HOME >> MEDICINE >> NEWS
Coffee drinking elevates plasma homocysteine and risk factors for coronary heart disease

High plasma homocysteine concentration is associated with an increased risk of cardiovascular disease, and consumption of unfiltered and filtered coffee raises homocysteine levels. As yet, it is unclear which substances in brewed coffee are responsible for its homocysteine-raising properties. In an article published in this month's American Journal of Clinical Nutrition, Verhoef et al. investigated the effects of caffeine alone and in brewed coffee on homocysteine concentrations in a group of healthy volunteers. Brewed coffee increased homocysteine levels within hours of consumption and seemed to have a particularly strong effect when taken after meals.

The 21 male and 27 female participants in the study, aged 19 to 65 years old, were all heavy coffee drinkers who consumed 6 or more cups of filtered or instant coffee daily. Thirty-one percent of the subjects were smokers, who are known to metabolize caffeine more rapidly than non-smokers. Three treatments, administered in random order for a period of 2 weeks each, consisted of either capsules containing 870mg of caffeine daily; 4 cups of strong filtered coffee that contained 870 mg of caffeine; or placebo capsules. Despite the fact that both treatments had a similar amount of caffeine, the average fasting homocysteine concentration rose by 11% after the subjects drank brewed coffee for 2 weeks, compared to a 5% increase after caffeine alone. The paper filter in the brewed coffee retained trace amounts of several substances that were suspected to be responsible for the rise in homocysteine concentrations, including chlorogenic acid (a polyphenolic compound) that is not removed by filtering.

Epidemiologic associatations between coffee consumption and CVD are conflicting; therefore, public health implications of the homocysteine-raising effects of caffeine and coffee will remain unclear until a causal relation between high homocysteine concentrations and CVD is proven.


'"/>

Contact: Elizabeth Horowitz
horowitz@ascn.faseb.org
301-530-7038
American Journal of Clinical Nutrition
21-Nov-2002


Page: 1

Related medicine news :

1. Coffee drinking associated with reduced risk of diabetes
2. Coffee addicts at reduced risk of type 2 diabetes?
3. Coffee: a cause of neonatal seizures?
4. Morning Coffee Boosts Blood Pressure, Stress Hormones All Day
5. Binge drinking can impair both mood and cognitive performance
6. Medication helps alcoholics control drinking
7. Studies examine coffee drinking and risk of liver and colorectal cancers
8. Using the internets power and anonymity to reduce problem drinking
9. State policies decrease youth smoking, drinking and sex
10. Women, drinking to their health
11. National Academies Advisory: Jan. 11 public briefing on perchlorate in drinking water

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/14/2019)... ... September 14, 2019 , ... GreenTheVoteOk , one of the ... again tried to bring the most relevant and important developments in the fast-changing world ... increasingly large number of people across the world suffering from different difficult-to-treat ailments, people ...
(Date:9/11/2019)... Pa. (PRWEB) , ... September 12, 2019 , ... “Heart ... living with diagnosed coronary artery disease as he hopes to prevent anyone from having ... creation of published author John Saltwick, a writer who was diagnosed with coronary artery ...
(Date:9/11/2019)... ... 11, 2019 , ... A September 2 article on CBS News ... significantly less likely to suffer heart attacks, strokes, kidney failure, and heart disease versus ... weight loss surgery specialists Dr. Feiz and Associates says the study adds further evidence ...
(Date:9/11/2019)... (PRWEB) , ... September 11, 2019 , ... ... will be held September 11-14 in Minneapolis at the Mall of America Radisson ... LaPrade, will be faculty members for the high-profile, knee-focused conference, which brings together ...
(Date:9/11/2019)... DANBURY, Conn. (PRWEB) , ... September 11, 2019 , ... ... helps couples and individuals grow their family, will host a free informational event that ... and a food truck meal voucher for the first fifty registrants. The event, “What’s ...
Breaking Medicine News(10 mins):
(Date:9/14/2019)... BOSTON (PRWEB) , ... September 13, 2019 , ... ... provider of teledentistry services for employers, became the first commercial teledentistry practice in ... an award-winning startup with other hub entrepreneurs, company leaders, innovators and industry experts ...
(Date:9/14/2019)... ... ... The Allergenic Products Advisory Committee of the Food and Drug Administration (FDA) ... approval of a standardized oral immunotherapy (OIT) product for peanut allergy. The brand name ... The FDA would require a Risk Evaluation and Mitigation Strategy (REMS) to be developed ...
(Date:9/12/2019)... ... ... Stratosphere Networks will sponsor GRIN2B Foundation’s first cocktail reception fundraiser, Gather ... Kitchen and Social House in Evanston from 6 p.m. to 9 p.m. , Proceeds ... gene on the short arm of the 12th chromosome and is part of a ...
Breaking Medicine Technology:
Cached News: