HOME >> MEDICINE >> NEWS
Cholesterol bad for brain too, UCSF study says

Higher cholesterol levels are not only bad for the heart and blood vessels, they increase the risk of cognitive impairment, the precursor to Alzheimers disease, according to a study of elderly women by UCSF researchers.

Also, women who used cholesterol-lowering drugs called statins scored higher on tests of basic cognitive skills, such as memory, attention, and language, according to lead author Kristine Yaffe, MD, UCSF assistant professor of psychology, neurology and epidemiology, and chief of geriatric psychiatry at San Francisco Veterans Affairs Medical Center.

The higher cholesterol these women had, the worse they did on cognitive testing. And using statins, which reduce cholesterol, seemed to be beneficial to their performance on these tests, Yaffe said. Declining scores on cognitive tests are a symptom of early stage Alzheimers disease, she said.

These results fit with other studies showing that statins may help to prevent Alzheimers disease, Yaffe added. Although statins have not been proven to help the brain in a clinical trial, she explained, studies that have looked back at patients who took statins suggest they can reduce risk of Alzheimers. The current study is published in the latest issue of Archives of Neurology.

To look at cholesterols effects on the brain, Yaffe and her colleagues analyzed data retrospectively on 1037 women who had participated in the HERS clinical trial of hormone replacement therapy, because the trial had collected data on both cholesterol levels over time and tests of cognitive function. The women completed tasks that measured their abilities in memory, attention, language, orientation, and visual-spatial skills.

Women with the highest LDL-cholesterol levels, and those with the highest total cholesterol levels, had significantly poorer test scores, even after statistically correcting for differences such as age, education, and their use of hormone replacement therapy. Also, wo
'"/>

Contact: Kevin Boyd
kboyd@pubaff.ucsf.edu
415-476-8429
University of California - San Francisco
14-Mar-2002


Page: 1 2

Related medicine news :

1. Cholesterol under-treated in high-risk women in managed care study
2. Cholesterol-lowering drug may also reduce risk of blood clots
3. Cholesterol-lowering drug may slow Alzheimers progression
4. Cholesterol-lowering medications may reduce risk of glaucoma
5. Cholesterol levels fluctuate with the seasons
6. Cholesterol-lowering drugs may help stroke patients get well
7. Cholesterol drugs may lower risk for mental impairment after stroke
8. Cholesterol drug increases pain-free walking distance
9. Cholesterol drug helps heart failure patients without high cholesterol
10. Cholesterol drug could lead to new therapy for multiple sclerosis
11. Cholesterol fighting drugs may also have protective effects against multiple sclerosis

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/1/2020)... ... 2020 , ... Dr. Kiran Gill is a Board Certified ... face, breast, and body. In 2018, she founded Aesthetics in Plastic Surgery by ... practice in Southwest Florida. Dr. Gill and her team offer surgical and non-surgical ...
(Date:8/31/2020)... (PRWEB) , ... August 31, 2020 , ... Want to ... 1, Cerebral Palsy Alliance Research Foundation (CPARF) is thrilled to launch its fourth annual ... research. A fully virtual challenge, STEPtember meets everyone wherever they are at this moment ...
(Date:8/31/2020)... ... ... Covid-19 “PTS” with Mediation & Hypnosis , At this very turbulent time in the ... anxiety, immense stress, and right now are needing serious relief from a constant state of ... are experiencing a great degree of emotional discomfort, be it fear or worrying about their ...
(Date:8/28/2020)... , ... August 28, 2020 , ... ... & CEO Craig Mandeville was named an Entrepreneur Of The Year® 2020 Florida ... honors entrepreneurial business leaders whose ambitions deliver innovation, growth and prosperity as they ...
(Date:8/28/2020)... CHICAGO (PRWEB) , ... August 28, 2020 , ... ... its role in advising Adventist Health on its investment in Synchronous Health, a ... health company that combines the strength of human empathy with artificial intelligence (AI) ...
Breaking Medicine News(10 mins):
(Date:9/1/2020)... ... 01, 2020 , ... Neil Oberfeld of global law firm ... Board of Trustees and committee chair of the Governance Committee for Mile High ... organization that fights for the education, health, and financial stability of residents across ...
(Date:9/1/2020)... DETROIT (PRWEB) , ... September 01, 2020 , ... September ... among women, accounting for more deaths than any other cancer of the female reproductive ... be diagnosed with ovarian cancer and about 14,000 women will die from this disease. ...
(Date:8/31/2020)... ... August 31, 2020 , ... Continuing on ... a broad-spectrum sanitization, disinfection and deodorization provider - is proud to announce it ... disinfecting services for businesses and residents throughout the area. , Germinator provides a ...
Breaking Medicine Technology:
Cached News: