Clot-Busters As Effective As Surgery To Clear Blockages In Legs

putation, whether patients received conventional surgical treatments or the drug. Moreover, the length of hospital stay was similar in the two groups. The team did notice an increased risk of bleeding in the urokinase group.

The clot-buster the team studied is an experimental compound known as recombinant urokinase. Standard urokinase, marketed as Abbokinase by Abbott, is approved to clear blood clots in the heart and lungs and is often used by physicians to treat blood clots in the legs. The overall cost of surgery and the cost of the medication are about the same, says Ouriel, noting that a typical supply of the drug for one patient costs the hospital about $3,500.

"For many surgeons today, the standard of care for these patients is to take them urgently to the operating room," says Ouriel. "Our results show that patients receiving urokinase can experience success rates equivalent to that of surgery, but the frequency and extent of open surgical procedures is reduced."

More than 30 percent of patients avoided open surgical procedures by using the drug, the physicians found. Of those taking the drug who then went on to have surgery, the operation was often less invasive than would have been required without the drug -- for instance, patching a narrow segment of an artery rather than placing a completely new bypass graft.

Even with all of these options -- drugs, surgery, or a combination -- about one-quarter of patients died or lost their leg within six months.

Ouriel says that in major medical centers, thrombolysis is often the first treatment patients receive, but word is just beginning to spread to all vascular surgeons.

"Instead of taking these patients to the operating room immediately, we can infuse a thrombolytic agent over a day or so," says Ouriel. "If we do need to operate, it's frequently a much smaller operation, such as patching one small area. Thrombolysis lets surgeons be selective in whom they operate o

Contact: Tom Rickey
University of Rochester

Page: 1 2 3

Related medicine news :

1. HIV-1 protease inhibitors: Effective against malaria?
2. Effectiveness of safer smallpox vaccine demonstrated against monkeypox
3. Effectiveness of chickenpox vaccine decreases after one year
4. Effective treatment for diabetes depends on the underlying cause
5. Effectiveness of drugs used to treat Parkinsons disease in early, later stages measured
6. Effective treatment for children with ADHD and chronic tic disorders
7. Effective Clinical Practice, Jan/Feb. 2002 Highlights
8. Effective surgery fails to attract patients unless costs are low
9. Effective Clinical Practice, Nov/Dec 2000 highlights
10. Effective Clinical Practice, Sept/Oct 2000 highlights
11. Randomized Contolled Study Shows Neostigmine Is An Effective Treatment For Acute Colonic Pseudo-Obstruction

Post Your Comments:

(Date:6/18/2019)... ... , ... HR Maximizer Inc ( https://hrmaximizer.com ) announced today ... Healthcare HR Association (HHHRA - https://hhhra.org ). In addition to having ... PageUp, CRC, Alliance Work Partners and Kognito. , Houston Healthcare HR Association, The ...
(Date:6/16/2019)... , ... June 15, 2019 , ... Convoy of Hope ... has been committed to helping those in need around the world. To date, Convoy ... than 125 countries. Convoy’s work would not be possible without the dedication and generosity ...
(Date:6/13/2019)... DETROIT (PRWEB) , ... June 13, 2019 , ... Endometriosis is a painful, inflammatory disease ... , Painful periods , Heavy bleeding , ... Constipation , Women’s Excellence uses the latest and newest treatment protocols in ...
(Date:6/13/2019)... ... June 13, 2019 , ... Pure Ratios, the ... cannabis delivery company, Driven Deliveries, Inc., the only publicly traded cannabis delivery service ... the population of California with overnight cannabis delivery to major thriving markets such ...
(Date:6/13/2019)... (PRWEB) , ... June 13, 2019 , ... Clinical ... experience, is pleased to announce that Jonathan Andrus , chief business officer at ... by the Duke-Margolis Center for Health Policy on July 1, 2019, in ...
Breaking Medicine News(10 mins):
(Date:6/14/2019)... (PRWEB) , ... June 14, 2019 , ... ... National Cyclotron and PET Centre, Chulabhorn Hospital announced today a research collaboration to ... of aging Thai individuals. The first subjects have been recruited and imaged. LMI ...
(Date:6/13/2019)... (PRWEB) , ... June 13, 2019 , ... ... as a Prime awardee of the Network of Quality Improvement and Innovation Contractor. ... five years. As a Prime NQIIC awardee partnering with other Quality Improvement ...
(Date:6/13/2019)... ... June 13, 2019 , ... ... has announced the new Smart Scheduling product, part of the HCHB Intelligence Suite, ... Scheduling product uses complex algorithms to create highly efficient routing, mapping and scheduling ...
Breaking Medicine Technology:
Cached News: