HOME >> MEDICINE >> NEWS
Cholesterol fighting drugs may also have protective effects against multiple sclerosis

ST. PAUL, MN A group of cholesterol-lowering drugs may also effectively interfere with the progression of multiple sclerosis (MS). These drugs, known as statins, greatly reduce hardening of the arteries (atherosclerosis) and heart disease, mainly by their cholesterol and low-density lipoprotein-lowering properties. A study published in the October 8 issue of Neurology, the journal of he American Academy of Neurology, indicates that statins may also have therapeutic potential for a variety of immunity related disorders such as MS, rheumatoid arthritis, type I diabetes and graft-rejection in organ transplantation.

Researchers from Austria and Germany investigated the impact of statins on a variety of immune responses in MS, comparing the effects with those induced by interferon-beta, an established disease-modifying therapy in MS. Using blood drawn from 74 MS patients and 25 healthy donors, tests were performed in vitro with lovastatin, simvastatin, mevastatin, and interferon alone, and statins plus interferon. "Our study shows that statins modify several molecules of the immune system involved in the disease progression of MS, independent of their use with interferon," notes study author Juan Jos Archelos, MD, of Karl-Franzens University, Graz, Austria. "The potent anti-inflammatory effects of statins are remarkable, and even more effective when combined with interferon-beta."

This study indicates that these well-established therapeutic agents may be a useful stand-alone or add-on therapy to interferon-beta, with the added advantage of an oral versus injectible delivery. While study results are encouraging, study authors caution that much more research is necessary to establish the precise mechanisms by which statins induce these anti-inflammatory effects.


'"/>

Contact: Cheryl Alementi
calementi@aan.com
651-695-2737
American Academy of Neurology
7-Oct-2002


Page: 1

Related medicine news :

1. Cholesterol under-treated in high-risk women in managed care study
2. Cholesterol-lowering drug may also reduce risk of blood clots
3. Cholesterol-lowering drug may slow Alzheimers progression
4. Cholesterol-lowering medications may reduce risk of glaucoma
5. Cholesterol levels fluctuate with the seasons
6. Cholesterol-lowering drugs may help stroke patients get well
7. Cholesterol drugs may lower risk for mental impairment after stroke
8. Cholesterol drug increases pain-free walking distance
9. Cholesterol drug helps heart failure patients without high cholesterol
10. Cholesterol drug could lead to new therapy for multiple sclerosis
11. Cholesterol-lowering drugs safe and effective in children

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/20/2017)... ... September 20, 2017 , ... On Thursday, the Triangle ... Work in the Research Triangle for 2017. , Winners were chosen based on ... meet a threshold in employee participation--a percentage that varies based upon the size ...
(Date:9/20/2017)... ... 20, 2017 , ... Doctors on Liens has added the medical group Bones ... working on a personal injury lien basis. Founded by Dr. Wayne Cheng, MD and ... vast experience with orthopedic injuries to patients in the Inland Empire. , Bones and ...
(Date:9/20/2017)... ... September 20, 2017 , ... ... much-anticipated fall event , Look Awesome This Autumn with CoolSculpting®. Scheduled for ... pricing and refreshments. , Mirror Mirror Beauty Boutique is Houston’s largest ...
(Date:9/20/2017)... ... September 20, 2017 , ... Announced that Clear ... commercial support services market) has entered into an agreement on September 1, 2017 ... The PGSD is the first private Dental School to launch an online, accredited ...
(Date:9/20/2017)... ... ... Compliancy Group is proud to announce that its proprietary ... long-time client pass their Department of Health and Human Services (HHS) Office for ... the help of the Compliancy Group's Audit Response Program™, not a single client ...
Breaking Medicine News(10 mins):
(Date:9/7/2017)... , Sept. 7, 2017 NuvoAir ... Smart Spirometer, announced today a partnership with Novartis Pharma AG ... solidifies NuvoAir,s position as the leading mobile spirometry platform and ... patients. ... test ...
(Date:9/6/2017)... ANTONIO , Sept. 6, 2017  Robert G. ... a Pinnacle Professional Member in recognition of his contributions ... Szewc serves as a Nephrologist at the practice of ... emergency medicine, kidney care and hypertension solutions. He has ... 20 years of career experience, as well as expertise ...
(Date:9/6/2017)... -- NeuroRx, a clinical stage biopharma company developing the first ... been granted Fast Track status by the US Food and ... followed by NRX-101 (D-cycloserine + lurasidone). The company will shortly ... therapy targeting patients who are admitted to Emergency Departments with ... ...
Breaking Medicine Technology:
Cached News: