HOME >> MEDICINE >> NEWS
Chemists take new approach to fighting resistance

Chemists at Wayne State University have designed two new drugs to fight the growing problem of antibiotic resistance: an antibiotic that "self-destructs" after exposure to light and another that "self-regenerates" after encountering resistant bacteria. Both represent novel approaches for keeping infectious bacteria at bay, the researchers say.

Reports on the research will appear in two separate peer-reviewed publications of the American Chemical Society, the world's largest scientific society. The report on the regenerating antibiotic is in the Dec. 22 print edition of the Journal of the American Chemical Society; the self-destructive antibiotic is scheduled for the Jan. 13 print issue of the Journal of Medicinal Chemistry. Both articles were published this month-Dec. 4 and 16, respectively-on the journals' web sites.

Antibiotics are among the most widely prescribed drugs worldwide. Commonly used to fight infections in both humans and animals, these drugs have had a major impact on public health. Paradoxically, their widespread use has fueled a growing health threat: antibiotic resistance.

"Once bacteria are exposed to a given antibiotic, they become resistant to its action in due time by changing their own genetic make-up to cope with the challenge," explains lead researcher Shahriar Mobashery, Ph.D., professor of chemistry at Wayne State University in Detroit. "The longer the bacteria are exposed to a given antibiotic, the higher the likelihood they will eventually evolve a resistance to that antibiotic," Dr. Mobashery said.

Antibiotic resistance means that drugs that used to work against infections will no longer work effectively, putting people and animals at risk. For years, scientists have been searching for ways to resolve this growing problem. Now, they may have found a duo of answers.

"Self-destructive" Antibiotic

"A feature of antibiotics is that they are usually not metabolized in the
'"/>

Contact: Beverly Hassell
b_hassell@acs.org
202-872-4065
American Chemical Society
19-Dec-1999


Page: 1 2 3

Related medicine news :

1. Chemists identify immune system mechanism for methamphetamine binges
2. Chemists synthesize molecule that helps body battle cancers, malaria
3. Chemists honor Heroes for biotechnology achievements in health
4. Chemists seek light-activated glue for vascular repair
5. Chemists create synthetic cytochromes
6. Chemists show proteins behave differently inside cells than they do in water solutions
7. Chemists Discover That Aerosol Clusters Play Larger Role In Generation Of Air Pollution
8. Over 6,000 Technical Presentations Will Reveal New Findings At National Chemists Meeting In Boston, August 23 - 27
9. Chemists Closing In On Commercial Potential Of Alkanes
10. Chemists Develop Probe To Detect Changes In Imaging Agents Inside Body
11. OHSU scientists develop MRI approach to improve breast cancer detection

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Chemists take new approach fighting resistance

(Date:1/22/2015)... TX (PRWEB) January 22, 2015 The Incredible ... Bodybuilder Ben Pakulski to increase lean muscle by up to ... has caught the attention of HealthyandFitZone.com’s Stan Stevenson, prompting an ... that it is a step-by-step, scientific diet formula that allows ...
(Date:1/22/2015)... Juvent Sports ( http://www.juventsports.com ) and David ... Show to bestow a Juvent Sports Achievement award upon ... McKitrick. The award commemorated and congratulated McKitrick for her ... won her first amateur tournament in 1979 and most ...
(Date:1/22/2015)... 2015 Carinsurancesavings.biz has released a new blog ... dismemberment insurance . , Purchasing an accidental death and ... advantageous. This type of rider provides benefits if the insured ... considered a lesser form of life insurance. , AD&D ...
(Date:1/22/2015)... IsoComforter, Inc. has introduced the most innovative ... design to treat specific body parts and muscle groups. , ... easy to use patented cold therapy machine with the innovative ... and muscle injuries. IsoComforter has become the industry leader ...
(Date:1/22/2015)... JJsHouse.com is a famous dress online store for ... its latest collection of wedding dresses , and launches ... is the wedding dress on your big day; the wedding ... Every bride wants to find the most suitable wedding dress. ...
Breaking Medicine News(10 mins):Health News:The Incredible Bulk: Review Examining Ben Pakulski’s Brand New Bulking Muscle Building Diet Program Released 2Health News:All-Time Leading Female Amateur Golfer Arlene McKitrick Receives Juvent Sports Achievement Award at 2015 PGA Show 2Health News:All-Time Leading Female Amateur Golfer Arlene McKitrick Receives Juvent Sports Achievement Award at 2015 PGA Show 3Health News:Accidental Death and Dismemberment Insurance Can Be Purchased at Low Prices Online 2Health News:IsoComforter Introduces Best of Class Cold Therapy Product to the Worldwide Market 2Health News:Find The Most Suitable Wedding Dress At JJsHouse.com 2
(Date:1/23/2015)... Iowa , Jan. 23, 2015  The Partnership to Fight Chronic ... health care leaders and a new study analyzing the ... The PFCD is a nationwide coalition working to educate policy makers ... released at the Capitol was focused on how the ...
(Date:1/23/2015)... , Jan. 23, 2015  Northwest Biotherapeutics, Inc. (NASDAQ: ... personalized immune therapies for operable and inoperable solid tumor cancers, ... at the 7 th Annual Phacilitate Immunotherapy Forum in ... presentation at Phacilitate will take place on January 26 at ...
(Date:1/23/2015)... a third of reproductive-aged women enrolled in Medicaid, and more ... prescription for an opioid pain medication each year during 2008-2012, ... Weekly Report (MMWR). Opioids are typically prescribed ... They are also found in some prescription cough medications. The ...
Breaking Medicine Technology:New research shows Iowa health exchange would benefit from improvements 2New research shows Iowa health exchange would benefit from improvements 3NW Bio To Present At The 7th Annual Phacilitate Immunotherapy Forum 2NW Bio To Present At The 7th Annual Phacilitate Immunotherapy Forum 3Opioid painkillers widely prescribed among reproductive age women 2Opioid painkillers widely prescribed among reproductive age women 3
Cached News: