HOME >> MEDICINE >> NEWS
Brain-imaging study sheds more light on underlying cause of attention-deficit hyperactivity syndrome

Results of a US study in this week's issue of THE LANCET provide details of the underlying physical causes of attention-deficit hyperactivity syndrome, with reductions in size of some brain areas and an increase in grey matter proportions being characteristic of children with the disorder.

Attention-deficit hyperactivity disorder (ADHD) is a serious neuropsychiatric problem in schoolchildren (an estimated 3-6% of US schoolchildren are affected, for example). The disorder is characterised by poor attention span, impulsivity, and high motor activity. Its nature and cause are poorly understood, although previous research has suggested that structural changes in areas of the brain controlling attention are responsible for the disorder.

Elizabeth R Sowell, Assistant Professor of Neurology from the Laboratory of Neuro Imaging at the University of California Los Angeles, USA, and colleagues undertook the first detailed morphological study using high-resolution magnetic resonance imaging (MRI) and sophisticated computational systems to more accurately determine the specific areas of the brain underlying ADHD. Brain assessment of 27 children (11 girls, 16 boys) and adolescents with ADHD was compared with that of 46 control children without ADHD who were matched for age and sex.

Abnormal brain structure was observed in the frontal cortices (on both sides of the brain) of children with ADHD, with reduced regional brain size localised mainly to small areas of the dorsal prefrontal cortices. Children with ADHD also had reduced brain size in anterior temporal areas, also on both sides of the brain. Substantial increases in grey matter were recorded in large portions of the posterior temporal and inferior parietal cortices in children with ADHD.

Elizabeth R Sowell comments: "Our morphometric procedures allow more precise localisation of group differences than do the methods used in previous studies. Our results therefore suggest that the disturban
'"/>

Contact: Joe Santangelo
j.santangelo@elsevier.com
212-633-3810
Lancet
20-Nov-2003


Page: 1 2

Related medicine news :

1. Brain-imaging cap under study for space and Earth use
2. Brain-imaging study offers clues to inhalant abuse
3. First head-to-head study to compare lidoderm patch and Celebrex in treating pain
4. UMaine study looks at infants and chronic nighttime crying
5. Chronic pain treatments more effective when taken together, new study shows
6. UNC study: Most N.C. family practitioners engage in unrecognized community service
7. New study in Nature demonstrates protection against cell death during heart attack
8. UCSF study offers insight into human circadian rhythms
9. International breast cancer prevention study launches in the United States and Canada
10. UW study shows blacks and Latinos are more satisfied with physicians of the same race
11. Physicians may not be accurate in their confidence levels of their diagnoses, says Pitt study

Post Your Comments:
(Date:8/22/2014)... Newport Hospital has again attained the distinguished Magnet ... (ANCC) Magnet Recognition Program. Considered the gold standard ... recognizes nursing excellence and professionalism. It is the ... unanimous decision to redesignate Newport Hospital was based ... standards of nursing practice. , "It is a ...
(Date:8/22/2014)... August 22, 2014 Home Care ... in-home care for seniors, is proud to announce the ... The upcoming webinar will feature Dr. Suzanne Steinbaum, attending ... Hill Hospital in New York City, National Spokesperson for ... The webinar will cover the issues surrounding women and ...
(Date:8/22/2014)... FRIDAY, Aug. 22, 2014 (HealthDay News) -- Counseling may ... a large-scale review finds. Researchers analyzed 66 studies ... of whom were at high risk for drinking problems. ... session, while participants in the rest of the studies ... individual sessions. A counseling technique called motivational interviewing ...
(Date:8/22/2014)... Aug. 22, 2014 (HealthDay News) -- Inner city children have ... finds. Researchers followed 516 inner city children in four ... -- from birth until age 5 and found that at ... eggs or peanuts. Because only the three most common ... actual number of inner city youngsters with food allergies may ...
(Date:8/22/2014)... the previous few years, several breakthrough treatments have ... Patients who may benefit from these treatments can ... in their cancer. For example, patients whose lung ... ALK derive significant benefit from the drug crizotinib, ... are now attempting to replicate this success by ...
Breaking Medicine News(10 mins):Health News:Newport Hospital receives nursing's highest credential for third time with Magnet recognition 2Health News:Home Care Assistance of Centennial to Host Webinar on Heart Health, Featuring Dr. Suzanne Steinbaum 2Health News:Home Care Assistance of Centennial to Host Webinar on Heart Health, Featuring Dr. Suzanne Steinbaum 3Health News:Counseling Does Little to Deter Youth Drinking, Review Finds 2Health News:Food Allergies More Common Among Inner City Kids, Study Finds 2Health News:Online screening for rare lung cancer subtypes opens door to new kind of clinical trial 2Health News:Online screening for rare lung cancer subtypes opens door to new kind of clinical trial 3Health News:Online screening for rare lung cancer subtypes opens door to new kind of clinical trial 4
(Date:8/22/2014)... , Aug. 22, 2014 Research and ... Cell Research Products: Opportunities, Tools & Technologies" report ... supply stem cell research products or you wish to ... and lucrative this market is. The authors know you ... more effectively to scientists, to generate improved revenues and ...
(Date:8/22/2014)... Research and Markets has announced ... Catheter Industry Report 2014" report to their offering. ... Industry Report 2014 is a professional and in-depth study ... industry with a focus on the Chinese situation. ... including definitions, classifications, applications and industry chain structure. The ...
(Date:8/22/2014)... Cali ., Aug. 22, 2014  Research presented ... that a therapy being developed by Hera Therapeutics Inc. combats ... 70 percent of all cervical cancer. When tested ... of HPV-16, HPV-18 and HPV-11 cells, according to Louise ... who presented the findings at the Seattle ...
Breaking Medicine Technology:Global Stem Cell Research Products: Opportunities, Tools & Technologies - 2014 Report 2Global Stem Cell Research Products: Opportunities, Tools & Technologies - 2014 Report 3Global and Chinese Intravenous Catheter Industry Report 2014 2Study shows Hera Therapeutics experimental compound shuts down human papillomavirus that causes most cervical cancer 2
Cached News: