HOME >> MEDICINE >> NEWS
Coffee drinking elevates plasma homocysteine and risk factors for coronary heart disease

High plasma homocysteine concentration is associated with an increased risk of cardiovascular disease, and consumption of unfiltered and filtered coffee raises homocysteine levels. As yet, it is unclear which substances in brewed coffee are responsible for its homocysteine-raising properties. In an article published in this month's American Journal of Clinical Nutrition, Verhoef et al. investigated the effects of caffeine alone and in brewed coffee on homocysteine concentrations in a group of healthy volunteers. Brewed coffee increased homocysteine levels within hours of consumption and seemed to have a particularly strong effect when taken after meals.

The 21 male and 27 female participants in the study, aged 19 to 65 years old, were all heavy coffee drinkers who consumed 6 or more cups of filtered or instant coffee daily. Thirty-one percent of the subjects were smokers, who are known to metabolize caffeine more rapidly than non-smokers. Three treatments, administered in random order for a period of 2 weeks each, consisted of either capsules containing 870mg of caffeine daily; 4 cups of strong filtered coffee that contained 870 mg of caffeine; or placebo capsules. Despite the fact that both treatments had a similar amount of caffeine, the average fasting homocysteine concentration rose by 11% after the subjects drank brewed coffee for 2 weeks, compared to a 5% increase after caffeine alone. The paper filter in the brewed coffee retained trace amounts of several substances that were suspected to be responsible for the rise in homocysteine concentrations, including chlorogenic acid (a polyphenolic compound) that is not removed by filtering.

Epidemiologic associatations between coffee consumption and CVD are conflicting; therefore, public health implications of the homocysteine-raising effects of caffeine and coffee will remain unclear until a causal relation between high homocysteine concentrations and CVD is proven.


'"/>

Contact: Elizabeth Horowitz
horowitz@ascn.faseb.org
301-530-7038
American Journal of Clinical Nutrition
21-Nov-2002


Page: 1

Related medicine news :

1. Coffee drinking associated with reduced risk of diabetes
2. Coffee addicts at reduced risk of type 2 diabetes?
3. Coffee: a cause of neonatal seizures?
4. Morning Coffee Boosts Blood Pressure, Stress Hormones All Day
5. Binge drinking can impair both mood and cognitive performance
6. Medication helps alcoholics control drinking
7. Studies examine coffee drinking and risk of liver and colorectal cancers
8. Using the internets power and anonymity to reduce problem drinking
9. State policies decrease youth smoking, drinking and sex
10. Women, drinking to their health
11. National Academies Advisory: Jan. 11 public briefing on perchlorate in drinking water

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... , ... October 13, 2017 , ... Apple Rehab ... services, staged a mock evacuation of the facility as part of a disaster drill ... Department, Echo Hose EMS and Shelton City Emergency Manager, as well as the ...
(Date:10/13/2017)... ... October 13, 2017 , ... The Visiting Nurse Association (VNA) of Somerset Hills ... specialty vendors and unique items from across the nation, this holiday-themed event will raise ... offered by the VNA. The boutique will be open Saturday, November 4 (10:00 ...
(Date:10/13/2017)... NJ (PRWEB) , ... October 13, 2017 , ... Global ... at scenic Alexandria Park in Milford, NJ. This free event, sponsored by Global ... physical activity. The fun run is geared towards children of all ages; it ...
(Date:10/13/2017)... ... October 13, 2017 , ... Talented host, actor Rob ... sciatica in a new episode of "Success Files," which is an award-winning educational ... and investigates each subject in-depth with passion and integrity. , Sciatica occurs when ...
(Date:10/13/2017)... ... October 13, 2017 , ... “The Journey: From the Mountains to ... to save lost souls in the Philippines. “The Journey: From the Mountains to the ... teacher of the Bible. She has taught all ages and currently teaches a class ...
Breaking Medicine News(10 mins):
(Date:10/11/2017)...  Caris Life Sciences ® , a leading innovator ... precision medicine, today announced that St. Jude Medical Center,s ... (POA) as its 17 th member. Through participation ... Cancer Institute will help develop standards of care and ... making cancer treatment more precise and effective. ...
(Date:10/10/2017)... --  West Pharmaceutical Services, Inc. (NYSE: WST), a ... today shared the results of a study highlighting the ... administration of polio vaccines. The study results were presented ... by Dr. Ondrej Mach , Clinical Trials and ... and recently published in the journal Vaccine. i ...
(Date:10/4/2017)... to the Centers for Disease Control and Prevention (CDC), influenza vaccination ... is helping communities across Massachusetts , Connecticut ... flu shots through the end of the month. *Some exclusions ... ... shot is by the end of October, according to the Centers for ...
Breaking Medicine Technology:
Cached News: