Clot-Busters As Effective As Surgery To Clear Blockages In Legs

putation, whether patients received conventional surgical treatments or the drug. Moreover, the length of hospital stay was similar in the two groups. The team did notice an increased risk of bleeding in the urokinase group.

The clot-buster the team studied is an experimental compound known as recombinant urokinase. Standard urokinase, marketed as Abbokinase by Abbott, is approved to clear blood clots in the heart and lungs and is often used by physicians to treat blood clots in the legs. The overall cost of surgery and the cost of the medication are about the same, says Ouriel, noting that a typical supply of the drug for one patient costs the hospital about $3,500.

"For many surgeons today, the standard of care for these patients is to take them urgently to the operating room," says Ouriel. "Our results show that patients receiving urokinase can experience success rates equivalent to that of surgery, but the frequency and extent of open surgical procedures is reduced."

More than 30 percent of patients avoided open surgical procedures by using the drug, the physicians found. Of those taking the drug who then went on to have surgery, the operation was often less invasive than would have been required without the drug -- for instance, patching a narrow segment of an artery rather than placing a completely new bypass graft.

Even with all of these options -- drugs, surgery, or a combination -- about one-quarter of patients died or lost their leg within six months.

Ouriel says that in major medical centers, thrombolysis is often the first treatment patients receive, but word is just beginning to spread to all vascular surgeons.

"Instead of taking these patients to the operating room immediately, we can infuse a thrombolytic agent over a day or so," says Ouriel. "If we do need to operate, it's frequently a much smaller operation, such as patching one small area. Thrombolysis lets surgeons be selective in whom they operate o

Contact: Tom Rickey
University of Rochester

Page: 1 2 3

Related medicine news :

1. HIV-1 protease inhibitors: Effective against malaria?
2. Effectiveness of safer smallpox vaccine demonstrated against monkeypox
3. Effectiveness of chickenpox vaccine decreases after one year
4. Effective treatment for diabetes depends on the underlying cause
5. Effectiveness of drugs used to treat Parkinsons disease in early, later stages measured
6. Effective treatment for children with ADHD and chronic tic disorders
7. Effective Clinical Practice, Jan/Feb. 2002 Highlights
8. Effective surgery fails to attract patients unless costs are low
9. Effective Clinical Practice, Nov/Dec 2000 highlights
10. Effective Clinical Practice, Sept/Oct 2000 highlights
11. Randomized Contolled Study Shows Neostigmine Is An Effective Treatment For Acute Colonic Pseudo-Obstruction

Post Your Comments:

(Date:9/17/2019)... ... September 17, 2019 , ... Dr. Perry Patel, the ... by the American Academy of Facial Esthetics (AAFE) to administer Botox and dermal ... orofacial conditions such as tooth clenching and grinding, tongue tension, temporomandibular joint disorders, ...
(Date:9/17/2019)... ... September 17, 2019 , ... ... of services, welcomes Dr. Yevgeniya (Jenny) Gartshteyn to their team of expert physicians. ... she previously held the Clinical Appointment of Assistant Professor in Medicine for the ...
(Date:9/12/2019)... COLUMBUS, Ohio (PRWEB) , ... September 12, 2019 ... ... recognized on both a local and national scale in two recent and well-renowned ... the country’s fastest-growing privately held businesses for the 2019 year. , Dr. ...
(Date:9/11/2019)... ... September 11, 2019 , ... ... accredited continuing medical education (CME) provider, is the official accreditor for PAINWeek, the ... vetted speakers, and screened topics, as it has done for the past ten ...
(Date:9/11/2019)... ... 11, 2019 , ... Autopsies don’t lie. They report the causes of ... Methamphetamine permanently harms the heart. It increases risks of heart attack and death. ... how the damage occurs. , An August 1, 2019 article in ...
Breaking Medicine News(10 mins):
(Date:9/17/2019)... ... September 17, 2019 , ... Dr. Arta Farahmand welcomes ... . An alternative to conventional orthodontics, the Wilckodontics orthodontic system often cuts treatment ... Conventional orthodontics uses brackets and wires that apply constant pressure on the teeth, ...
(Date:9/17/2019)... ... September 17, 2019 , ... The Society to Improve Diagnosis in ... Moore Foundation to launch the DxQI Seed Grant Program. The new program will engage ... quality and reducing harm from diagnostic error. , SIDM will open the application ...
(Date:9/17/2019)... N.Y. (PRWEB) , ... September 17, 2019 , ... Gustavo ... 31 credit CME conference on Yoga Science as holistic mind/body medicine for physicians and ... comprehensive training being held October 22-26, 2019 at the Cranwell Resort and Spa in ...
Breaking Medicine Technology:
Cached News: