HOME >> MEDICINE >> NEWS
Brain shrinkage in ADHD not caused by medications

A 10-year study by National Institute of Mental Health (NIMH) scientists has found that brains of children and adolescents with Attention Deficit Hyperactivity Disorder (ADHD) are 3-4 percent smaller than those of children who don't have the disorder and that medication treatment is not the cause. Indeed, in this first major study to scan previously never-medicated patients, they found "strikingly smaller" white matter volumes in children who had not taken stimulant drugs. Still, the course of brain development in the ADHD patients paralleled that of normal subjects, suggesting that whatever caused the disorder happened earlier.

Drs. Xavier Castellanos, Judith Rapoport, NIMH Child Psychiatry Branch, and colleagues, report on their magnetic resonance imaging (MRI) study of 152 boys and girls with ADHD in the October 9, 2002 Journal of the American Medical Association.

Affecting 3-5 percent of school-age children, ADHD is characterized by over-activity, distractibility and impulsiveness. The disorder affects two to three times as many boys as girls, with as many as 20 percent of boys taking stimulant medication in some school systems. The new study strengthens the validity of the diagnosis by helping to put to rest criticism that structural brain abnormalities seen in ADHD might be drug-induced.

"There is no evidence that medication harms the brain," said Castellanos, who conducted the study at NIMH before joining New York University. "It's possible that medication may promote brain maturation."

Launched in l991, the study used MRI to scan 89 male and 63 female patients ages 5-18, with ADHD, and 139 age- and gender-matched controls, children and adolescents without ADHD. Most patients were scanned at least twice, and some up to four times over the decade.

As a group, ADHD patients showed 3-4 percent smaller brain volumes, in all regions. The more severe a patient's ADHD symptoms as rated by parents and clinicians th
'"/>

Contact: Jules Asher
NIMHpress@mail.nih.gov
301-443-4536
NIH/National Institute of Mental Health
8-Oct-2002


Page: 1 2 3

Related medicine news :

1. Brain activity prior to treatment flags vulnerability to antidepressant side effects
2. Brain imaging study may hold clues to onset of schizophrenia in people at high risk
3. Brain imaging reveals secrets of love, fear and betrayal
4. Brain imaging studies investigate pain reduction by hypnosis
5. Brain tumor with dismal prognosis in infants can be cured in older children
6. Brain-scanning technologies need standards, according to Stanford researcher
7. Brain activity of men and women during hostile or impulsive acts differs less on nicotine
8. Brain synapse formation linked to proteins, Stanford study finds
9. Brain tumor treatment can vary greatly, according to new JAMA study
10. Brain region identified that controls collecting behavior
11. Brain imaging reveals new language circuits

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Brain shrinkage ADHD not caused medications

(Date:5/27/2015)... CT (PRWEB) May 27, 2015 Dr. ... Institute based in Stamford, CT has been selected as ... the first physicians nationwide (and the only physician in ... injectable which allows for the removal of submental fat ... to no recovery time, no surgery and minimal risks. ...
(Date:5/27/2015)... Black Book Rankings, well known internationally ... multiple services and software industries, conducted a sweeping ... Electronic Health and Medical Record software systems for ... on implemented EHR users, Black Book reveals industry ... highest scores in client experience among small and ...
(Date:5/27/2015)... May 27, 2015 The Case ... a partnership to provide CMSA's Career and Knowledge ... collaboration seeks to strengthen the case/care management workforce ... CKP program. The mutually beneficial agreement provides Medix, ... skills of talent in the healthcare, scientific and ...
(Date:5/27/2015)... Difass USA, a modern supplement brand committed ... first three flagship products, Dormiva™, Relaxiva™ and Reminiva™. All ... http://www.difassusa.com . , A restful night’s sleep is ... people struggle with getting the full amount of sleep ... designed to help you fall asleep and stay asleep, ...
(Date:5/27/2015)... IL (PRWEB) May 27, 2015 On ... North-based advertising agency, will partner with LifeSource to host ... event will take place in a LifeSource donor coach ... a.m. to 4:00 p.m. , Demand for whole blood ... in Illinois, during the summer months. LifeSource requires approximately ...
Breaking Medicine News(10 mins):Health News:Connecticut Skin Institute First in Connecticut to Offer New Surgery-Free “Double Chin” Fat Reduction Treatment 2Health News:Connecticut Skin Institute First in Connecticut to Offer New Surgery-Free “Double Chin” Fat Reduction Treatment 3Health News:Cloud-Based Electronic Health Record firms sweep top physician satisfaction rankings for Small and Solo Practices, reveals 2015 Black Book survey 2Health News:Cloud-Based Electronic Health Record firms sweep top physician satisfaction rankings for Small and Solo Practices, reveals 2015 Black Book survey 3Health News:Cloud-Based Electronic Health Record firms sweep top physician satisfaction rankings for Small and Solo Practices, reveals 2015 Black Book survey 4Health News:Case Management Society of America Partners with Medix to Offer Career and Knowledge Pathways 2Health News:Case Management Society of America Partners with Medix to Offer Career and Knowledge Pathways 3Health News:Supplement Brand Difass USA Launches in the U.S. with Three Flagship Products Designed to Bring Balance Back to Your Life 2Health News:Donate Your Break and Save Lives at the River North Blood Drive 2
(Date:5/27/2015)... -- Research and Markets( http://www.researchandmarkets.com/research/d85hx9/global_rapid ) has announced the ... Market - Applications and Technologies" report to their ... Kits, estimated at US$19.4 billion in 2014, forecast at ... a CAGR of 5.7% between 2014 and 2020 to ... The global market for Rapid Medical Diagnostic Kits (MDKs) ...
(Date:5/27/2015)... , May 27, 2015  With Freudenberg ... a unique service: machined seals from the ... The seals, that have the same material ... original Freudenberg-NOK series products, can be made-to-order ... cost-effective small production runs. The agenda is ...
(Date:5/27/2015)... , LONDON and ... - http://www.abmrg.com/Indonesia-Respiratory-Devices-and-Respiratory-Diagnostics-Market-through-2020---Detailed-analysis-of-Hospital-and-Retail-market.html - Over ... - Around 400,000 Indonesians die annually due to ... - Three-fourths of 6.5 million vehicles in ... test Indonesia is ...
Breaking Medicine Technology:Global Rapid Medical Diagnostic Kits Market - 2015-2020 Applications and Technologies Analysis of the $27 Billion Industry 2Global Rapid Medical Diagnostic Kits Market - 2015-2020 Applications and Technologies Analysis of the $27 Billion Industry 3Global Rapid Medical Diagnostic Kits Market - 2015-2020 Applications and Technologies Analysis of the $27 Billion Industry 4Xpress Service from Freudenberg-NOK Quickly Delivers Made-to-Order Sealing Solutions to Customers 2Indonesia Respiratory Devices Market is Expected to Grow at a CAGR of 9% - Boosting Growth for Respiratory Disposables 2Indonesia Respiratory Devices Market is Expected to Grow at a CAGR of 9% - Boosting Growth for Respiratory Disposables 3Indonesia Respiratory Devices Market is Expected to Grow at a CAGR of 9% - Boosting Growth for Respiratory Disposables 4
Cached News: