Columbia study finds differences in PSA, PSA density test measurements for Caucasian, Hispanic men

Doctors at NewYork-Presbyterian Hospital's Columbia Presbyterian campus will report today the results of one of the few studies to look at the performance of prostate-specific antigen (PSA) tests in the detection of prostate cancer in Hispanics as compared to Caucasians. The study shows when the test is extended to the point of measuring PSA density (PSAD), it is better able to predict whether a man has malignant or benign disease if the man is a Caucasian than if he is Hispanic.

Dr. Erik Goluboff, assistant professor of urology at Columbia University College of Physicians & Surgeons and the senior author of the study - which is being presented at the meeting of the American Urological Association in Orlando, Florida - said that there is a "cutoff point"-0.15-above which readings in the PSAD have a 40% likelihood of being correlated with confirmed cases of malignant disease in Caucasian men. That cutoff point is, however, not useful with Hispanic men. "We don't know what it is, but we should probably have a different cutoff point for Hispanic men in interpreting the PSAD, or some other way of managing the Hispanic PSADs," said Dr. Goluboff, who is Director of Urology at the Allen Pavilion of NewYork-Presbyterian Hospital.

The authors, who also include Drs. John S. Lam, James M. McKiernan, Aristotelis G. Anastasiadis, and Mitchell C. Benson, note that although many studies have looked at PSA tests in Caucasians and African-Americans, few have addressed Hispanics. They set out to compare the performance of the test in groups of Hispanics and Caucasians.

A total of 404 Hispanics and 341 non-Hispanic Caucasians who had "elevated" PSA or abnormal rectal exam underwent transrectal ultrasound and biopsies between 1996 and 2001 at the Hospital. (Men were classified as Hispanic if they identified themselves that way, or by their surname.) Prior to biopsy, all patients underwent volume measurements of the entire prostate.

Of these

Contact: Annie Bayne
Columbia University Medical Center

Page: 1 2 3

Related medicine news :

1. Columbia researchers receive $3 million to combat genetic killer of infants & toddlers
2. Columbia study shows widely used artery clearing device does not help patients during heart attack
3. Columbia study finds hemophilia therapy dramatically improves outcomes for bleeding stroke
4. First US kidney cancer vaccine trial underway at Columbia
5. RelayHealth selected by Columbia University to link doctors and patients online
6. Harlem Hospital Center, Columbia affiliate, recognized for efforts to fight glaucoma
7. Research by scientists affiliated with the Earth Institute at Columbia University
8. Columbia Univ. Medical Center wins highly competitive stroke grant from NIH
9. Brain Science Institute at Columbia University established by Kavli Foundation gift
10. Earth Institute at Columbia University hosts State of the Planet 2004
11. The Gerontological Society of America confers 2003 Lawton Award to Columbia Universitys Gurland

Post Your Comments:

(Date:5/14/2020)... ... ... , a premier fertility and IVF center and home to 85,000 babies, announced today it ... , “While this pandemic has tested us, we are resilient and stronger than ever. I’m ... occasion. Through the work of many, I am happy that we are able again to ...
(Date:5/14/2020)... ... May 14, 2020 , ... T1 Payments , ... COVID-19 Emergency Response Fund in an effort to assist with the State’s response, ... Foundation and Nevada COVID-19 Response, Relief, and Recovery Task Force are partnering to ...
(Date:5/14/2020)... ... May 13, 2020 , ... Palo Alto University has ... allows students to earn their degree in less than two years. On May 20, ... students interested on Wednesday, May 20, 2020 from 4:00pm to 5:00pm. , The ...
(Date:5/14/2020)... ... May 14, 2020 , ... Slone Partners ... has announced the placement of Ingo Chakravarty as President and Chief Executive Officer ... than two months after it received Emergency Use Authorization (EUA) from the ...
(Date:5/11/2020)... CITY (PRWEB) , ... May 11, 2020 , ... ... by SpringTide Investments and Rock Creek Capital with additional ... easy-to-implement digital dermatopathology solutions that can speed the diagnostic process while reducing costs ...
Breaking Medicine News(10 mins):
(Date:5/21/2020)... ... May 21, 2020 , ... In today’s news cycle we ... to touch or shake hands with others; to avoid restaurants, movie theaters, concerts, sporting ... with your Netflix, AppleTV+, YoutubeTV or Prime Video subscriptions. But as things begin to ...
(Date:5/21/2020)... ... May 21, 2020 , ... MedTech ... and products in the global health and medical technology market, today announced that ... been selected as the winner of its “Health Administration Innovation Award” in the ...
(Date:5/21/2020)... ... May 21, 2020 , ... Today Anyblock Analytics, ... the Corona SeroStatus app. Many facilities, cities, states/provinces, and countries are eager to ... coronavirus globally—including nearly 1.5 million in the United States alone—serious concerns remain about ...
Breaking Medicine Technology:
Cached News: