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Clot-Busters As Effective As Surgery To Clear Blockages In Legs

n, and converts an emergency procedure to an elective one."

Not all physicians are as enthusiastic. In an accompanying editorial in the journal, John Porter of the Oregon Health Sciences University School of Medicine concludes from the same data that drug therapy does not improve clinical outcome. Citing the increased risk of bleeding, he concludes, "For the time being, I do not regard thrombolytic therapy as first-line treatment for acute arterial thromboembolism of the legs."

Like Ouriel, co-author Veith disagrees, saying the study does support the idea that drugs should be a part of the treatment regimen. "These drugs have a useful place in the treatment of acute arterial blockages in the legs. Urokinase spares fairly aggressive and invasive treatment in a number of cases."


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Contact: Tom Rickey
trickey@admin.rochester.edu
716-275-7954
University of Rochester
15-Apr-1998


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