HOME >> MEDICINE >> NEWS
Chemists take new approach to fighting resistance

Chemists at Wayne State University have designed two new drugs to fight the growing problem of antibiotic resistance: an antibiotic that "self-destructs" after exposure to light and another that "self-regenerates" after encountering resistant bacteria. Both represent novel approaches for keeping infectious bacteria at bay, the researchers say.

Reports on the research will appear in two separate peer-reviewed publications of the American Chemical Society, the world's largest scientific society. The report on the regenerating antibiotic is in the Dec. 22 print edition of the Journal of the American Chemical Society; the self-destructive antibiotic is scheduled for the Jan. 13 print issue of the Journal of Medicinal Chemistry. Both articles were published this month-Dec. 4 and 16, respectively-on the journals' web sites.

Antibiotics are among the most widely prescribed drugs worldwide. Commonly used to fight infections in both humans and animals, these drugs have had a major impact on public health. Paradoxically, their widespread use has fueled a growing health threat: antibiotic resistance.

"Once bacteria are exposed to a given antibiotic, they become resistant to its action in due time by changing their own genetic make-up to cope with the challenge," explains lead researcher Shahriar Mobashery, Ph.D., professor of chemistry at Wayne State University in Detroit. "The longer the bacteria are exposed to a given antibiotic, the higher the likelihood they will eventually evolve a resistance to that antibiotic," Dr. Mobashery said.

Antibiotic resistance means that drugs that used to work against infections will no longer work effectively, putting people and animals at risk. For years, scientists have been searching for ways to resolve this growing problem. Now, they may have found a duo of answers.

"Self-destructive" Antibiotic

"A feature of antibiotics is that they are usually not metabolized in the
'"/>

Contact: Beverly Hassell
b_hassell@acs.org
202-872-4065
American Chemical Society
19-Dec-1999


Page: 1 2 3

Related medicine news :

1. Chemists identify immune system mechanism for methamphetamine binges
2. Chemists synthesize molecule that helps body battle cancers, malaria
3. Chemists honor Heroes for biotechnology achievements in health
4. Chemists seek light-activated glue for vascular repair
5. Chemists create synthetic cytochromes
6. Chemists show proteins behave differently inside cells than they do in water solutions
7. Chemists Discover That Aerosol Clusters Play Larger Role In Generation Of Air Pollution
8. Over 6,000 Technical Presentations Will Reveal New Findings At National Chemists Meeting In Boston, August 23 - 27
9. Chemists Closing In On Commercial Potential Of Alkanes
10. Chemists Develop Probe To Detect Changes In Imaging Agents Inside Body
11. OHSU scientists develop MRI approach to improve breast cancer detection

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/5/2016)... , ... February 05, 2016 , ... ... domestic franchisees of Popeyes Louisiana Kitchen restaurants, launched the 14th annual “Appetite for ... kids and adults with muscular dystrophy, ALS and related diseases that severely limit ...
(Date:2/5/2016)... Dickson, Tennessee (PRWEB) , ... February 05, 2016 ... ... State Community College President George H. Van Allen have signed a joint enrollment ... semester, provides a seamless pathway toward associate and baccalaureate degrees at FHU|Dickson. ...
(Date:2/5/2016)... ... February 05, 2016 , ... US Sports Camps , ... Dover, NH to direct high-performance kids yoga training. ChildLight Yoga Studio is centrally situated ... hour from Boston. , ChildLight Yoga Studio founder Lisa Flynn expresses her excitement, “We ...
(Date:2/5/2016)... ... February 05, 2016 , ... Regular gym users know the routine: each January, ... to access the treadmills. It’s a predictable trend. After the excesses of November and ... in shape by joining gyms, starting new walking or running routines, or signing up ...
(Date:2/5/2016)... ... February 05, 2016 , ... ... the 2015 Best in KLAS: Software & Services for HIT Implementation Support & ... KLAS report independently ranks vendor performance by healthcare executives, managers and clinicians representing ...
Breaking Medicine News(10 mins):
(Date:2/5/2016)... -- Aralez Pharmaceuticals Inc. ("Aralez") today announced the completion of ... Canada Inc. ("Tribute") following approval of the transaction by ... company will operate under Aralez Pharmaceuticals Inc. ("Aralez"), a ... Canada , Ireland and ... terms of the Agreement and Plan of Merger and ...
(Date:2/5/2016)... , Feb. 5, 2016 Dehaier ... Medical" or the "Company"), which develops, markets and ... in China and international ... plan which aims to concentrate the Company,s resources ... sleep respiratory business and to focus more on ...
(Date:2/5/2016)... PUNE, India , February 4, 2016 ... , Spain , UK, and Israel ... of Type 1, 2, and 3 GD, segmented by age and sex ... and PhD-level epidemiologists. The EpiCast Report is in-depth, high quality, transparent and ... France , Germany , ...
Breaking Medicine Technology:
Cached News: