HOME >> MEDICINE >> NEWS
Cholesterol Carriers Better Predictors Than Cholesterol For Second Heart Attack

DALLAS, May 18 -- Two proteins that carry cholesterol in the blood may provide a better way to measure heart attack risk than the usual cholesterol blood test, report researchers in today's Circulation: Journal of the American Heart Association.

"Because the two proteins are more sensitive heart disease risk detectors than cholesterol, they may identify more individuals at risk and one day replace cholesterol testing," says the study's lead author, Arthur J. Moss, M.D., professor of medicine (cardiology) at the University of Rochester Medical Center, Rochester, N.Y.

The association between the proteins -- apolipoprotein (apo) A-1 and apolipoprotein (apo) B -- and heart attack risk held true even in the presence of heart disease risk factors including, smoking, diabetes, high blood pressure and high blood levels of cholesterol.

(Apo) A-1 and apo B carry cholesterol in the bloodstream. Apo B is a cholesterol donor, while apo A-1 is a cholesterol scavenger.

Researchers also identified a third protein, D-dimer, which was associated with heart attack risk. D-dimer is a breakdown product in the blood when clots form. Elevated levels of D-dimer indicate excess clotting or coagulation activity in the blood.

Individuals with the blood protein profile of low apo A-1, high apo B, and high D-dimer levels were eight times more likely than others in the study to experience a second heart attack within two years, Moss says. Patients with an abnormal blood level of only one of these proteins were twice as likely to experience another heart attack within two years.

When apo B levels are high, apo B deposits cholesterol on the inside surface of the plaque. Then it moves into the plaque, thereby increasing the size of the fatty deposit. Ordinarily, apo A-1 would pick up these cholesterol deposits before they enter the plaque. However, if apo A-1 levels are low, the process does not go as expected. Instead, the cholesterol accumulates and for
'"/>

Contact: Carole Bullock
caroleb@heart.org
214-706-1279
American Heart Association
18-May-1999


Page: 1 2 3

Related medicine news :

1. Cholesterol under-treated in high-risk women in managed care study
2. Cholesterol-lowering drug may also reduce risk of blood clots
3. Cholesterol-lowering drug may slow Alzheimers progression
4. Cholesterol-lowering medications may reduce risk of glaucoma
5. Cholesterol levels fluctuate with the seasons
6. Cholesterol-lowering drugs may help stroke patients get well
7. Cholesterol drugs may lower risk for mental impairment after stroke
8. Cholesterol drug increases pain-free walking distance
9. Cholesterol drug helps heart failure patients without high cholesterol
10. Cholesterol drug could lead to new therapy for multiple sclerosis
11. Cholesterol fighting drugs may also have protective effects against multiple sclerosis

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/2/2016)... NY (PRWEB) , ... December 02, 2016 , ... U.S. ... exclusive interview with Mediaplanet, Dr. Murthy explains how he was inspired to practice medicine ... I learned that medicine is about more than making diagnoses and prescribing medicine,” he ...
(Date:12/2/2016)... , ... December 02, 2016 , ... ... Beverly Hills, California, will be included in the 2016 “Guide to America’s Top ... professionals based on the amalgamation of their education, experience, and professional associations. ...
(Date:12/2/2016)... ... December 02, 2016 , ... CloudLIMS.com, a class-leading provider of ... Lite. CloudLIMS Lite helps biobanks, clinical, research and testing laboratories keep track of ... new version is a faster and a more efficient product, allowing batch processing ...
(Date:12/2/2016)... ... December 02, 2016 , ... Sourced from the Isbre Springs ... properties including its unmatched natural purity of just 6 ppm TDS (Total Dissolved Solids) ... Nothing Water has been available in several ShopRite and FoodTown stores in NJ and ...
(Date:12/2/2016)... ... 2016 , ... "Pro3rd Accents Volume 2 is a set of 30 accented ... with just a few clicks of the mouse," said Christina Austin - CEO of ... Choose from various styles with accented animations, rigid boxes, simplistic lines, and more. In ...
Breaking Medicine News(10 mins):
(Date:12/2/2016)... 2, 2016 bioLytical Laboratories (das "Unternehmen"), ein Weltführer ... seinen  INSTI HIV-Selbsttests  in einer Version mit geringeren Kosten einzuführen.  ... ... New: INSTI Self Test! (PRNewsFoto/bioLytical Laboratories) ...      (Photo: http://photos.prnewswire.com/prnh/20161201/444833 ) ...
(Date:12/2/2016)... , December 2, 2016 ... its past losses following Trump,s victory early in November. ... and fund managers are now predicting an uptick in ... four equities to see how they have fared at ... CLDX ), Amicus Therapeutics Inc. (NASDAQ: FOLD ...
(Date:11/30/2016)... Nov 30, 2016 Research and ... Overview for Neuromodulation, Neurovascular, Neurosurgical and Monitoring Devices 2017 - ... ... The full report suite on the U.S. market ... drainage systems, intracranial pressure monitoring devices, detachable coils, liquid embolics, ...
Breaking Medicine Technology:
Cached News: