HOME >> MEDICINE >> NEWS
Chemical engineers suggest Alzheimer's onset tied To cholesterol, brain chemicals

COLLEGE STATION, December 6 - Few people can look Alzheimer's disease in the face without flinching. Alzheimer's takes from people the things they value most: intellect, emotion, independence, hope -- and eventually, life itself.

Now, a group of unlikely Alzheimer's researchers -- chemical engineers in Texas A&M University's Dwight Look College of Engineering -- are developing new understanding of how the disease robs Alzheimer's sufferers of their memory and reason. They've also found hints of new ways to eventually prevent its onset.

Laboratory studies conducted by chemical engineer Theresa Good, an Assistant professor in the Department of Chemical Engineering, and Ph.D. students Dawn L. Rymer and Steven S. Wang, suggest that Alzheimer's onset and the damage it causes to memory and cognitive abilities are tied to two substances: cholesterol (the same cholesterol doctors say people have too much of) and a complex chemical called ganglioside GM-1 -- found in the brain cells it attacks.

Their work centers on an important characteristic of Alzheimer's disease, a build-up of masses of protein, known as senile plaques. These plaques attach, or bind, to neurons -- specialized cells that allow information to move from place to place in the brain. When the plaques attach to the neurons, it causes a biochemical process to begin that eventually kills the neurons. Loss of neurons is what brings on the disease's characteristic loss of memory and cognitive abilities. High levels of either cholesterol or ganglioside GM-1 seem to make it easy for the plaques to attach to neurons.

The good news is that Good's research also suggests that reducing the amount of either cholesterol or ganglioside GM-1 interferes with the plaque's ability to attach to the neurons. In fact, simply reducing the amount of cholesterol in the cells seems to block attachment by almost all of the
'"/>

Contact: Mark Evans
mark-evans@tamu.edu
979-458-3597
Texas A&M University
6-Dec-2001


Page: 1 2

Related medicine news :

1. Chemical decoy shows promise for slowing Alzheimers by acting as decoy
2. Chemicals in tattoo inks need closer scrutiny
3. Chemicals in apples could reduce the risk of breast cancer, Cornell study in rats suggests
4. Chemicals found in cherries may help fight diabetes
5. Chemical cousin of anti-anxiety drugs holds promise for psoriasis treatment
6. Health benefits of citrus topic at American Chemical Society meeting in Philadelphia
7. Chemical brain scans may help reassure brain tumor patients
8. US DoE awards $4 million in funding to Stevens Center for MicroChemical Systems
9. Chemical & Engineering News 80th anniversary issue highlights periodic table
10. Chemical turns stem cells into neurons say scientists at Scripps Research Institute
11. Brookhaven spotlights: News from the March 2003 American Chemical Society Meeting

Post Your Comments:
(Date:8/29/2015)... ... 29, 2015 , ... Next weekend is Labor Day weekend, the last bash ... September 22nd this year). For IT security personnel, it should also mark the perfect ... far more costly than a simple headache. , Joe Caruso, founder and CEO-CTO of ...
(Date:8/29/2015)... New York, NY (PRWEB) , ... August 29, ... ... consistently successful results and include treating the localized area with stretching, soft tissue ... and a neutral pelvic position have shown through research to improve treatment ...
(Date:8/28/2015)... ... August 29, 2015 , ... Rio Salado College joined nine ... experience as part of the EDUCAUSE - Next Generation Learning Challenges 2015 Breakthrough Models ... the third Breakthrough Models Incubator hosted by EDUCAUSE and NGLC, which is ...
(Date:8/28/2015)... ... August 28, 2015 , ... Approximately 2,000 United Methodists ... celebrate children helping children, a thank you to the many creative and generous ... to the United Methodist initiative to end malaria deaths. , The Columbus Zoo ...
(Date:8/28/2015)... ... August 28, 2015 , ... With the goal of furthering ... the second year to the Adams County Fairgrounds in Mendon, IL on May 30th, ... money to support music education in the underfunded school districts of Mendon and its ...
Breaking Medicine News(10 mins):Health News:Business Cyber Security – Come Out of the Summer with a Clean Slate 2Health News:Business Cyber Security – Come Out of the Summer with a Clean Slate 3Health News:Business Cyber Security – Come Out of the Summer with a Clean Slate 4Health News:NEW APPROACH for Treatment of Recurrent Hamstring Strains and Hamstring Tendinosis is Available for the First Time in NYC 2Health News:NEW APPROACH for Treatment of Recurrent Hamstring Strains and Hamstring Tendinosis is Available for the First Time in NYC 3Health News:Rio Salado College Joins 9 Educational Leaders to Reinvent Higher Learning 2Health News:Rio Salado College Joins 9 Educational Leaders to Reinvent Higher Learning 3Health News:Rio Salado College Joins 9 Educational Leaders to Reinvent Higher Learning 4Health News:Saturday’s United Methodist Event at Columbus Zoo Celebrates Imagine No Malaria 2Health News:Saturday’s United Methodist Event at Columbus Zoo Celebrates Imagine No Malaria 3Health News:Best Drug Rehabilitation Interviews Country-Rock Duo Highway Run at the 2015 "Music With A Mission" Benefit Concert 2
(Date:8/28/2015)... 2015 Patterson Medical, formerly the medical ... ), is now an independent company with today,s ... Medical by Madison Dearborn Partners (MDP).  ... a transition period before rebranding as the world,s ... products.  With the focused resources and expertise of ...
(Date:8/28/2015)... , August 28, 2015 The scientific ... collaboration with one of the leading academics in the field ... world record holder in life extension for model animals - ... biology of aging and age-related diseases, primarily, around the stability ... has just been published as "Stability analysis of a model ...
(Date:8/28/2015)... and PITTSBURGH , Aug. 28, ... today announced that its shareholders have approved Mylan,s ... PRGO ; TASE) and the related issuance of ... extraordinary general meeting of shareholders held today. The ... at the extraordinary general meeting. In addition, the ...
Breaking Medicine Technology:Patterson Medical Positioned for Continued Growth as a Newly Independent Company 2Patterson Medical Positioned for Continued Growth as a Newly Independent Company 3Gero: Physics Meets Biology to Help Defeat Aging 2Gero: Physics Meets Biology to Help Defeat Aging 3Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 2Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 3Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 4Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 5Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 6Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 7Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 8Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 9
Cached News: