HOME >> MEDICINE >> NEWS
Changes in ovaries could indicate higher risk of ovarian cancer

Currently, no accurate test for the early detection of ovarian cancer exists. Instead, ovarian cancer usually strikes quietly, becoming known to doctor and patient only after the disease has reached an advanced stage. But a new study in the April issue of Gynecologic Oncology suggests that certain cellular and molecular changes in the ovary could provide the warning signs needed for early detection. The study, "Premalignant lesions in the contralateral ovary of women with unilateral ovarian carcinoma," conducted by physicians at Temple University's School of Medicine and Temple University Hospital, compared the healthy ovaries of women with ovarian cancer to ovaries in women without cancer.

According to senior author Enrique Hernandez, M.D., professor and chair of obstetrics and gynecology at Temple, "Our study suggests that the 'normal' ovaries of women with ovarian cancer have not only structural changes, but also molecular changes that are less frequently found in the ovaries of healthy women," said Hernandez. The structural changes occurred in the cells of the ovary lining and the molecular changes involved higher levels of Bcl-2, a protein that prevents cell death.

Similar previous studies have been limited to women genetically predisposed to ovarian cancer.

"This study and others like it are building the foundation for better methods of early detection of ovarian cancer. If we are able to identify early changes along the path by which a normal ovarian cell turns into a cancerous ovarian cell, we might be able to develop a test to detect the disease earlier, even before it becomes cancerous," said Hernandez.

The researchers plan to conduct further testing to make sure the changes observed in this study are not the result of inflammation or injury to the ovary. They'd also like to test for other molecular markers, like Bcl-2, which could also indicate an increased risk of ovarian cancer.


'"/>

Contact: Eryn Jelesiewicz
eryn.jelesiewicz@temple.edu
215-707-0730
Temple University
6-Apr-2004


Page: 1

Related medicine news :

1. Changes needed to reduce migrant farm worker exposure to pesticides
2. Changes in allied and auxiliary health care workers training needed for quality of patient care, according to UCSF report
3. American Heart Association Comment: Contributions Of Trends In Survival And Coronary-Event Rates To Changes In Coronary Heart Disease Mortality
4. Psychologist Detects Brain-Activity Changes In Maltreated Kids
5. Changes In Levels Of LDLc From Pre- To Post-Menopausal Years Not Valuable Indicator Of Heart Disease, Reports University Of Pittsburgh Researcher
6. U-M Researcher Addresses Changes In The Heart As It Ages
7. Changes In Care Lower Costs Of Surgery To Prevent Stroke
8. Personality, Thought To Be Stable Over Time, Changes In Healthy People Who Take A Widely Used Anti-Depressant
9. Duke Study Uses Tiny Temperature Changes To Probe Water-Exclusion At Protein Binding Sites
10. Chemists Develop Probe To Detect Changes In Imaging Agents Inside Body
11. Removal of ovaries for young women with breast cancer and family history of ovarian cancer

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/23/2019)... ... May 23, 2019 , ... Spicy Lingerie, one of the largest ... Memorial Day Weekend at SpicyLingerie.com . With discounts up to 80% off site-wide ... the best on offer throughout the weekend. , Eighty percent discounts can be ...
(Date:5/23/2019)... ... May 23, 2019 , ... Thermal Product ... Gruenberg Cleanroom Truck-In Ovens to the Medical Industry. , These Gruenberg walk-in ovens ... x 48” D x 72” H. The Gruenberg truck-in ovens were constructed from ...
(Date:5/23/2019)... JOSE, Calif. (PRWEB) , ... May 23, 2019 , ... ... IP Cores seamlessly integrated with its MIPI C-PHY v.1.2 IP supporting speeds of ... lane) and D-PHY v2.0 supporting speeds of upto 4.5 Gbps data rate per lane. ...
(Date:5/23/2019)... ... 2019 , ... More than 25 million Americans are estimated to have ... of light into the eye. Prevent Blindness , the nation’s oldest eye health ... public on risk factors, symptoms and treatment options. , Most cataracts are caused ...
(Date:5/23/2019)... ... May 23, 2019 , ... ... training, and technology to make software secure, is proud to announce that they ... Security Compass received this honor after a thorough and independent analysis conducted by ...
Breaking Medicine News(10 mins):
(Date:5/23/2019)... ... May 23, 2019 , ... IntelliSoft ... as well as a NCQA-certified credentials verification organization (CVO), will feature information on ... California Association of Medical Staff Services (CAMSS) on May 23-24, 2019 ...
(Date:5/22/2019)... ... May 22, 2019 , ... Southern Illinois University Edwardsville’s Mark Luer, PharmD, ... has served as interim dean since July 2018. The appointment is subject to SIU ... record of accomplishment during Dr. Luer’s service as interim dean, and we are excited ...
(Date:5/22/2019)... (PRWEB) , ... May 22, 2019 , ... ... event in its AppNexus office at 28 West 23rd Street from 6-9 pm ... by Give Beauty Wings, will feature compelling storytelling from diverse, honest perspectives on ...
Breaking Medicine Technology:
Cached News: