HOME >> MEDICINE >> NEWS
Cholesterol Carriers Better Predictors Than Cholesterol For Second Heart Attack

DALLAS, May 18 -- Two proteins that carry cholesterol in the blood may provide a better way to measure heart attack risk than the usual cholesterol blood test, report researchers in today's Circulation: Journal of the American Heart Association.

"Because the two proteins are more sensitive heart disease risk detectors than cholesterol, they may identify more individuals at risk and one day replace cholesterol testing," says the study's lead author, Arthur J. Moss, M.D., professor of medicine (cardiology) at the University of Rochester Medical Center, Rochester, N.Y.

The association between the proteins -- apolipoprotein (apo) A-1 and apolipoprotein (apo) B -- and heart attack risk held true even in the presence of heart disease risk factors including, smoking, diabetes, high blood pressure and high blood levels of cholesterol.

(Apo) A-1 and apo B carry cholesterol in the bloodstream. Apo B is a cholesterol donor, while apo A-1 is a cholesterol scavenger.

Researchers also identified a third protein, D-dimer, which was associated with heart attack risk. D-dimer is a breakdown product in the blood when clots form. Elevated levels of D-dimer indicate excess clotting or coagulation activity in the blood.

Individuals with the blood protein profile of low apo A-1, high apo B, and high D-dimer levels were eight times more likely than others in the study to experience a second heart attack within two years, Moss says. Patients with an abnormal blood level of only one of these proteins were twice as likely to experience another heart attack within two years.

When apo B levels are high, apo B deposits cholesterol on the inside surface of the plaque. Then it moves into the plaque, thereby increasing the size of the fatty deposit. Ordinarily, apo A-1 would pick up these cholesterol deposits before they enter the plaque. However, if apo A-1 levels are low, the process does not go as expected. Instead, the cholesterol accumulates and for
'"/>

Contact: Carole Bullock
caroleb@heart.org
214-706-1279
American Heart Association
18-May-1999


Page: 1 2 3

Related medicine news :

1. Cholesterol under-treated in high-risk women in managed care study
2. Cholesterol-lowering drug may also reduce risk of blood clots
3. Cholesterol-lowering drug may slow Alzheimers progression
4. Cholesterol-lowering medications may reduce risk of glaucoma
5. Cholesterol levels fluctuate with the seasons
6. Cholesterol-lowering drugs may help stroke patients get well
7. Cholesterol drugs may lower risk for mental impairment after stroke
8. Cholesterol drug increases pain-free walking distance
9. Cholesterol drug helps heart failure patients without high cholesterol
10. Cholesterol drug could lead to new therapy for multiple sclerosis
11. Cholesterol fighting drugs may also have protective effects against multiple sclerosis

Post Your Comments:
(Date:4/18/2015)... 2015 "I recognized the need for ... facilities," said an inventor from Cincinnati, Ohio. "This need ... He developed the Slyde Door to offer an alternative ... facilities. It provides convenient storage space for an evacuation ... available for patients. , This offers added peace ...
(Date:4/18/2015)... 2015 Insuranceautoquote.info has released a new ... insurance quotes . , Clients can review important ... The online environment provides important advantages for clients who ... Drivers who do not have coverage for their vehicles ... season, day or hour. Many agencies offer important discounts ...
(Date:4/18/2015)... 2015 Patients who undergo radiation for ... later in life, but the disease is likely to ... unrelated to radiation. Surviving Mesothelioma has just posted the ... Click here to read it now. , Scientists ... of 45 patients who had both a hematologic cancer ...
(Date:4/18/2015)... More than 2000 styles of newly ... the #1 online store carrying celebrity inspired special occasion ... got their perfect dresses for their prom. For those ... dresses at TheCelebrityDresses.com would be an ideal choice. ... prom dresses inspired by the most loved styles seen ...
(Date:4/18/2015)... “ ArcAngel ” was featured on NewsWatch ... at the latest and coolest applications on the ... of AppWatch and technology expert, conducted the app review and ... , In a turbulent world, people may find themselves ... always be their first move, but some situations can be ...
Breaking Medicine News(10 mins):Health News:Clients Can Review Car Insurance Quotes Online To Find Low Cost Offers! 2Health News:New Study Examines Relationship Between Radiation for Hematologic Cancers and Development of Mesothelioma, According to Surviving Mesothelioma 2Health News:Prom Dresses 2015 on Sale at TheCelebrityDresses.com 2Health News:A Personal Safety Application was Featured on NewsWatch Television 2
(Date:4/17/2015)... 2015 Research and Markets ( http://www.researchandmarkets.com/research/5hkm2f/medical_oxygen ... Oxygen Systems - Global Strategic Business Report" report ... worldwide markets for Medical Oxygen Systems in US$ Thousands ... Oxygen Cylinders & Regulators, and Oxygen Conserving Devices. The ... Canada , Japan , ...
(Date:4/17/2015)... 2015 Today, the Pharmaceutical Research and ... 12 biopharmaceutical companies as "We Work For Health ... and community service. Established in 2009, ... created by the biopharmaceutical industry to honor employees ... but have also shown an outstanding commitment to ...
(Date:4/17/2015)... , Apr. 16, 2015 Research and ... the addition of the "The Corporate Reputation ... - Global Edition " report to their ... a Patient Perspective, is now in its fourth ... results; published early 2015). For each annual Corporate ...
Breaking Medicine Technology:Medical Oxygen Systems - 2015 Global Strategic Business Report Featuring Leading Players, Caire, Invacare & Philips Respironics 2PhRMA Applauds 2015 We Work For Health Champion Award Winners 2PhRMA Applauds 2015 We Work For Health Champion Award Winners 3The Corporate Reputation of Pharma - The Global Patient Perspective in 2014 2
Cached News: