Cholesterol Carriers Better Predictors Than Cholesterol For Second Heart Attack

DALLAS, May 18 -- Two proteins that carry cholesterol in the blood may provide a better way to measure heart attack risk than the usual cholesterol blood test, report researchers in today's Circulation: Journal of the American Heart Association.

"Because the two proteins are more sensitive heart disease risk detectors than cholesterol, they may identify more individuals at risk and one day replace cholesterol testing," says the study's lead author, Arthur J. Moss, M.D., professor of medicine (cardiology) at the University of Rochester Medical Center, Rochester, N.Y.

The association between the proteins -- apolipoprotein (apo) A-1 and apolipoprotein (apo) B -- and heart attack risk held true even in the presence of heart disease risk factors including, smoking, diabetes, high blood pressure and high blood levels of cholesterol.

(Apo) A-1 and apo B carry cholesterol in the bloodstream. Apo B is a cholesterol donor, while apo A-1 is a cholesterol scavenger.

Researchers also identified a third protein, D-dimer, which was associated with heart attack risk. D-dimer is a breakdown product in the blood when clots form. Elevated levels of D-dimer indicate excess clotting or coagulation activity in the blood.

Individuals with the blood protein profile of low apo A-1, high apo B, and high D-dimer levels were eight times more likely than others in the study to experience a second heart attack within two years, Moss says. Patients with an abnormal blood level of only one of these proteins were twice as likely to experience another heart attack within two years.

When apo B levels are high, apo B deposits cholesterol on the inside surface of the plaque. Then it moves into the plaque, thereby increasing the size of the fatty deposit. Ordinarily, apo A-1 would pick up these cholesterol deposits before they enter the plaque. However, if apo A-1 levels are low, the process does not go as expected. Instead, the cholesterol accumulates and for

Contact: Carole Bullock
American Heart Association

Page: 1 2 3

Related medicine news :

1. Cholesterol under-treated in high-risk women in managed care study
2. Cholesterol-lowering drug may also reduce risk of blood clots
3. Cholesterol-lowering drug may slow Alzheimers progression
4. Cholesterol-lowering medications may reduce risk of glaucoma
5. Cholesterol levels fluctuate with the seasons
6. Cholesterol-lowering drugs may help stroke patients get well
7. Cholesterol drugs may lower risk for mental impairment after stroke
8. Cholesterol drug increases pain-free walking distance
9. Cholesterol drug helps heart failure patients without high cholesterol
10. Cholesterol drug could lead to new therapy for multiple sclerosis
11. Cholesterol fighting drugs may also have protective effects against multiple sclerosis

Post Your Comments:
(Date:10/9/2015)... ... , ... "As a nurse, I care for male patients who struggle with ... large diapers or pads. We came up with this as a better alternative to ... from the tip of the penis. This prevents stains from forming on underwear and ...
(Date:10/9/2015)... (PRWEB) , ... October 09, 2015 , ... Santa Rosa ... their partnership as MD Anderson prepares to go-live on the Epic platform in March ... for early 2016. Santa Rosa will execute the contract by supporting Scheduling Appointment Conversion ...
(Date:10/9/2015)... , ... October 09, 2015 , ... Most people assume ... with more vegetables and less meat. While noted T’ai Chi Master and integrative medicine ... and Yang” relationship between the two cuisines and that they potentially complement one another, ...
(Date:10/9/2015)... ... 09, 2015 , ... The Kitchenistas of National City, a documentary film on ... conditions related to food, has been selected for viewing at the I Imagine Film ... Festival on October 30-31 in London, England. , The documentary, by San Diego filmmaker ...
(Date:10/9/2015)... ... 2015 , ... When the producers of the popular ‘Ask This Old House’ ... Hollywood, CA, they turned to a trusted resource in Tamarack Technologies. , “Our HV ... because of our successful past experience with the show they enlisted our help,” said ...
Breaking Medicine News(10 mins):
(Date:10/8/2015)... of investigation, Ross Feller Casey , LLP has filed ... Xarelto,s recommended dosage doesn,t work for as long as promised, ... on behalf of a Florida man ... as the manufacturer suggested. Ross Feller Casey is ... clients from across the country with similar claims. --> ...
(Date:10/8/2015)... , Oct. 08 2015 ... the addition of the "Natural Language ... Sciences Industry by Type (Rule-Based, Statistical, & ... Asia-Pacific, Middle East and Africa, Latin America) ... to their offering. --> http://www.researchandmarkets.com/research/pvzb7x/natural_language ...
(Date:10/8/2015)... WASHINGTON , Oct. 8, 2015  CareDx, Inc. (NASDAQ: ... a reversal of a recent proposal by the Centers for ... its FDA-cleared diagnostic test AlloMap, which measures gene expression levels ... organ rejection. See latest coverage of this story ... See latest coverage of this story on CNBC ...
Breaking Medicine Technology:
Cached News: