HOME >> MEDICINE >> NEWS
Chemical engineers suggest Alzheimer's onset tied To cholesterol, brain chemicals

COLLEGE STATION, December 6 - Few people can look Alzheimer's disease in the face without flinching. Alzheimer's takes from people the things they value most: intellect, emotion, independence, hope -- and eventually, life itself.

Now, a group of unlikely Alzheimer's researchers -- chemical engineers in Texas A&M University's Dwight Look College of Engineering -- are developing new understanding of how the disease robs Alzheimer's sufferers of their memory and reason. They've also found hints of new ways to eventually prevent its onset.

Laboratory studies conducted by chemical engineer Theresa Good, an Assistant professor in the Department of Chemical Engineering, and Ph.D. students Dawn L. Rymer and Steven S. Wang, suggest that Alzheimer's onset and the damage it causes to memory and cognitive abilities are tied to two substances: cholesterol (the same cholesterol doctors say people have too much of) and a complex chemical called ganglioside GM-1 -- found in the brain cells it attacks.

Their work centers on an important characteristic of Alzheimer's disease, a build-up of masses of protein, known as senile plaques. These plaques attach, or bind, to neurons -- specialized cells that allow information to move from place to place in the brain. When the plaques attach to the neurons, it causes a biochemical process to begin that eventually kills the neurons. Loss of neurons is what brings on the disease's characteristic loss of memory and cognitive abilities. High levels of either cholesterol or ganglioside GM-1 seem to make it easy for the plaques to attach to neurons.

The good news is that Good's research also suggests that reducing the amount of either cholesterol or ganglioside GM-1 interferes with the plaque's ability to attach to the neurons. In fact, simply reducing the amount of cholesterol in the cells seems to block attachment by almost all of the
'"/>

Contact: Mark Evans
mark-evans@tamu.edu
979-458-3597
Texas A&M University
6-Dec-2001


Page: 1 2

Related medicine news :

1. Chemical decoy shows promise for slowing Alzheimers by acting as decoy
2. Chemicals in tattoo inks need closer scrutiny
3. Chemicals in apples could reduce the risk of breast cancer, Cornell study in rats suggests
4. Chemicals found in cherries may help fight diabetes
5. Chemical cousin of anti-anxiety drugs holds promise for psoriasis treatment
6. Health benefits of citrus topic at American Chemical Society meeting in Philadelphia
7. Chemical brain scans may help reassure brain tumor patients
8. US DoE awards $4 million in funding to Stevens Center for MicroChemical Systems
9. Chemical & Engineering News 80th anniversary issue highlights periodic table
10. Chemical turns stem cells into neurons say scientists at Scripps Research Institute
11. Brookhaven spotlights: News from the March 2003 American Chemical Society Meeting

Post Your Comments:
(Date:3/3/2015)... US Air Purifiers LLC , an ... is pleased to announce that all Rabbit brand air purifiers ... to the west coast port strikes. This news comes just ... , The port strikes, which have caused ... quarter economic growth by as much as 1%, have hindered ...
(Date:3/3/2015)... Rhinebeck, NY (PRWEB) March 03, 2015 Topical ... held as a webinar streamed live on Tuesday, March 10th, ... workshops will be archived and accessible 24/7. ... the public. The topic for the March 10th workshop is ... timely discussion, considering that the U.S. represents 5% of the ...
(Date:3/3/2015)... 03, 2015 The combinatorial, multi-gene ... antidepressant treatment outcomes for patients with depression, and ... of the individual genes that comprise the test, ... the Mayo Clinic and Assurex Health, and published ... The proprietary technology of the GeneSight Psychotropic test ...
(Date:3/3/2015)... (PRWEB) March 03, 2015 -- vRad ( Virtual Radiologic ... today announced that Arlene Sussman, MD, a highly regarded ... live webinar to explore how telemedicine best practices allow ... services for women virtually anywhere. Click here ... Line” on March 4, 2015 at 1:00 pm CT. ...
(Date:3/3/2015)... In a segment that aired Monday, March ... Vedantam shared research from the Wharton School ... hand-hygiene compliance that occurs over the course of a healthcare ... in part by alerts on healthcare workers’ badges that remind ... a patient’s room. , “Over the course of a ...
Breaking Medicine News(10 mins):Health News:Rabbit Air Purifiers Back In Stock at US Air Purifiers LLC 2Health News:Rabbit Air Purifiers Back In Stock at US Air Purifiers LLC 3Health News:Topical BioMedics Hosts March Pain Management Webinar 2Health News:Topical BioMedics Hosts March Pain Management Webinar 3Health News:Topical BioMedics Hosts March Pain Management Webinar 4Health News:Topical BioMedics Hosts March Pain Management Webinar 5Health News:GeneSight Multi-Gene Combinatorial Pharmacogenomic (CPGx™) Test is More Predictive of Antidepressant Response than Single Gene Tests 2Health News:GeneSight Multi-Gene Combinatorial Pharmacogenomic (CPGx™) Test is More Predictive of Antidepressant Response than Single Gene Tests 3Health News:GeneSight Multi-Gene Combinatorial Pharmacogenomic (CPGx™) Test is More Predictive of Antidepressant Response than Single Gene Tests 4Health News:GeneSight Multi-Gene Combinatorial Pharmacogenomic (CPGx™) Test is More Predictive of Antidepressant Response than Single Gene Tests 5Health News:GeneSight Multi-Gene Combinatorial Pharmacogenomic (CPGx™) Test is More Predictive of Antidepressant Response than Single Gene Tests 6Health News:Latest vRad Webinar: Building World-Class Breast Imaging Services Virtually Anywhere with Telemedicine Best Practices 2Health News:Latest vRad Webinar: Building World-Class Breast Imaging Services Virtually Anywhere with Telemedicine Best Practices 3Health News:Latest vRad Webinar: Building World-Class Breast Imaging Services Virtually Anywhere with Telemedicine Best Practices 4Health News:BIOVIGIL Hygiene Technologies Answers Call for Hand Hygiene Alerts on Badges 2Health News:BIOVIGIL Hygiene Technologies Answers Call for Hand Hygiene Alerts on Badges 3
(Date:3/3/2015)... , Mar. 03, 2015 Research and Markets ... addition of the "Telemedicine and Mobile Healthcare ... 2015 - 2020" report to their offering. ... Health are all terms that pertain to the ... to provide remote clinical/non-clinical healthcare services. They form ...
(Date:3/3/2015)... -- Cyberonics, Inc. (NASDAQ: CYBX ), a global ... of epilepsy, today announced it will participate in the ... in Miami . ... will speak at 1:05 PM Eastern Time.  The session ... no formal materials will be presented.  A live audio ...
(Date:3/3/2015)... , March 3, 2015 Today, the ... sponsored by America,s biopharmaceutical research companies, unveiled a ... functionality to provide patients and caregivers with faster, ... public and private patient assistance programs. ... provided a platform to engage, educate and empower ...
Breaking Medicine Technology:Global Telemedicine and Mobile Healthcare Solutions, Services, and Devices: Market Analysis and Forecasts 2015 - 2020 2Global Telemedicine and Mobile Healthcare Solutions, Services, and Devices: Market Analysis and Forecasts 2015 - 2020 3Partnership for Prescription Assistance Relaunches Website with New Features for Patients and Caregivers 2
Cached News: