HOME >> MEDICINE >> NEWS
Chemical engineers suggest Alzheimer's onset tied To cholesterol, brain chemicals

COLLEGE STATION, December 6 - Few people can look Alzheimer's disease in the face without flinching. Alzheimer's takes from people the things they value most: intellect, emotion, independence, hope -- and eventually, life itself.

Now, a group of unlikely Alzheimer's researchers -- chemical engineers in Texas A&M University's Dwight Look College of Engineering -- are developing new understanding of how the disease robs Alzheimer's sufferers of their memory and reason. They've also found hints of new ways to eventually prevent its onset.

Laboratory studies conducted by chemical engineer Theresa Good, an Assistant professor in the Department of Chemical Engineering, and Ph.D. students Dawn L. Rymer and Steven S. Wang, suggest that Alzheimer's onset and the damage it causes to memory and cognitive abilities are tied to two substances: cholesterol (the same cholesterol doctors say people have too much of) and a complex chemical called ganglioside GM-1 -- found in the brain cells it attacks.

Their work centers on an important characteristic of Alzheimer's disease, a build-up of masses of protein, known as senile plaques. These plaques attach, or bind, to neurons -- specialized cells that allow information to move from place to place in the brain. When the plaques attach to the neurons, it causes a biochemical process to begin that eventually kills the neurons. Loss of neurons is what brings on the disease's characteristic loss of memory and cognitive abilities. High levels of either cholesterol or ganglioside GM-1 seem to make it easy for the plaques to attach to neurons.

The good news is that Good's research also suggests that reducing the amount of either cholesterol or ganglioside GM-1 interferes with the plaque's ability to attach to the neurons. In fact, simply reducing the amount of cholesterol in the cells seems to block attachment by almost all of the
'"/>

Contact: Mark Evans
mark-evans@tamu.edu
979-458-3597
Texas A&M University
6-Dec-2001


Page: 1 2

Related medicine news :

1. Chemical decoy shows promise for slowing Alzheimers by acting as decoy
2. Chemicals in tattoo inks need closer scrutiny
3. Chemicals in apples could reduce the risk of breast cancer, Cornell study in rats suggests
4. Chemicals found in cherries may help fight diabetes
5. Chemical cousin of anti-anxiety drugs holds promise for psoriasis treatment
6. Health benefits of citrus topic at American Chemical Society meeting in Philadelphia
7. Chemical brain scans may help reassure brain tumor patients
8. US DoE awards $4 million in funding to Stevens Center for MicroChemical Systems
9. Chemical & Engineering News 80th anniversary issue highlights periodic table
10. Chemical turns stem cells into neurons say scientists at Scripps Research Institute
11. Brookhaven spotlights: News from the March 2003 American Chemical Society Meeting

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/11/2019)... ... September 11, 2019 , ... Workplace injuries cost individuals, organisations ... injury risks which lead to musculoskeletal disorders (MSDs). , Starting with the ... team at Soter Analytics helps avoid ergonomic injury by coaching workers ...
(Date:9/11/2019)... ... September 11, 2019 , ... ... September 11-14 in Minneapolis at the Mall of America Radisson Blu. Four experts ... faculty members for the high-profile, knee-focused conference, which brings together more than 100 ...
(Date:9/11/2019)... GULF BREEZE, Fla. (PRWEB) , ... September 11, 2019 , ... ... what has caused damage or injury to the body. , Methamphetamine permanently harms the ... it. Through autopsies, doctors are getting a better understanding of how the damage occurs. ...
(Date:9/11/2019)... Calif. (PRWEB) , ... September 11, 2019 , ... Executives ... and magnitude of change in the healthcare industry over the past several years has ... a lot worse. The future of healthcare in America will depend largely on how ...
(Date:9/11/2019)... ... 10, 2019 , ... Four Shriners for Children Medical Center ... recognized among the best doctors in the San Gabriel Valley for providing high-quality, ... H. Cho, M.D. – Chief of Staff, scoliosis, spinal deformity surgery, limb deformity, ...
Breaking Medicine News(10 mins):
(Date:9/14/2019)... ... September 14, 2019 , ... On September 11, ... mesothelioma, a jury in Middlesex County found Johnson & Johnson liable for causing ... mesotheliomas were caused by asbestos-containing J&J talc products. , A unanimous ...
(Date:9/12/2019)... ... September 12, 2019 , ... ... EHR , revenue cycle management services, integrated practice management, and patient engagement ... Grand Sponsor at National User Conference (NUCON) 2019 . The annual ...
(Date:9/11/2019)... ... September 12, 2019 , ... ... and Best Practices, An FDAnews Webinar, Thursday, Sept. 26, 2019, 1:30-3:00 p.m. EDT, ... Act’s (DSCSA) implementation requirements? Is the company clear on nuances of the guidelines ...
Breaking Medicine Technology:
Cached News: