Fun Run brought out ... free event, sponsored by Global Healthcare Management’s CEO, Jon Letko, is aimed at getting ... children of all ages; it is a non-competitive, non-timed event, which is all about ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... Agile Software Development, has been awarded a contract by the Center for Medicare ... (BPA) aims to accelerate the enterprise use of Agile methodologies in a consistent ...
(Date:10/12/2017)... ... October 12, 2017 , ... First ... compliance program management, will showcase a range of technology and learning solutions at ... (NCAL) Convention and Expo to be held October 14–18, 2017 at the Mandalay ...
(Date:10/12/2017)... ... October 12, 2017 , ... The company ... of today’s consumer and regulatory authorities worldwide. From Children’s to Adults 50+, every ... meet the highest standard. , These products are also: Gluten Free, Non-GMO, ...
Breaking Medicine News(10 mins):
(Date:9/28/2017)... -- Cohen Veterans Bioscience and Early Signal Foundation announce ... home sensors for real-time monitoring of patients with trauma-related ... organization focused on disruptive health solutions for rare disorders ... to record and integrate behavioral, cognitive, physiological and contextual ... ...
(Date:9/27/2017)... , Sept. 27, 2017  DarioHealth Corp. (NASDAQ: DRIO), a leading global ... that its MyDario product is expected to appear on The Dr. Oz ... Dr. Oz Show airs in your area: http://www.doctoroz.com/page/where-watch-dr-oz-show ... The nine-time Emmy award-winning, The Dr. Oz Show kicked ... The segment features ...
(Date:9/25/2017)... 2017  EpiVax, Inc., a leader in the ... today announced the launch of EpiVax Oncology Inc., ... therapeutic cancer vaccines. EpiVax has provided $500,000 in ... enabling technologies to the new precision immunotherapy venture. ... Oncology as Chief Executive Officer. Gad brings over ...
Breaking Medicine Technology:
Cached News: