HOME >> MEDICINE >> NEWS
Changes in ovaries could indicate higher risk of ovarian cancer

Currently, no accurate test for the early detection of ovarian cancer exists. Instead, ovarian cancer usually strikes quietly, becoming known to doctor and patient only after the disease has reached an advanced stage. But a new study in the April issue of Gynecologic Oncology suggests that certain cellular and molecular changes in the ovary could provide the warning signs needed for early detection. The study, "Premalignant lesions in the contralateral ovary of women with unilateral ovarian carcinoma," conducted by physicians at Temple University's School of Medicine and Temple University Hospital, compared the healthy ovaries of women with ovarian cancer to ovaries in women without cancer.

According to senior author Enrique Hernandez, M.D., professor and chair of obstetrics and gynecology at Temple, "Our study suggests that the 'normal' ovaries of women with ovarian cancer have not only structural changes, but also molecular changes that are less frequently found in the ovaries of healthy women," said Hernandez. The structural changes occurred in the cells of the ovary lining and the molecular changes involved higher levels of Bcl-2, a protein that prevents cell death.

Similar previous studies have been limited to women genetically predisposed to ovarian cancer.

"This study and others like it are building the foundation for better methods of early detection of ovarian cancer. If we are able to identify early changes along the path by which a normal ovarian cell turns into a cancerous ovarian cell, we might be able to develop a test to detect the disease earlier, even before it becomes cancerous," said Hernandez.

The researchers plan to conduct further testing to make sure the changes observed in this study are not the result of inflammation or injury to the ovary. They'd also like to test for other molecular markers, like Bcl-2, which could also indicate an increased risk of ovarian cancer.


'"/>

Contact: Eryn Jelesiewicz
eryn.jelesiewicz@temple.edu
215-707-0730
Temple University
6-Apr-2004


Page: 1

Related medicine news :

1. Changes needed to reduce migrant farm worker exposure to pesticides
2. Changes in allied and auxiliary health care workers training needed for quality of patient care, according to UCSF report
3. American Heart Association Comment: Contributions Of Trends In Survival And Coronary-Event Rates To Changes In Coronary Heart Disease Mortality
4. Psychologist Detects Brain-Activity Changes In Maltreated Kids
5. Changes In Levels Of LDLc From Pre- To Post-Menopausal Years Not Valuable Indicator Of Heart Disease, Reports University Of Pittsburgh Researcher
6. U-M Researcher Addresses Changes In The Heart As It Ages
7. Changes In Care Lower Costs Of Surgery To Prevent Stroke
8. Personality, Thought To Be Stable Over Time, Changes In Healthy People Who Take A Widely Used Anti-Depressant
9. Duke Study Uses Tiny Temperature Changes To Probe Water-Exclusion At Protein Binding Sites
10. Chemists Develop Probe To Detect Changes In Imaging Agents Inside Body
11. Removal of ovaries for young women with breast cancer and family history of ovarian cancer

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/21/2020)... ... May 21, 2020 , ... ... Clinical Research, CenterWatch eLearning , https://www.centerwatch.com/products/category/2764-elearning/product/472-the-crc-trainer , Wherever one falls ... Companion to the CRC’s Guide to Coordinating Clinical Research provides the perfect ...
(Date:5/21/2020)... ... May 21, 2020 , ... A Safe Haven Foundation (ASHF) has ... $5 million AbbVie COVID-19 Community Resilience Fund. The fund was created in March to ... frontline homeless workers in service to vulnerable populations in hard-hit communities. , “We ...
(Date:5/21/2020)... Mass. (PRWEB) , ... May 21, 2020 , ... ... of its award-winning population health management platform that supports care management and utilization ... than 100 individuals at client sites, TruCare 2020 provides significant usability and automation ...
(Date:5/16/2020)... CHARLOTTE, N.C. (PRWEB) , ... May 15, 2020 , ... On May 21, T1V will ... of the Ellison Institute of USC, and a contributor to CBS news, as we address ... been in place in most parts of the country since March, many questions are left ...
(Date:5/15/2020)... , ... May 15, 2020 , ... ... management solutions, recently announced the company and its healthcare-focused background screening division, PreCheck, ... 10 Pre-Employment Screening Consulting/Services Companies 2020. A distinguished panel comprising of CEOs, CIOs, ...
Breaking Medicine News(10 mins):
(Date:5/21/2020)... ... May 21, 2020 , ... Latham Pool Products Aids I2m ... polymer film gowns that will be worn by doctors and nurses , Latham ... accessories, is excited to give back to the community in a collaborative effort ...
(Date:5/21/2020)... ... 2020 , ... After The World Health Organization officially declared ... to continue seeing patients despite lockdowns and stay at home orders. According to ... complete healthcare communications, conducted online by The Harris Poll among more than 2,000 ...
(Date:5/21/2020)... ... ... Cataract is the world's leading cause of blindness , accounting for approximately ... more than 25 million Americans are estimated to have cataract, according to the report ... the population in America continues to age, the number of cataract cases are projected ...
Breaking Medicine Technology:
Cached News: