COX-2 inhibitors associated with blood pressure...( coxib they stated. While CO...)

COX-2 inhibitors associated with blood pressure elevation

coxib," they stated.

While COX-2 inhibitors have been considered to be a welcome therapeutic option for arthritis, the authors concluded, "their potential (and differential) effect on blood pressure elevation requires caution in their use and warrants further investigation. Clinicians need to weigh the risks of improved gastrointestinal safety versus potential hazards of developing elevated blood pressure when considering the use of these agents, especially in the elderly population."

(Arch Intern Med. 2005; 165. Available post-embargo at www.archinternmed.com.)

Editor's Note: Dr. Liew has been a consultant to Pfizer regarding cyclooxygenase 2 inhibitors, and Prof. Krum has been a consultant to Pfizer, Merck, and Novartis regarding cyclooxygenase 2 inhibitors. Mr. Haas currently receives assistance via a National Health and Medical Research Council Public Health Postgraduate Research Scholarship. Dr. Liew currently receives assistance via a Royal Australasian College of Physicians Postdoctoral Fellowship.

'"/>

Contact: Henry Krum, M.B.B.S, Ph.D.
Henry.Krum@med.monash.edu.au
JAMA and Archives Journals
14-Feb-2005

Page: 1 2
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