HOME >> MEDICINE >> NEWS
Cancer researchers seek to predict tumor growth

CLEVELAND--University Hospitals of Cleveland and the Case Western Reserve University schools of medicine and engineering have launched a revolutionary investigation in cancer research as part of a National Cancer Institute (NCI) effort that challenges engineers and oncologists with the development of a systems biology approach to gain understanding and to unlock issues of the most complex cancer biology problems.

"Our objective is to develop a fully integrated team of technology systems scientists and cancer biologists that will target an area of increasing significance called 'mismatch repair defective malignancies," says Timothy J. Kinsella, M.D., the study's principal investigator in Cleveland, Professor and Vincent K. Smith Chair of Radiation Oncology at the Case School of Medicine and University Hospitals of Cleveland. "These malignant cells cause various cancers, so we are investigating two basic approaches for destroying these MMR defective cells."

This UHC/Case study, entitled "Complex Systems and Control of Mismatch Repair Deficient Cells," is part of a new nine-site, $14.9 million NCI project called the Integrative Cancer Biology Program (ICBP). Each site will focus on different targets with one overarching mission: to gain valuable information about the progression of cancer through a systems-wide approach. A multi-disciplinary effort among all fields of cancer research will incorporate genomics, proteomics, and molecular imaging using system theoretic techniques to develop new models that can be used in-silico, that is, in or by means of computer simulation to better understand and predict the dynamics of the cancer process.

MMR defective cells cause hereditary nonpolyposis colon cancer (HNPCC), an inherited disorder, also called Lynch syndrome, that often leads to colon cancer and other types of cancer, most often in people in the 20 to 40-year age group. The disorder affects about 160,000 people in the United States, most of
'"/>

Contact: George Stamatis
George.Stamatis@case.edu
216-368-3635
Case Western Reserve University
8-Nov-2004


Page: 1 2 3

Related medicine news :

1. Cancer in patients with hepatitis C
2. Olson family donates $1 million to Arizona Cancer Center
3. Cancer vaccines: A two-pronged attack?
4. Mayo Clinic Cancer Center receives SPORE grant for brain cancer research from NCI
5. ESMO and Imedex announce partnership for the World Congress on Gastrointestinal Cancer
6. UT Southwestern Moncrief Cancer Center is first in Texas to treat patients with TomoTherapy
7. UGA professor receives $3 million grant from National Cancer Institute for breast cancer research
8. Cancer patients in Europe unite with doctors
9. Fox Chase Cancer Center researchers identify novel target for detecting ovarian cancer in blood
10. Cancer burden seen even many years after diagnosis
11. Cancer cell detection technology wins Kaye Award for Hebrew University researchers

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/31/2020)... ... August 31, 2020 , ... ... directly with persons with autism and other developmental disabilities, as well as supporting ... parent education, adolescents with autism, school consultation, and staff development. She joined the ...
(Date:8/28/2020)... ... August 28, 2020 , ... ... CEO Craig Mandeville was named an Entrepreneur Of The Year® 2020 Florida Award ... entrepreneurial business leaders whose ambitions deliver innovation, growth and prosperity as they build ...
(Date:8/28/2020)... ... August 28, 2020 , ... With ... set out to continue helping the specialty-diet community connect with great, gluten-free brands. ... get coupons, enter giveaways, chat with brands & watch over 50 educational classes... ...
(Date:8/28/2020)... ... 28, 2020 , ... A July 27 article ... at an increased risk of developing severe COVID-19 symptoms. The article does not ... the same organ systems that the coronavirus attacks are already suffering from the ...
(Date:8/27/2020)... ... August 27, 2020 , ... ... with Evolution Labs to provide their students with Suite360:Mental Health and Prevention, a ... Health, Substance Abuse and Child Trafficking Prevention. , Florida schools and districts must ...
Breaking Medicine News(10 mins):
(Date:8/26/2020)... ... 26, 2020 , ... ScripHessco has announced the release of ... down ways that chiropractors can help heal sports injuries and get athletes on ... an unusual amount of pressure and stress on their bodies, so checkups to ...
(Date:8/26/2020)... ... August 26, 2020 , ... Unscrupulous sellers ... kill Coronavirus. While air purification technologies, including GreenTech Environmental’s proprietary methods, have been ... no air purification system has published results of singular and scientific testing against ...
(Date:8/26/2020)... (PRWEB) , ... August 26, 2020 , ... ... RN, CHPN, CHPCA, LNC has added CHC and CPCO to her name. , ... Certification in Healthcare Compliance (CHC) and the Certified Professional Compliance Officer (CPCO.) , ...
Breaking Medicine Technology:
Cached News: