HOME >> MEDICINE >> NEWS
Breast conserving therapy safe for hereditary breast cancer

Women with hereditary breast cancer treated with breast conserving therapy appear to have no increased risk for recurrence in the treated breast, according to results from a prospective study published in the January 1, 2005 issue of CANCER (http://www.interscience.wiley.com/cancer-newsroom), a peer-reviewed journal of the American Cancer Society. However, the risk of breast cancer in the opposite breast is significantly increased.

Breast conserving therapy (BCT), consisting of lumpectomy and radiation, has been demonstrated to be a safe, effective treatment for non-hereditary or sporadic forms of early breast cancer. However, for hereditary breast cancers i.e., mutations in BRCA1 and BRCA2 genes the use of BCT is controversial due to conflicting data about increased risk of recurrence in the treated breast and development of new tumors in the untreated breast. This leaves women with BRCA mutations at a disadvantage when choosing between BCT and bilateral mastectomy.

Mark Robson, M.D. and his colleagues from Memorial Sloan-Kettering Cancer Center in New York City followed 87 women diagnosed with breast cancer and BRCA mutations who were treated with BCT to evaluate their long-term cancer risks.

The investigators found no increase in the risk of cancer recurrence in the treated breast, compared to young women without mutations. Ten years after their initial diagnosis, 13.6 percent of the women with a genetic mutation had experienced a recurrence similar to previously published recurrence rates for women with non-hereditary breast cancers treated with BCT. However, the researchers note that more than half the women suffered a cancer-related event (recurrence or second primary cancer) within ten years of their initial diagnosis, including 37.6 percent who experienced a new cancer in the untreated breast. No clinical risk factors were linked to an increased risk of cancer. '"/>

Contact: David Greenberg
dgreenbe@wiley.com
201-748-6484
John Wiley & Sons, Inc.
22-Nov-2004


Page: 1 2

Related medicine news :

1. Hausman to give keynote address at Breastfeeding, Motherhood and Feminism symposium
2. Breast implant Website launched by leading plastic surgery societies
3. Breast cancer treatment reduces risk of heart disease
4. Breast reconstruction with implants after mastectomy doesnt hurt survival chances
5. Breast cancer may be uniquely sensitive to inhibitors of PI3K pathway
6. Breast MRI moderately useful for detecting breast cancer, but does not eliminate need for biopsy
7. Breast cancer risk, prognosis and weight gain reduced with physical activity
8. Breast cancer in Asian Americans is rising faster than in any other ethnic group
9. Long Island Breast Cancer Study data: Aspirin helps protect some women against breast cancer
10. Breast cancer in men increasing
11. Breast cancers show surprising characteristics on MRI

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/6/2019)... OMAHA, Neb. (PRWEB) , ... December 06, 2019 ... ... staffing and recruiting, has been recognized for excellence in employee learning. The Omaha-based ... , which ranks organizations with the most successful employer-sponsored training and development programs ...
(Date:12/6/2019)... ... December 06, 2019 , ... ... six students in Salt Lake Community College’s (SLCC) Emergency Medical Technician ... and Chelise Schaefer—were awarded the AT&T Public Safety Hero Scholarship to support their ...
(Date:12/6/2019)... ... December 06, 2019 , ... COMPLIANCY GROUP ... for the Wyoming Medical Society. Compliancy Group is dedicated to educating and assisting ... obligation to adhere to the standards set forth by the Health Insurance Portability ...
(Date:12/6/2019)... ... , ... Dr. Scott Howell, a 2019 graduate of Trident University International’s (Trident) ... of coconut oil in the 7 November 2019 edition of Progress in Cardiovascular ... Structured Literature Review,” led by Dr. Hector O. Santos, examines the effect of coconut ...
(Date:12/5/2019)... ... 2019 , ... HealthCareMandA.com is hosting an interesting and important ... December 12, 2019, at 1:00 PM ET. , Private equity firms and managed ... scrambling to assemble regional platforms with enough scale and talent to attract their ...
Breaking Medicine News(10 mins):
(Date:12/6/2019)... ... December 06, 2019 , ... Nobilis ... psychiatric and neurodegenerative disorders, announced today that the U.S. Food and Drug Administration ... the Company to initiate its Phase 2b trial for the treatment of patients ...
(Date:12/6/2019)... ... 2019 , ... Food and nutrition industry leaders recently met ... working toward sustainable nutrition security nationwide, increasing accessibility to nutritious foods for a ... and sustainable food system,” said Carol May, CEO of Wisdom Natural Brands®, maker ...
(Date:12/6/2019)... ... December 06, 2019 , ... Plant ... Fruit Garden Supply LLC (a division of Horticultural Holdings LLC) to recommend Plant ... growers. , FFGS is a team of disciplined and energetic plant lovers ...
Breaking Medicine Technology:
Cached News: