HOME >> MEDICINE >> NEWS
Chemotherapy trial proves the worth of including elderly patients in clinical trials

Doctors should be encouraged to include many more elderly people in clinical trials than they do at present, Dr Olavo Feher told the 3rd European Breast Cancer Conference in Barcelona today (Wednesday 20 March).

Dr. Feher, attending physician at the Hospital do Cancer in Sao Paulo, Brazil, said that the elderly were under-represented in clinical trials for cancer treatments, yet his research showed that useful results could be obtained if they were included in trials.

He said: Age is a known major risk factor for most cancers in adults. Approximately 50% of all new breast cancers occur in women aged 65 or older. However older women tend to be under-treated. Several clinical trials have shown that older women are less likely to receive post-operative radiation and systemic adjuvant therapy as compared to younger women. This population seems to be under-represented in clinical trials.

Dr. Feher told the conference that only women aged 60 or over were included in the randomized phase lll clinical trial that he and his colleagues co-ordinated in 18 countries world-wide*. The trial was performed to assess two chemotherapy agents (epirubicin and gemcitabine) as first-line, single agent treatments in elderly women with metastatic breast cancer. Both drugs are already known to be effective and well-tolerated in metastatic breast cancer, but it was not known how they would affect elderly women and what the correct doses should be. The median age of the women was 68 in the epirubicin arm of the trial and 69 in the gemcitabine arm of the trial.

Between October 1996 and February 1999, 397 women joined the trial. The results showed that both drugs were well tolerated, and that there were no differences in the womens quality of life between the two arms of the trial. Epirubicin proved to be more effective as the womens tumours responded better to it and their cancer did not start to progress again so quickly. The most common side effe
'"/>

Contact: Emma Mason
wordmason@aol.com
44-0-7711-296-986
Federation of European Cancer Societies
20-Mar-2002


Page: 1 2

Related medicine news :

1. Chemotherapy, but not tamoxifen, associated with stroke risk after breast cancer treatment
2. Chemotherapy plus radiation therapy for head and neck cancer increases survival rates of some patients
3. Breakthrough New Therapy Uses Antibody-Targeted Chemotherapy To Fight Leukemia
4. Women Who Have Invasive Cervical Cancer Benefit From Addition Of Chemotherapy To Radiation Treatment
5. Discovery May Boost Effectiveness Of Chemotherapy
6. Promising New Drug Uses Antibody Targeted Chemotherapy To Fight Leukemia
7. BioNumerik Reports The Supercomputer Supported Discovery Of New, Non-Toxic Chemotherapy Protecting Agent
8. Better Survival For Women With Breast Cancer -New Evidence On Chemotherapy
9. Lack of clinical trial participation may contribute to lower survival rates
10. Protecting children from industrial chemicals in the environment
11. Hopkins begins human trials with donor adult stem cells to repair muscle damaged from heart attack

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/21/2019)... ... August 21, 2019 , ... CBD has officially entered the ... this announcement is available at: https://youtu.be/D-65LmBhJhU , CBD, the non-intoxicating cannabis ... found on the internet, wellness catalogs, small specialty shops, and now, after announcing ...
(Date:8/21/2019)... ... August 21, 2019 , ... Photoprotective Technologies (PPT) has just received US patent ... currently used in skincare products such as creams or makeup and is distributed by ... need to protect the skin from blue light as well as UV. , ...
(Date:8/19/2019)... ... August 19, 2019 , ... Nearly ... Organic Skin Care products , the authorized retailer will change its corporate name ... practicing esthetician in Florida providing Eminence Organic Skin Care facials and treatments. DeVries ...
(Date:8/19/2019)... (PRWEB) , ... August 19, 2019 , ... Cosmetic Town, ... spotlight on the best hair restoration doctors in New York currently providing a lifetime ... as those starting to see some thinning hair. Cosmetic Town makes the process of ...
(Date:8/16/2019)... ... August 16, 2019 , ... Cannabinoid Biosciences ... non-pharmaceutical cannabidiol (CBD) products across the CBD market in the United States in ... campaign to raise $50 million on September 9, 2019. , Established on May ...
Breaking Medicine News(10 mins):
(Date:8/21/2019)... ... August 21, 2019 , ... Impact Advisors , a ... announced today that it has been named to Inc. magazine’s Inc. 5000 list. The ... for-profit companies with significant percentage revenue growth. This year the firm was also named ...
(Date:8/19/2019)... ... August 19, 2019 , ... Sheba ... the findings of research validating the clinical impact of MedAware’s machine learning-enabled patient ... August 2019 in the Journal of American Medical Informatics Association (JAMIA) ...
(Date:8/19/2019)... , ... August 19, 2019 , ... ... certification process to promote standards of excellence within the field of treatment for ... professional growth and communication with others who have a similar mission. , ...
Breaking Medicine Technology:
Cached News: