HOME >> MEDICINE >> NEWS
Breast conserving therapy safe for hereditary breast cancer

Women with hereditary breast cancer treated with breast conserving therapy appear to have no increased risk for recurrence in the treated breast, according to results from a prospective study published in the January 1, 2005 issue of CANCER (http://www.interscience.wiley.com/cancer-newsroom), a peer-reviewed journal of the American Cancer Society. However, the risk of breast cancer in the opposite breast is significantly increased.

Breast conserving therapy (BCT), consisting of lumpectomy and radiation, has been demonstrated to be a safe, effective treatment for non-hereditary or sporadic forms of early breast cancer. However, for hereditary breast cancers i.e., mutations in BRCA1 and BRCA2 genes the use of BCT is controversial due to conflicting data about increased risk of recurrence in the treated breast and development of new tumors in the untreated breast. This leaves women with BRCA mutations at a disadvantage when choosing between BCT and bilateral mastectomy.

Mark Robson, M.D. and his colleagues from Memorial Sloan-Kettering Cancer Center in New York City followed 87 women diagnosed with breast cancer and BRCA mutations who were treated with BCT to evaluate their long-term cancer risks.

The investigators found no increase in the risk of cancer recurrence in the treated breast, compared to young women without mutations. Ten years after their initial diagnosis, 13.6 percent of the women with a genetic mutation had experienced a recurrence similar to previously published recurrence rates for women with non-hereditary breast cancers treated with BCT. However, the researchers note that more than half the women suffered a cancer-related event (recurrence or second primary cancer) within ten years of their initial diagnosis, including 37.6 percent who experienced a new cancer in the untreated breast. No clinical risk factors were linked to an increased risk of cancer. '"/>

Contact: David Greenberg
dgreenbe@wiley.com
201-748-6484
John Wiley & Sons, Inc.
22-Nov-2004


Page: 1 2

Related medicine news :

1. Hausman to give keynote address at Breastfeeding, Motherhood and Feminism symposium
2. Breast implant Website launched by leading plastic surgery societies
3. Breast cancer treatment reduces risk of heart disease
4. Breast reconstruction with implants after mastectomy doesnt hurt survival chances
5. Breast cancer may be uniquely sensitive to inhibitors of PI3K pathway
6. Breast MRI moderately useful for detecting breast cancer, but does not eliminate need for biopsy
7. Breast cancer risk, prognosis and weight gain reduced with physical activity
8. Breast cancer in Asian Americans is rising faster than in any other ethnic group
9. Long Island Breast Cancer Study data: Aspirin helps protect some women against breast cancer
10. Breast cancer in men increasing
11. Breast cancers show surprising characteristics on MRI

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/26/2019)... ... March 26, 2019 , ... A premier professional liability ... The Midwest Podiatry Conference in 2019 in Chicago, Illinois at the Hyatt Regency. ... medical associations. The state associations of Illinois, Indiana, Iowa, Michigan, Minnesota, Missouri and ...
(Date:3/25/2019)... ... March 25, 2019 , ... Over 90 hospital representatives from ... March 13 - 15, 2019 for the 3rd Annual Iowa Rural Hospital Conference, “The ... of Public Health through the SHIP and Flex Grant Programs. , Attendees were able ...
(Date:3/25/2019)... ... March 25, 2019 , ... As part of its rapid ... of America is adding a new specialist and pain clinic in South Florida. , ... pain management at a new location: 9970 Central Park Blvd., N, Suite 401, Boca ...
(Date:3/24/2019)... ... 24, 2019 , ... Extracting wisdom teeth, those pesky molars that cause pain and swollen jaws, ... wisdom teeth if they wind up being pulled?” Nipomo dentist, Dr. Perry Patel ... Wisdom teeth, or the third molars, begin to appear between the ages of 17 and ...
(Date:3/23/2019)... , ... March 22, 2019 , ... ... Buckingham, M.D. is pleased to introduce the SkinTyte™ laser treatment at Buckingham Center ... reconstructive surgeon who recognizes the importance of a beautiful face. Buckingham Center clients ...
Breaking Medicine News(10 mins):
(Date:3/26/2019)... ... March 26, 2019 , ... Murrieta Genomics, the genomic ... site management organization, to offer genomic sequencing services to trial sponsors and participants ... enable utilization of genomic sequencing data along with clinical trial information to better ...
(Date:3/26/2019)... PEKIN, Ill. (PRWEB) , ... March 26, 2019 ... ... (iaedp™) announces a First Call for Proposals for its 2020 annual Symposium slated ... , The iaedp™ Foundation is pursuing abstracts on inventive treatment modalities ...
(Date:3/26/2019)... ... March 26, 2019 , ... Viscira, ... sciences industry, is pleased to announce plans for its third annual Digital Innovation ... keep life sciences companies on the cutting edge of all things digital by ...
Breaking Medicine Technology:
Cached News: