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Brookhaven Lab and BioSET develop a synthetic peptide that enhances the effect of BMP-2

al benefit."

The growth factor analogs developed in the Brookhaven/BioSET collaboration are synthetic peptides that are chemically more stable and easier to produce than natural growth factors or growth factors derived by recombinant protein techniques. BioSET has an exclusive license to develop and market these bioactive analogs.

Thomas Rouech, BioSET's president, said, "We are fortunate to enjoy a fruitful collaboration. This class of peptide and others under development supports the concept of design-targeted synthetic peptides for specific tissue regeneration applications. The Brookhaven/BioSET collaboration continues to yield very promising results aimed at replicating human growth factors, and we look forward to further validating the potential of these peptides to enhance the body's healing capacity, especially when combined with orthopedic implants."

He added, "We believe the future of orthopedics will continue evolving towards combination products, such as devices that have been biologically enhanced. For example, approved growth factor-type combination device products are currently valued at over $1.6 billion. Our ability to bring new bioactive peptides into the mix of new product development positions us at the leading edge of an important evolution in orthopedic medicine."


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Contact: Diane Greenberg
greenb@bnl.gov
631-344-2347
DOE/Brookhaven National Laboratory
9-Nov-2004


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