Chemists Develop Probe To Detect Changes In Imaging Agents Inside Body

Cincinnati -- Chemists at the University of Cincinnati have found a way to determine what happens to medical imaging agents as they travel through the body and accumulate inside various tissues and organs.

The agents combine a radioactive tracer such as technetium with a ligand or compound that can target the tissue or organ of interest. For example, a common application is a heart imaging agent which can detect blockages in blood flow following a heart attack. This information is important to doctors planning follow- up therapy and rehabilitation.

"Doctors can get very good images this way," said Distinguished Research Professor William Heineman who has studied the fundamental chemistry of several heart, skeletal and brain imaging agents at UC. "You see bright regions where muscle tissue is normal and very dark areas where blood flow is blocked."

Heineman is an analytical chemist who also has a great deal of experience developing sensors which can detect compounds at extremely low concentrations, as low as 3,000 molecules. So, in his recent research, Heineman, chemistry professor Carl Seliskar, and chemistry graduate students decided to try to develop a sensor to see if they could monitor what happens to an imaging agent after it enters the body.

"We just happened to be in a unique position of knowing something about nuclear medicine and also about developing sensors. We're probably the only group in the world with those two skills."

The sensors are tiny carbon fibers, the same graphite fibers used to make lighter tennis rackets and golf clubs, coated with a thin layer of polymer. The package then becomes a probe which can be inserted directly into the heart tissue.

"We can get these fibers as free samples and simply take out a single fiber and make it into a sensor by coating it with the polymer that gives us the selectivity needed to detect the imaging agent in the presence of other compounds in tissue. Then we insert it into the

Contact: Chris Curran
University of Cincinnati

Page: 1 2 3

Related medicine news :

1. Chemists identify immune system mechanism for methamphetamine binges
2. Chemists synthesize molecule that helps body battle cancers, malaria
3. Chemists honor Heroes for biotechnology achievements in health
4. Chemists seek light-activated glue for vascular repair
5. Chemists create synthetic cytochromes
6. Chemists show proteins behave differently inside cells than they do in water solutions
7. Chemists take new approach to fighting resistance
8. Chemists Discover That Aerosol Clusters Play Larger Role In Generation Of Air Pollution
9. Over 6,000 Technical Presentations Will Reveal New Findings At National Chemists Meeting In Boston, August 23 - 27
10. Chemists Closing In On Commercial Potential Of Alkanes
11. Society for Research in Child Development (SRCD) biennial meeting

Post Your Comments:

(Date:9/1/2020)... ... 2020 , ... Feeding Matters , the first organization in the world ... is pleased to announce that the U.S. Centers for Disease Control and Prevention (CDC) ... next edition of the U.S. International Classification of Diseases (ICD ) on October ...
(Date:8/31/2020)... ... August 31, 2020 , ... ... organization devoted exclusively to funding innovative lymphoma research and serving the lymphoma community ... today announced the 10th Anniversary of Blood Cancer Awareness Month (BCAM) and its ...
(Date:8/31/2020)... ... August 31, 2020 , ... Genesis Chiropractic Software ... today the launch of its integrated, HIPAA compliant, telehealth solution, available to US-based ... in under 90 seconds. , According to the U.S. Department of Health ...
(Date:8/31/2020)... ... August 31, 2020 , ... A Cure for Covid-19 “PTS” with Mediation & Hypnosis ... planet are in a state of panic, experiencing deep anxiety, immense stress, and right now ... solution is timely when most people on the planet are experiencing a great degree of ...
(Date:8/29/2020)... ... August 29, 2020 , ... When professor and author Randy Pausch ... than most people would. Rather than become melancholic, however, he put together a final ... one’s dreams. Randy Pausch took a negative situation and turned it into something that ...
Breaking Medicine News(10 mins):
(Date:8/26/2020)... ... August 26, 2020 , ... Unscrupulous ... systems kill Coronavirus. While air purification technologies, including GreenTech Environmental’s proprietary methods, have ... Ebola, no air purification system has published results of singular and scientific testing ...
(Date:8/26/2020)... TULSA, Okla. (PRWEB) , ... August 26, 2020 ... ... DeAnna Looper, RN, CHPN, CHPCA, LNC has added CHC and CPCO to her ... the Board Certification in Healthcare Compliance (CHC) and the Certified Professional Compliance Officer ...
(Date:8/26/2020)... SAN DIEGO (PRWEB) , ... August 26, 2020 ... ... services, announced today the appointment of Claude E. Hooton as President and Chief ... the role of Executive Chairman of the company’s Board of Managers. , ...
Breaking Medicine Technology:
Cached News: