HOME >> MEDICINE >> NEWS
Breakthrough? Study Finds Dopamine Cannot Be Source Of Pleasure In Brain

CHAPEL HILL - Dopamine, a chemical messenger believed for more than two decades to be the end point of the brain's pleasure system, appears not to be that molecular reward after all, a new study shows.

The University of North Carolina at Chapel Hill study suggests instead that dopamine plays an early central role in pleasure, but another chemical -- possibly serotonin -- actually rings the chimes for humans and animals alike.

Researchers say their discovery should become important in the search for solutions to substance abuse and addiction problems, researchers say.

A report on the findings appears in the March 4 issue of the journal Nature. Authors are Drs. Paul A. Garris, a postdoctoral fellow at UNC-CH now at Illinois State University, and R. Mark Wightman, William Rand Kenan Jr. professor of chemistry at UNC-CH. Others are Michaux Kilpatrick, an M.D.-Ph.D. student in Wightman's laboratory; Dr. Melissa A. Bunin, a former graduate student doing postdoctoral work in Australia; graduate student Daren Michael, and Dr. David Walker, now a Duke University postdoctoral scientist.

In what the journal dubbed "something of a technical tour de force," the studies first involved developing a carbon fiber electrode one tenth the thickness of a human hair and coating it with glass.

"When implanted in rat brains, this micro-sensor allows us for the first time to measure very small amounts of chemical messengers, or neurotransmitters, on a split-second time scale," Wightman said. "That was not possible before."

Using their device coupled with electronic equipment, Wightman and his students can record what happens inside the brain as neurotransmitters such as dopamine interact with one another in real time. They incorporated into the work experiments pioneered by Canadian researchers in which rats quickly learn that by pressing a lever, they can receive a tiny but pleasurable shock to their b
'"/>

Contact: David Williamson
David_Williamson@unc.edu
919-962-8596
University of North Carolina at Chapel Hill
3-Mar-1999


Page: 1 2

Related medicine news :

1. Study of energy and health in Africa focuses spotlight on charcoal and forest management
2. Study shows promise in identifying kidney failure
3. Study shows patch therapy may be as effective as oral medications
4. Study shows soy is well accepted in school lunches
5. Study finds that coordinating care of chronically ill patients does not increase liability
6. Study provides new estimates of the causes of child mortality worldwide
7. Study finds factors linked to substance use disorder relapse among health care professionals
8. Study finds majority of women willing to accept cervical cancer vaccine for self and children
9. Study shows use of budesonide reduced the risk of asthma related events by 40% in children
10. Study shows risk of cardiac death after radiation for breast cancer has dramatically decreased
11. Study shows acrylamide in baked and fried food does not increase risk of breast cancer in women

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:11/16/2018)... , ... November 16, 2018 , ... ... companies are thinking about delivery systems that can improve compliance early in the ... total market for biopharmaceutical drug delivery devices is estimated at $7.8 billion, boosted ...
(Date:11/16/2018)... ... November 16, 2018 , ... The Colorado Rural Health Center (CRHC) is proud ... in our community during National Rural Health Day 2018. National Rural Health Day falls ... serving the health needs of over 60 million people across the nation. , ...
(Date:11/16/2018)... BEACH, Fla. (PRWEB) , ... November 16, 2018 , ... ... 401-building inside the TED Center complex located in the heart of Delray ... with the south county chapter of the Florida Woman Owned Business Center . ...
(Date:11/16/2018)... ... ... Nutrex Research has launched a new series of weight loss supplements ... TopiSorbTM Technology, this gel quickly absorbs and targets subcutaneous and visceral fat via the ... , Maximizing fat loss by applying topical treatments directly to areas of concern can ...
(Date:11/16/2018)... ... November 16, 2018 , ... Hangover Heaven®, a ... medications and antioxidants, has changed its name to Hangover Heaven IV Hydration® in ... focused on IV therapy and IV hydration through our hangover cures products, we ...
Breaking Medicine News(10 mins):
(Date:11/20/2018)... FREEHOLD, N.J. (PRWEB) , ... November 20, 2018 , ... ... family and friends. Unfortunately there are many people who are cold and don't ... along with many members of the Association of NJ Chiropractors (ANJC) hold the annual ...
(Date:11/18/2018)... ... November 18, 2018 , ... Millennials are creating their own ... of their baby boomer parents have turned to fake trees as they have ... natural, and meaningful. Their purchasing decisions and preferences are driving trends from artisan goods, ...
(Date:11/17/2018)... ... , ... Getting ready for the holidays but dread blowing your diet? Whether ... you certainly can enjoy the bounty of the season in a healthy way. ... and how much," says Ronald Stern, M.D., author of Meals, Movement and Meditation ...
Breaking Medicine Technology:
Cached News: