HOME >> MEDICINE >> NEWS
Chemical engineers suggest Alzheimer's onset tied To cholesterol, brain chemicals

COLLEGE STATION, December 6 - Few people can look Alzheimer's disease in the face without flinching. Alzheimer's takes from people the things they value most: intellect, emotion, independence, hope -- and eventually, life itself.

Now, a group of unlikely Alzheimer's researchers -- chemical engineers in Texas A&M University's Dwight Look College of Engineering -- are developing new understanding of how the disease robs Alzheimer's sufferers of their memory and reason. They've also found hints of new ways to eventually prevent its onset.

Laboratory studies conducted by chemical engineer Theresa Good, an Assistant professor in the Department of Chemical Engineering, and Ph.D. students Dawn L. Rymer and Steven S. Wang, suggest that Alzheimer's onset and the damage it causes to memory and cognitive abilities are tied to two substances: cholesterol (the same cholesterol doctors say people have too much of) and a complex chemical called ganglioside GM-1 -- found in the brain cells it attacks.

Their work centers on an important characteristic of Alzheimer's disease, a build-up of masses of protein, known as senile plaques. These plaques attach, or bind, to neurons -- specialized cells that allow information to move from place to place in the brain. When the plaques attach to the neurons, it causes a biochemical process to begin that eventually kills the neurons. Loss of neurons is what brings on the disease's characteristic loss of memory and cognitive abilities. High levels of either cholesterol or ganglioside GM-1 seem to make it easy for the plaques to attach to neurons.

The good news is that Good's research also suggests that reducing the amount of either cholesterol or ganglioside GM-1 interferes with the plaque's ability to attach to the neurons. In fact, simply reducing the amount of cholesterol in the cells seems to block attachment by almost all of the
'"/>

Contact: Mark Evans
mark-evans@tamu.edu
979-458-3597
Texas A&M University
6-Dec-2001


Page: 1 2

Related medicine news :

1. Chemical decoy shows promise for slowing Alzheimers by acting as decoy
2. Chemicals in tattoo inks need closer scrutiny
3. Chemicals in apples could reduce the risk of breast cancer, Cornell study in rats suggests
4. Chemicals found in cherries may help fight diabetes
5. Chemical cousin of anti-anxiety drugs holds promise for psoriasis treatment
6. Health benefits of citrus topic at American Chemical Society meeting in Philadelphia
7. Chemical brain scans may help reassure brain tumor patients
8. US DoE awards $4 million in funding to Stevens Center for MicroChemical Systems
9. Chemical & Engineering News 80th anniversary issue highlights periodic table
10. Chemical turns stem cells into neurons say scientists at Scripps Research Institute
11. Brookhaven spotlights: News from the March 2003 American Chemical Society Meeting

Post Your Comments:
(Date:7/28/2014)... York, NY (PRWEB) July 28, 2014 ... the body and it’s considered to be conditionally essential ... stress and is an advanced recovery & Immune System ... all the glutamine your body produces, supplementing with additional ... removal of waste products in the body, digestion and ...
(Date:7/28/2014)... Ticket Down is a dependable ... Miami, FL at the Sun Life Stadium in early September. ... Argentina and Brazil has is one that has continues to ... are forming on a consistent basis. The rivalry between ... in the recent 2014 World Cup. To the delight ...
(Date:7/28/2014)... chronic medical conditions people have at retirement age, the ... claims. Since nearly four in five older ... Bloomberg School of Public Health in Baltimore said the ... are slowing in the United States. "Living with ... heart failure is now the norm and not the ...
(Date:7/28/2014)... News) -- Endurance runners are far more likely to ... according to a new study. The researchers ... warm climates are actually 10 times more likely to ... common sudden death of a young and apparently healthy ... irregular heartbeat, often gets a lot more media attention. ...
(Date:7/28/2014)... Most cells do not divide unless there is enough ... cells and other cell types circumvent this rule. Researchers ... mechanism that overrides the cells, warning signals, enabling cancers ... supply. In the process, the researchers found that lysosomes ... cell division decisions. They also uncovered new evidence that ...
Breaking Medicine News(10 mins):Health News:Betancourt Nutrition Introduces Glutamine Plus with Sustamine® L-Alanyl-L-Glutamine 2Health News:Betancourt Nutrition Introduces Glutamine Plus with Sustamine® L-Alanyl-L-Glutamine 3Health News:Brazil vs. Colombia Tickets in Miami: Ticket Down Slashes Colombia vs. Brazil Tickets at Sun Life Stadium in Miami for Sept. 5th Showdown 2Health News:Brazil vs. Colombia Tickets in Miami: Ticket Down Slashes Colombia vs. Brazil Tickets at Sun Life Stadium in Miami for Sept. 5th Showdown 3Health News:Chronic Medical Conditions Can Shorten Seniors' Lives: Study 2Health News:Heat Stroke a Greater Threat to Endurance Runners Than Heart Problems: Study 2Health News:Cell's recycling center implicated in division decisions 2
(Date:7/28/2014)... July 28, 2014  Dignity Health St. Mary,s ... the Get With The Guidelines®-Stroke Silver-Plus Quality Achievement ... by the American Heart Association/American Stroke Association for ... number four cause of death and a leading ... United States , according to the American ...
(Date:7/28/2014)... , July 28, 2014 Reportbuyer.com has ... Global Bone Densitometers Market 2014-2018 ... bone densitometry scan is a special type of X-ray ... bone. It is used primarily to detect osteopenia or ... and the risk of fractures is high. The purpose ...
(Date:7/28/2014)... 28, 2014 Reportlinker.com announces that a ... catalogue: Portugal Pharmaceuticals and Healthcare ... http://www.reportlinker.com/p0207141/Portugal-Pharmaceuticals-and-Healthcare-Report-Q3-2014.html Includes 3 FREE ... economic growth last quarter has led us to ... As forecast previously, BMI expects Portugal,s ...
Breaking Medicine Technology:Dignity Health St. Mary's Medical Center Honored with Quality Achievement Award for Stroke Care 2Dignity Health St. Mary's Medical Center Honored with Quality Achievement Award for Stroke Care 3Global Bone Densitometers Market 2014-2018 2Global Bone Densitometers Market 2014-2018 3Global Bone Densitometers Market 2014-2018 4Global Bone Densitometers Market 2014-2018 5Portugal Pharmaceuticals and Healthcare Report Q3 2014 2Portugal Pharmaceuticals and Healthcare Report Q3 2014 3Portugal Pharmaceuticals and Healthcare Report Q3 2014 4
Cached News: