Chemotherapy plus radiation therapy for head and neck cancer increases survival rates of some patients

Adding weekly chemotherapy to radiation therapy significantly increases survival rates of patients with advanced head and neck cancer, a new University of Maryland Medical Center study indicates. The study found a 48 percent three-year survival rate among patients who received the combined therapy. The results will be presented at the 41st Annual Meeting of the American Society for Therapeutic Radiology and Oncology (ASTRO) on November 1 in San Antonio, TX.

"The standard treatment for these patients is radiation therapy alone, says Mohan Suntharalingam, M.D., vice chair of the Department of Radiation Oncology at the University of Maryland Medical Center and assistant professor of radiation oncology at the University of Maryland School of Medicine. "At best, only 20 percent of these patients who cannot have surgery survive for five years. While there is no available data to show a three-year survival with just radiation therapy, it's probably closer to 30 percent. So adding chemotherapy represents a dramatic improvement in treatment," says Dr. Suntharalingam who is principal investigator.

Sixty patients were enrolled in the study. During the study, patients received weekly doses of two standard chemotherapy drugs, carboplatin and taxol, used together for the first time, in addition to radiation therapy five times a week for seven weeks. The patients in the study all had locally advanced cancer and/or cancer that had spread to nearby lymph nodes. Each patient was monitored to see if the cancer had responded to treatment. In 70 percent of the patients who had the combined treatment, there was complete remission of the disease. Patients were able to tolerate the combined treatment well with some side effects, including difficulty swallowing and skin irritation, says Dr. Suntharalingam.

Typically, people at highest risk of head and neck cancer are those who consume large amounts of alcohol and who smoke. There are more than 12,000 new case

Contact: Barbara Crawford
University of Maryland Medical Center

Page: 1 2

Related medicine news :

1. Chemotherapy, but not tamoxifen, associated with stroke risk after breast cancer treatment
2. Chemotherapy trial proves the worth of including elderly patients in clinical trials
3. Breakthrough New Therapy Uses Antibody-Targeted Chemotherapy To Fight Leukemia
4. Women Who Have Invasive Cervical Cancer Benefit From Addition Of Chemotherapy To Radiation Treatment
5. Discovery May Boost Effectiveness Of Chemotherapy
6. Promising New Drug Uses Antibody Targeted Chemotherapy To Fight Leukemia
7. BioNumerik Reports The Supercomputer Supported Discovery Of New, Non-Toxic Chemotherapy Protecting Agent
8. Better Survival For Women With Breast Cancer -New Evidence On Chemotherapy
9. Study shows risk of cardiac death after radiation for breast cancer has dramatically decreased
10. Combining PET and CT scans leads to more accurate radiation therapy for lung cancer patients
11. NASA awards $9.8 million NSCOR grant to UT Southwestern to study effects of space radiation exposure

Post Your Comments:

(Date:9/11/2019)... ... 11, 2019 , ... Executives at health systems and hospitals across America are ... over the past several years has been intense. For professionals and organizations that struggle ... America will depend largely on how these executives respond. Will they have the tools ...
(Date:9/11/2019)... ... September 10, 2019 , ... ... facing the ever-changing corporate landscape, Mediaplanet today announces the launch of its ... topics ranging from the importance of candid one-on-one conversations, ideas for improving ...
(Date:9/9/2019)... ... September 09, 2019 , ... ... Dentistry in Cornelius, NC, now welcome individuals with tooth loss in Davidson, NC ... with patients who have single or multiple missing teeth and want the advantages ...
(Date:9/9/2019)... ... September 09, 2019 , ... On September 6, 2019, ... on a diabetes-language movement (#LanguageMatters) to include oral and written language. The organization ... stigma, respectful and inclusive, empowering, and person-centered (to include care that is respectful ...
(Date:9/8/2019)... ... 2019 , ... The Southern Illinois University Edwardsville School of ... reached an all-time high with 1,778 students. , The SON’s enrollment features ... students. The total does not include an additional 30 undeclared graduate students, who ...
Breaking Medicine News(10 mins):
(Date:9/14/2019)... ... 14, 2019 , ... On September 11, 2019, after a ... in Middlesex County found Johnson & Johnson liable for causing the Plaintiffs’ cancers. ... by asbestos-containing J&J talc products. , A unanimous jury found that ...
(Date:9/12/2019)... ... September 12, 2019 , ... iPatientCare, a ... practice management, and patient engagement solutions, announced today the participation of Amazon ... (NUCON) 2019 . The annual conference features informative sessions about upcoming enhancements, ...
(Date:9/11/2019)... ... September 12, 2019 , ... Understanding the Drug ... FDAnews Webinar, Thursday, Sept. 26, 2019, 1:30-3:00 p.m. EDT, https://www.fdanews.com/understanding-the-dscsa , ... Is the company clear on nuances of the guidelines regulating the drug supply ...
Breaking Medicine Technology:
Cached News: