HOME >> MEDICINE >> NEWS
Canadian researchers to develop 'smart drug' to repair psychiatric disorders

"Smart" drugs capable of targeting specific brain cells to control psychiatric disorders such as autism and schizophrenia may be ready for early clinical trials within three years, with the launch of a $1.5 million project to take place at the Brain Research Centre (BRC), a partnership of the University of British Columbia and Vancouver Coastal Health Research Institute (VCHRI).

The new drugs would be the first significant change in decades to medications used to treat psychiatric disorders, says neuroscientist and team leader Yu Tian Wang, a UBC professor of Medicine and BRC member.

"We're designing a whole new generation of medications that will work only on brain cells in areas that need to be repaired," says Wang. "This new type of drug will correct abnormal brain functions in a targeted way, so patients don't experience the side effects found in existing medications that affect the whole brain."

One of only three investigations funded in NeuroScience Canada's new Brain Repair Program, the project brings together five researchers from across Canada, including three investigators from the BRC at UBC Hospital.

Healthy brain functioning relies on a balance between the chemical messengers that stimulate brain cell activity (excitatory neurotransmitters) and those that diminish activity (inhibitory neurotransmitters.)

When balance is disrupted, the flow of information among brain cells in certain areas becomes confused. The result is impairments in perception, thought and behaviour seen in patients with brain disorders ranging from autism to major psychoses including schizophrenia and depression.

Using sophisticated equipment to view, study and manipulate brain messaging at the cellular level, the team will test their design of a type of drug that can fine-tune communication between brain cells and bring excitatory and inhibitory activity into a healthy balance.

Existing anti-psychotic drugs adjust commun
'"/>

Contact: Hilary Thomson
hilary.thomson@ubc.ca
+1-604-822-2644
University of British Columbia
29-Nov-2004


Page: 1 2

Related medicine news :

1. U of T researchers describe Joe Canadian tongue
2. Canadian neurologist wins highest award as American Stroke Association honors five
3. Canadian researchers important discovery in HIV research
4. Impact of 2002 Canadian forest fires felt 700 miles away in Baltimore, Maryland
5. McMaster named Canadian Research University of the Year
6. Safety of Canadian hospitals
7. Patient safety study provides first national estimate of adverse events in Canadian hospitals
8. Canadian doctors dont know costs of prescribed treatments
9. New Canadian study demonstrates clear survival benefit of treatment in trials and at large centres
10. Canadian discovery promises treatment for HIV dementia
11. Most Canadian hospitals below recommended standards

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/2/2020)... ... April 02, 2020 , ... Representatives fighting ... are encouraging their parents, grandparents, and guardians, to file a proof of claim ... in funds will be made available by Purdue as part of its bankruptcy ...
(Date:4/1/2020)... ... April 01, 2020 , ... Velocidy Bio ’s ... revolutionary NEXTGENPCR that decreases the testing time for SARS-CoV-2 to eight minutes, ... unit the size of a shoebox could perform a hundred and eighty (180) amplification ...
(Date:3/28/2020)... (PRWEB) , ... March 27, 2020 , ... ... division of the Suntuity Group of companies, is mobilizing their drone equipment and ... coronavirus. , By leveraging their DJI Enterprise level Matrice and Agras drones, Suntuity ...
(Date:3/28/2020)... CINCINNATI (PRWEB) , ... March 28, 2020 , ... ... revenue cycle management services, integrated practice management, and patient engagement solutions has expanded ... coronavirus outbreak. , In this time of crisis, telemedicine has a big ...
(Date:3/27/2020)... ... March 27, 2020 , ... During a time of global distress and concern about the impact ... the UNITE HERE Education and Support Fund in an effort to assist hospitality ... HERE represents 300,000 working people in the food service , hotel ...
Breaking Medicine News(10 mins):
(Date:3/28/2020)... ... March 27, 2020 , ... Based on his exceptional work ... as its permanent CIO. In this executive leadership team role, Gallant establishes and ... a smooth shopping experience for customers and digital tools that help independent distributors ...
(Date:3/27/2020)... ... ... Shady Grove Fertility (SGF) —home to more than 85,000 babies born—now offers new ... consults , thereby minimizing interruptions in access to fertility care during this pandemic and ... been to improve access to care. We’re pleased to be able to offer patients ...
(Date:3/20/2020)... ... March 20, 2020 , ... ... Group of companies with its US headquarters in New Jersey, recently launched a ... to organizations affected and present in the local communities across New Jersey, Maryland ...
Breaking Medicine Technology:
Cached News: