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Children achieve sustained ADHD symptom improvement with long-term, once-daily use of Adderall XR

ully monitored medication are more effective than those that do not, such as behavioral therapy alone. Medication should be considered part of an overall multi-modal treatment plan for ADHD.

Shire Pharmaceuticals Group plc
Shire Pharmaceuticals Group plc (Shire) is a rapidly growing international emerging pharmaceutical company with a strategic focus on four therapeutic areas central nervous system disorders (CNS), gastrointestinal (GI), oncology, and anti-infectives. Shire also has three platform technologies: advanced drug delivery, lead optimization for small molecules and Biologics. Shire's core strategy is based on research and development combined with in-licensing and a focus on eight key pharmaceutical markets.

The once-daily mixed salts amphetamine product is distributed in the United States by Shire US Inc., the sales and marketing subsidiary of Shire Pharmaceuticals, plc.

For further information on Shire, please visit the Company's website: www.shire.com; or www.adhdsupportcompany.com.


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Contact: Michle Roy, Shire Pharmaceuticals Group plc
450-978-7938
Porter Novelli
21-May-2003


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