HOME >> MEDICINE >> NEWS
Clinical trial participants fare no better, no worse than other patients

People who participate in randomized controlled studies to test new therapies seem to fare no better or no worse than those who receive the same care outside of such studies, a new review of research has found.1

The finding was published against a backdrop of debate about drug trials for popular pain-relievers and about whether trial results can be safely applied to an entire population. "These results challenge the assertion that the results of RCTs (randomized controlled trials) are not applicable to usual clinical practice," report the authors, who say this review is the most comprehensive of its kind conducted to date.

A randomized clinical trial is considered the "gold standard" of medical research because it is the best way to make sure that the only difference between the groups that are compared is the treatment they receive. Patients are assigned to each group randomly in order to increase the probability that differences between the groups can be attributed only to the treatment under study.

Critics, however, say the rigorous standards for inclusion in trials and the nature of those who conduct and participate in them mean that when a new drug or treatment is applied to a general population, the results might be different.

A recent article in the prestigious journal The Lancet suggested that clinical trials cannot be expected to be relevant to all patients with the same conditions for a number of reasons, such as selecting trial participants who are in better overall health, excluding people who have conditions in addition to the one being studied and the reality that in a general population patients will not always act according to doctors' instructions.

In the new study, researchers led by Gunn Elisabeth Vist of the Norwegian Health Services Research Centre, systematically identified and reviewed 55 studies involving a total of more than 31,000 patients who were treated in randomized clinical trials an
'"/>

Contact: GE Vist
gev@nhscr.no
Center for the Advancement of Health
23-Jan-2005


Page: 1 2 3

Related medicine news :

1. Clinical breast examination offers modest benefit to breast cancer screening program
2. Clinical trial of Etanercept for Wegeners disease shows no benefit
3. Clinical trial shows drug may offer a new option to prevent rejection of transplanted kidneys
4. National Academies news: Clinical research involving children
5. Clinical research key in advance to prospective health care
6. Clinical trial of new TB vaccine begins
7. Clinical trial of Alzheimers disease drug shows clear reductions in AD development
8. Clinical factors useful to identify heart failure patients with high risk of death
9. Panel: Clinical use of embryonic stem cells jeopardized by Bushs policy on federal funding
10. $7 million grant continues Asthma Clinical Research Network efforts
11. Clinical study of Penn State Hershey technology begins in South Africa

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Clinical trial participants fare better worse than other patients

(Date:5/22/2015)... May 22, 2015 Hands On HealthCare ... 17, 2015, the Annual One Day Sale on ... Hands On HCMT offers drastically reduced certificates one day a ... have enough sessions, through what used to be the slowest ... for the community as well. This once a year occurrence ...
(Date:5/22/2015)... Massachusetts (PRWEB) May 22, 2015 ... is a difficult process. Historically providers have not ... by payers. Starting in 2015, Medicare has paved ... coordination activities. Thanks to the launch of ... providers and health systems using the platform will ...
(Date:5/22/2015)... Coco Libre, the Official Coconut Water of Zappos.com Bay ... 104th running of the race. On Sunday, May 17, 2015, ... in one hour—one person about every 10 seconds. , ... the heart of the Bay Area, so unique, whimsical and ... finish line only made sense,” said Jennifer Goodrum, Coco Libre ...
(Date:5/22/2015)... (PRWEB) May 22, 2015 Gateway Building ... exterior renovations. The services the company specialize in include ... remodeling, basements, pool houses and much more. , ... by the owner of the company. It includes two ... The design was thought out to be used with ...
(Date:5/22/2015)... Boca Raton, FL (PRWEB) May 22, 2015 ... organization which provides vascular, electrocardiogram (EKG), echocardiogram and ... of David Sempier, a highly respected All American National ... a multi-sport athlete, I find the high level of ... to both the athlete and their athletic trainers, this ...
Breaking Medicine News(10 mins):Health News:Hands On HealthCare Massage Therapy & Wellness Day Spa Announces Their Eighth Annual One Day Sale on Gift Certificates Will Take Place on June 17, 2015 2Health News:Hands On HealthCare Massage Therapy & Wellness Day Spa Announces Their Eighth Annual One Day Sale on Gift Certificates Will Take Place on June 17, 2015 3Health News:Oculus Health Care Coordination Platform Officially Launched 2Health News:Oculus Health Care Coordination Platform Officially Launched 3Health News:Oculus Health Care Coordination Platform Officially Launched 4Health News:Coco Libre Ice Luge Sets New World Record at Bay to Breakers 2Health News:Wimbledon Athletics Recruits Team USA Athlete 2Health News:Wimbledon Athletics Recruits Team USA Athlete 3
(Date:5/22/2015)... and KING OF PRUSSIA, Pa. ... (NHF) has awarded CSL Behring its 2015 ... unwavering commitment to advancing science and improving the care of ... Paul Perreault , CEO and Managing Director, CSL Limited, during ... City on May 21. "The National ...
(Date:5/22/2015)... May 22, 2015  The Mesothelioma Victims Center ... of mesothelioma get the best possible compensation, and they ... with this rare cancer caused by exposure to ... information related to treatment options such as a ... the Mesothelioma Victims Center anytime at 866-714-6466. ...
(Date:5/22/2015)... DUBLIN , May 20, 2015 ... addition of the "Guide to Prepare Application ... in China (2014 Edition) " report to ... market is one of segment market of the ... more overseas medical device manufacturers and producers to ...
Breaking Medicine Technology:National Hemophilia Foundation Honors CSL Behring with Corporate Leadership Award 2National Hemophilia Foundation Honors CSL Behring with Corporate Leadership Award 3National Hemophilia Foundation Honors CSL Behring with Corporate Leadership Award 4Mesothelioma Victims Center Calls Attention to a Recent Medical Article About a New Drug That Could Slow the Progression of Mesothelioma and Allow People to Live Longer 2Mesothelioma Victims Center Calls Attention to a Recent Medical Article About a New Drug That Could Slow the Progression of Mesothelioma and Allow People to Live Longer 3Mesothelioma Victims Center Calls Attention to a Recent Medical Article About a New Drug That Could Slow the Progression of Mesothelioma and Allow People to Live Longer 4Mesothelioma Victims Center Calls Attention to a Recent Medical Article About a New Drug That Could Slow the Progression of Mesothelioma and Allow People to Live Longer 5China Guide to Prepare Application Dossiers for Oversea Medical Device Registration and Recordation 2China Guide to Prepare Application Dossiers for Oversea Medical Device Registration and Recordation 3
Cached News: