HOME >> MEDICINE >> NEWS
Clinical trial participants fare no better, no worse than other patients

People who participate in randomized controlled studies to test new therapies seem to fare no better or no worse than those who receive the same care outside of such studies, a new review of research has found.1

The finding was published against a backdrop of debate about drug trials for popular pain-relievers and about whether trial results can be safely applied to an entire population. "These results challenge the assertion that the results of RCTs (randomized controlled trials) are not applicable to usual clinical practice," report the authors, who say this review is the most comprehensive of its kind conducted to date.

A randomized clinical trial is considered the "gold standard" of medical research because it is the best way to make sure that the only difference between the groups that are compared is the treatment they receive. Patients are assigned to each group randomly in order to increase the probability that differences between the groups can be attributed only to the treatment under study.

Critics, however, say the rigorous standards for inclusion in trials and the nature of those who conduct and participate in them mean that when a new drug or treatment is applied to a general population, the results might be different.

A recent article in the prestigious journal The Lancet suggested that clinical trials cannot be expected to be relevant to all patients with the same conditions for a number of reasons, such as selecting trial participants who are in better overall health, excluding people who have conditions in addition to the one being studied and the reality that in a general population patients will not always act according to doctors' instructions.

In the new study, researchers led by Gunn Elisabeth Vist of the Norwegian Health Services Research Centre, systematically identified and reviewed 55 studies involving a total of more than 31,000 patients who were treated in randomized clinical trials an
'"/>

Contact: GE Vist
gev@nhscr.no
Center for the Advancement of Health
23-Jan-2005


Page: 1 2 3

Related medicine news :

1. Clinical breast examination offers modest benefit to breast cancer screening program
2. Clinical trial of Etanercept for Wegeners disease shows no benefit
3. Clinical trial shows drug may offer a new option to prevent rejection of transplanted kidneys
4. National Academies news: Clinical research involving children
5. Clinical research key in advance to prospective health care
6. Clinical trial of new TB vaccine begins
7. Clinical trial of Alzheimers disease drug shows clear reductions in AD development
8. Clinical factors useful to identify heart failure patients with high risk of death
9. Panel: Clinical use of embryonic stem cells jeopardized by Bushs policy on federal funding
10. $7 million grant continues Asthma Clinical Research Network efforts
11. Clinical study of Penn State Hershey technology begins in South Africa

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/23/2017)... Nashville, Tennessee (PRWEB) , ... August 23, 2017 ... ... expand its team to support long-term strategic growth plans, announcing the hiring of ... , A certified technology consultant and seasoned sales manager, Keelan will be working ...
(Date:8/23/2017)... ... August 23, 2017 , ... A new literature ... Surgeons , points out that therapeutic modalities (physical therapy) is an important part ... the report, a wider scope of physical therapy options is showing promising results ...
(Date:8/22/2017)... FRANCISCO BAY AREA, CA (PRWEB) , ... August ... ... premier, Nuvesse, an accessible luxurious collection of unique masks and serums that perfectly ... in scientific skin care advancements, at the 2017 Indie Beauty Expo on August ...
(Date:8/22/2017)... ... August 22, 2017 , ... The old ... is as simple as eating healthy foods. But this well-known piece of nutrition ... insulin, or breaking apart carbohydrates—depends not only on properties of the food but ...
(Date:8/22/2017)... ... August 22, 2017 , ... Pivot Point ... of Zack Tisch as the firm’s new Consulting Services Executive. Mr. Tisch will ... national accounts, from assisting clients with initial vendor selection and pre-implementation planning through ...
Breaking Medicine News(10 mins):
(Date:7/31/2017)... 2017  Diplomat Pharmacy, Inc. (NYSE: DPLO), has been named ... by Crain,s Detroit Business . ... by three-year revenue growth. This year,s edition measures growth from ... view the complete list, visit crainsdetroit.com/awards/fast_50/2017 .  ... triumph," said Phil Hagerman , CEO and chairman of ...
(Date:7/28/2017)... EnvoyHealth, a Diplomat company, has partnered with Compliance ... LITE, a technology designed to improve patient medication adherence. ... technology solutions and services that help track and improve ... CleverCap LITE offers medication monitoring and control for patients ... Records date and time of ...
(Date:7/26/2017)... a leading medical aesthetic clinic in Singapore ... conditions from the inside. The natural process of aging ... becomes more transparent due to the thinning of the epidermis. Over the ... sun contributes to aging skin, causing age spots and other types ... ...
Breaking Medicine Technology:
Cached News: