HOME >> MEDICINE >> NEWS
Cancer researchers seek to predict tumor growth

CLEVELAND--University Hospitals of Cleveland and the Case Western Reserve University schools of medicine and engineering have launched a revolutionary investigation in cancer research as part of a National Cancer Institute (NCI) effort that challenges engineers and oncologists with the development of a systems biology approach to gain understanding and to unlock issues of the most complex cancer biology problems.

"Our objective is to develop a fully integrated team of technology systems scientists and cancer biologists that will target an area of increasing significance called 'mismatch repair defective malignancies," says Timothy J. Kinsella, M.D., the study's principal investigator in Cleveland, Professor and Vincent K. Smith Chair of Radiation Oncology at the Case School of Medicine and University Hospitals of Cleveland. "These malignant cells cause various cancers, so we are investigating two basic approaches for destroying these MMR defective cells."

This UHC/Case study, entitled "Complex Systems and Control of Mismatch Repair Deficient Cells," is part of a new nine-site, $14.9 million NCI project called the Integrative Cancer Biology Program (ICBP). Each site will focus on different targets with one overarching mission: to gain valuable information about the progression of cancer through a systems-wide approach. A multi-disciplinary effort among all fields of cancer research will incorporate genomics, proteomics, and molecular imaging using system theoretic techniques to develop new models that can be used in-silico, that is, in or by means of computer simulation to better understand and predict the dynamics of the cancer process.

MMR defective cells cause hereditary nonpolyposis colon cancer (HNPCC), an inherited disorder, also called Lynch syndrome, that often leads to colon cancer and other types of cancer, most often in people in the 20 to 40-year age group. The disorder affects about 160,000 people in the United States, most of
'"/>

Contact: George Stamatis
George.Stamatis@case.edu
216-368-3635
Case Western Reserve University
8-Nov-2004


Page: 1 2 3

Related medicine news :

1. Cancer in patients with hepatitis C
2. Olson family donates $1 million to Arizona Cancer Center
3. Cancer vaccines: A two-pronged attack?
4. Mayo Clinic Cancer Center receives SPORE grant for brain cancer research from NCI
5. ESMO and Imedex announce partnership for the World Congress on Gastrointestinal Cancer
6. UT Southwestern Moncrief Cancer Center is first in Texas to treat patients with TomoTherapy
7. UGA professor receives $3 million grant from National Cancer Institute for breast cancer research
8. Cancer patients in Europe unite with doctors
9. Fox Chase Cancer Center researchers identify novel target for detecting ovarian cancer in blood
10. Cancer burden seen even many years after diagnosis
11. Cancer cell detection technology wins Kaye Award for Hebrew University researchers

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/14/2019)... ... 14, 2019 , ... For two years, the only hospital in the Middle ... the parking lot would make you think of the temporary buildings you would see ... devastated the old building and the hospital carried on, first in tents and then ...
(Date:12/9/2019)... , ... December 09, 2019 , ... WEDI , ... in health care information exchange and a trusted advisor to the U.S. Department of ... to its Board of Directors, election of Officers* as well as the re-election of ...
(Date:12/9/2019)... ... ... OCLI, a Spectrum Vision Partners (SVP) managed practice, has announced the addition ... practice with experience spanning decades. As part of OCLI, Drs. Cary Silverman, Nicholas Xanthos ... 46 Eagle Rock Ave, East Hanover, NJ 07936. , Over the past ...
(Date:12/8/2019)... ... December 07, 2019 , ... Intelligent.com, a trusted ... 55 Best Master of Science in Nursing (MSN) Degree Programs for 2020. The ... universities in the nation. Each program is evaluated based on curriculum quality, graduation ...
(Date:12/6/2019)... (PRWEB) , ... December 06, 2019 , ... ... recruiting, has been recognized for excellence in employee learning. The Omaha-based company has ... ranks organizations with the most successful employer-sponsored training and development programs worldwide. Rankings ...
Breaking Medicine News(10 mins):
(Date:12/6/2019)... , ... December 06, 2019 , ... ... development of treatments for psychiatric and neurodegenerative disorders, announced today that the U.S. ... for NBTX-001 Inhaler, allowing the Company to initiate its Phase 2b trial for ...
(Date:12/6/2019)... ... December 06, 2019 , ... Food and nutrition industry ... and ideas about working toward sustainable nutrition security nationwide, increasing accessibility to nutritious ... develop a healthy and sustainable food system,” said Carol May, CEO of Wisdom ...
(Date:12/6/2019)... , ... December 06, 2019 , ... ... agreement with Forbidden Fruit Garden Supply LLC (a division of Horticultural Holdings LLC) ... clientele of professional growers. , FFGS is a team of disciplined and ...
Breaking Medicine Technology:
Cached News: