CellCept's cardioprotective profile reinforced

Data presented today at the International Society for Heart and Lung Transplantation (ISHLT) annual meeting strengthens the body of evidence that CellCept (mycophenolate mofetil, MMF) has unique benefits for heart transplant patients as the only immunosuppressant that offers:

  • superior survival benefits
  • reduced coronary artery disease
  • the least toxic side effect profile

    The new set of data, compiled by means of state of the art technology, has shown that heart transplant patients treated with CellCept have significantly less coronary artery disease than those treated with azathioprine (AZA) in the first year after heart transplantation (0.005). This finding could further explain the superior survival benefits of CellCept.

    For heart transplant patients, cardiovascular disease is the predominant cause of post-transplant death.3 The body's own immune response to the transplanted organ, and the cocktail of drugs taken by the patient cause an increase in coronary artery disease and other risk factors such as hypertension, diabetes and hyperlipidaemia. However, unlike other immunosuppressants, CellCept is NOT associated with these risk factors.

    "These results add to the body of evidence demonstrating the superior efficacy, low-toxicity and cardioprotective profile of CellCept. They show CellCept to offer real long-term benefits to patients, both in terms of overall patient survival and health of the graft," comments William M. Burns, Head of Roche's Pharmaceuticals Division. "CellCept has boosted prescriber confidence and is the ideal cornerstone immunosuppressive agent for 'heart healthy' treatment regimens."

    About the study

    A total of 650 heart transplant patients from 28 centres were enrolled in the pivotal trial. Patients were then randomly assigned to receive CellCept (3000mg/day) or azathioprine (1.5-3.0 mg/kg/day), in addition to cyclosporine and corticosteroids.

    IVUS resul

  • Contact: Cendrine Banerjee-Quetel

    Page: 1 2 3

    Related medicine news :

    1. New data supports CellCepts position as a world leader in solid organ transplantation
    2. Ibuprofen could reduce cardioprotective effect of aspirin
    3. Research targets biologic profile of obesity
    4. Research study profiles indoor tanners
    5. Jefferson researchers discover novel gene profile that may identify colon stem cells
    6. Comprehensive gene profiles hold promise for improving outcome of pediatric leukemia
    7. UCLA researchers release profile of proposition 36-eligible drug offenders
    8. Diabetic women on hormone replacement therapy have better glycemic and lipid profiles
    9. Gene expression profiles predict survival of lymphoma patients after chemotherpy
    10. Jefferson scientist sees drug profiles and tailor-made therapies as ways to beat HIV resistance

    Post Your Comments:

    (Date:8/31/2020)... ... 31, 2020 , ... Just found out your dear friend has cancer? , It’s hard to ... family member shares their diagnosis. Once the shock wears off, the questions and fears can ... are the best ways to help? Words are failing me. I’m scared. I want to ...
    (Date:8/31/2020)... ... August 31, 2020 , ... Smile Brands Inc., one of ... United States, today announced the grand opening of another affiliated Bright Now! ... enjoy convenient hours, a comfortable office, and full-service care at the new Beaumont ...
    (Date:8/31/2020)... ... August 31, 2020 , ... ... outcomes for patients with advanced heart failure, today announced that the company has ... amount of $555,358 from the National Heart, Lung, and Blood Institute of the ...
    (Date:8/28/2020)... ... August 28, 2020 , ... With in-person gluten-free events ... continue helping the specialty-diet community connect with great, gluten-free brands. At the ... giveaways, chat with brands & watch over 50 educational classes... all online from ...
    (Date:8/27/2020)... ... August 27, 2020 , ... The team at Sikara ... and wellness retreat. The practice is centered on results and providing the ultimate ... , Designed to be a sanctuary for total body renewal and aesthetic revitalization, ...
    Breaking Medicine News(10 mins):
    (Date:8/27/2020)... Fla. (PRWEB) , ... August 27, 2020 , ... Bridge ... of Directors. Dr. Friedman is an adult and pediatric neuro-oncologist who serves on the ... and as an educator at Duke University Medical School. , Internationally recognized, Dr. Friedman ...
    (Date:8/26/2020)... ... August 26, 2020 , ... ... BioPharma Services, Laboratory Testing division, expands its technology footprint with the addition ... Cytometry platforms available. With industry-leading biomarker solutions, complemented with traditional ligand-binding assays ...
    (Date:8/26/2020)... TULSA, Okla. (PRWEB) , ... August 26, 2020 ... ... DeAnna Looper, RN, CHPN, CHPCA, LNC has added CHC and CPCO to her ... the Board Certification in Healthcare Compliance (CHC) and the Certified Professional Compliance Officer ...
    Breaking Medicine Technology:
    Cached News: